The drug is "Safocid". Instructions for use

The drug "Safocid" - a combined agent that contains in the composition of secnidazole, fluconazole, azithromycin. The drug exhibits antifungal, antiprotozoal and antibacterial action. Fluconazole is able to selectively inhibit the synthesis of sterols in mushroom cells. Its activity is manifested in respect to microspores, cryptococci, trichophytias, candidiasis. Azithromycin belongs to the category of azalid antibiotics. This substance has a bactericidal effect, creating high concentrations in inflammation foci. Azithromycin acts on mycoplasmas, chlamydia, Neisseria, Gardnerella, streptococci, ureaplasma, treponema. The component does not affect gram-positive microflora, resistant to erythromycin. Secnidazole has antiprotozoal, antimicrobial activity. The component does not affect the aerobes. Seknidazole provokes sensitization to alcohol-containing compounds, increases the sensitivity of neoplasms to the effects of irradiation. The mechanism of the activity of the component is determined by the ability to break down the spiral structure of DNA, suppress the synthesis of nucleic acids, which facilitates the rupture of the bonds and death of bacterial cells.

The drug is "Safocid". Instructions for use. Appointment

Indications include combined lesions of the genitourinary system of the infectious type, transmitted by sexual contacts. A medication is prescribed for cystitis, urethritis, gonorrhea, chlamydia. The drug is recommended for vulvovaginitis, cervicitis, bacterial vaginosis, trichomoniasis, fungal infections of the reproductive system.

Contraindications

The drug "Safocid" (instructions for use warns about this) is not recommended for pathologies of the central nervous system of organic type, intolerance of its components, and also during pregnancy. Do not prescribe the product at the same time as taking medications such as Terfenadine, Astemizol, and others that help prolong the QT interval. Contraindications also include the period of lactation.

Side effect

To negative consequences of therapy by means of "Safocid" the instruction on application includes the disorder of taste sensitivity, disturbances of a heart rhythm, activity of system of digestion. The drug can provoke flatulence, epigastric pain, stomatitis, skin reactions, nausea. In some cases, diarrhea, vomiting, anaphylactic shock, dizziness, or headaches are noted.

Dosage regimen of the medicament "Safocid". How to take the drug

Assign means inside. There are four tablets in the blister, they are taken once. It is recommended to drink the remedy two hours after or one hour before a meal.

Additional Information

Against the background of therapy with "Safocid" (the instructions for use contain such data), while using it with the drug "Warfarin", an increase in the prothrombin index by an average of 12% can be noted. During the preparation of coumarin anticoagulants, it is necessary to control the changes in prothrombin time. It should be considered during the therapy to slow down the rate and volume of absorption when eating.