Mannit. Instructions for use

The medicine "Mannit", whose price is about 90 rubles, belongs to the group of diuretic medicines. The preparation is in the form of a solution for infusions. The active substance is mannitol. The agent helps to increase the osmotic pressure in the plasma. The medicine provokes water retention and an increase in the volume of urine. The drug is not able to penetrate through tissue and cellular barriers, does not increase the residual nitrogen. The agent "Mannit" (instructions for use contains such data) is characterized by poor absorption, and therefore injected intravenously. There is a slight metabolism in the liver. The drug is excreted in the urine.

Indications

The drug "Mannitol" is prescribed for edema of the brain, intracranial pressure (against renal-hepatic or renal failure). The drug is used for posttransfusion complications in connection with the introduction of incompatible blood, diuresis (forced) against the background of poisoning with salicylates, barbiturates. The drug "Mannit" instructions for use recommends in oliguria on the basis of renal-hepatic or renal failure acute flow with a preserved filtration function of the organs (in complex therapy). The medication is prescribed for the prevention of hemolysis in operations using extracorporeal circulation to prevent ischemia in the kidney and the likely acute failure of the renal system.

Contraindications

The "Mannitol" (application instruction indicates this) is not allowed for use in anuria accompanying acute renal tubular necrosis, hypersensitivity, left ventricular failure (especially with pulmonary edema). The drug is not recommended for subarachnoid hemorrhage (with the exception of bleeding during the trepanation of the skull), hemorrhagic stroke, severe dehydration, hypokalemia. Contraindications include hypochloraemia, hyponatremia. Caution when prescribing is observed with elderly patients. The expediency of using the drug during pregnancy or during lactation is established by a specialist.

The drug "Mannit." Instructions for use

Intravenously drip or struyno drug is introduced slowly. For preventive maintenance appoint a drug in a dose of 0.5 g / kg of weight, for treatment - 1-1.5 g / kg. On the day the amount of the drug should not be more than 140-180 g. Before carrying out the infusion, the "Mannit" remedy recommends that the instruction for use be heated to a temperature of 37 degrees. During interventions using artificial circulation, the drug is used at a dose of 20-40 g. Patients with oliguria are administered a preliminary trial dose of 200 mg / kg for three to five minutes. If there is no increase in the diuresis speed within 2-3 hours to a level of 30-50 ml / h from the administration of the drug, it is necessary to refuse.

The drug "Mannit." Instructions for use. Side effect

On the basis of the use of medicines, dehydration, lowering of pressure, a disorder in water-electrolyte metabolism, muscle weakness, dyspepsia are noted.