Clomifen: reviews. "Klomifen": instructions for use, description, price

"Clomiphene citrate" is a synthetic non-steroid drug, characterized in pharmacology as an anti-estrogen. It is widely used for medical purposes as a stimulator of ovulation in women, and in bodybuilding as a means for building muscle mass.

The effect of the drug "Clomifene" is based on its partial structural similarity with estrogen, which is produced in the human body. Due to this, the main substance of the described agent can bind to the hormone receptors of estrogen, which stimulates the increase in the production of gonadotropins of FSH and LH. And this, in turn, increases the secretion of testosterone in men and estrogen in women.

Further in the article, we will describe in more detail the effect of the drug Klomifen in various cases of its use.

How the drug is used in medicine

This drug is prescribed for men with androgen deficiency, with oligospermia and delay in sexual and physical development in adolescents.

The drug "Clomiphene Citrate" is also popular in gynecology as a tool that can help a woman with diagnosed ovarian dysfunction, ranging from minor deviations to serious pathologies.

For women, this drug is indicated for uterine bleeding, postcontraceptive amenorrhea, galactorrhea that has arisen against the background of the tumor, as well as in polycystic ovaries - the result will not be long in coming. The main thing at the same time is precisely to establish the causes of the pathological condition and to form an adequate therapeutic course.

Since "Klomifen" - tablets with a strong effect of exposure, their long-term use is impractical. And to prevent this, the doctor must determine the exact time to start the course. For this, for example, a woman with anovulatory infertility is offered to undergo an ovulation test (usually done from the twelfth to the fifteenth day with a 28-day cycle or from the eleventh to the twentieth - with an irregular one) that helps to specify the dates of the first and last day of treatment.

How to induction of ovulation with the drug "Clomifen": instruction

Induction of ovulation (stimulation of the process of egg maturation with the help of special medicines) is usually shown to patients with rare menstruation, to those who do not have it, and to those whose infertility can not be ascertained. All of them are usually prescribed the most effective drug for such cases, according to experts, which is Clomiphene.

Testimonials of medical practitioners confirm that it should be taken for five days at the very beginning of the cycle (the standard dose is 50 mg per day at bedtime, regardless of food intake). The course of the induction process should be monitored by a specialist, checking its results with ultrasound, baseline temperature measurements and determining the amount of estrogen in the blood.

As a rule, due to the effect of the drug, ovulation occurs 5 days after the last dose of the drug, but in some patients it can take from 18 to 23 days. In such cases, the development of follicles is monitored by ultrasound.

By the way, taking Clomifene increases the likelihood of multiple pregnancy.

Side effects that prevent pregnancy, when using the drug

Despite the relative safety of the described remedy, the experts' opinions on the Clomifene preparation emphasize its ability to provoke the inferiority of the mucus secreted in the cervix. And this, in turn, can be a barrier to sperm, as a result of which even with good ovulation the woman has problems with conception. To avoid this problem, doctors recommend that patients in the first half of the cycle perform postcoital testing after each induction of Clomiphen.

Another negative consequence of using the described agent is the possibility of reducing the quality of the endometrium. This is manifested in the fact that it is thinned, why successful implantation of the fetal egg becomes practically impossible.

In addition to the listed side effects, some experts also note complaints of patients for hot flushes, visual impairment, vaginal dryness, and also a manifestation of ovarian hyperstimulation syndrome. In some women, the growth of cysts in the ovary can also be observed, which makes it necessary to conduct an ultrasound before the course of induction.

Contraindications for use

It should be mentioned that this drug is taken orally, while it is well absorbed and metabolized by the liver. The half-life period, as a rule, is from 5 to 7 days.

The reviews on Clomifene are also warned against contraindications to its use. It can not be assigned:

• Pregnant,
• Patients with severe impairment of liver or kidney function,
• With uterine bleeding of unclear etiology,
• Ovarian cyst,
• Propensity to thrombosis,
• With tumors or hypofunction of the pituitary gland,
• And also in the presence of malignant and benign neoplasms in the genital organs.

All these diseases serve as a serious obstacle to the prescription of the drug, so they should be reported to the treating doctor in a timely manner.

The use of Clomiphen in bodybuilding

As already mentioned above, the described device is used not only for medical purposes: both novice athletes and professionals actively use the drug "Clomifen". Its use in sports is explained by excellent indicators in the buildup of muscle mass and the fact that unlike many similar drugs, it does not reduce the concentration of natural testosterone in the blood, but, on the contrary, leads to its increased production.

In addition, experts suggest that men take the drug and with the occurrence in some cases after the course of steroids of gynecomastia (an increase in men in the breast). By the way, the anti-estrogen "Klomifen" to some extent has anabolic properties, although not as powerful as in steroid preparations.

The drug "Clomifen": instructions for use in bodybuilding

In heavy sports and bodybuilding, the Clomiphen preparation is taken, as a rule, regardless of the weight or other indices of the athlete. Its dosage usually ranges from 50 to 150 mg per day at a time. According to experts, a larger amount of the drug is inappropriate, because even its minimum dose (50 mg) can significantly affect the increase in testosterone and muscle growth.

The course of reception of the described means lasts no more than three weeks. And, as evidenced by the reviews, this term is enough to make the effect of its application become obvious.

Feedback on the admission of the drug "Klomifen"

About the preparation "Clomifen" reviews are quite easy to find, as it enjoys an enviable popularity among both gynecologists and athletes-athletes.

True, among the many laudatory reviews there are also negative statements. But they are based, as practice proves, on the wrong and uncontrolled admission of the named means, which, naturally, entails negative consequences. As a rule, they include nausea, vomiting, headache, uncomfortable and painful sensations in the area of the mammary glands, as well as an increase in temperature.

Patients' complaints about mood swings and insomnia associated with taking Klomiphen tablets are also frequent.

But experts confirm once again that in most cases all these phenomena are caused by improper selection of the dosage of the drug and disappear soon after its withdrawal.

A little more about the tablets "Klomifen"

To avoid fakes of this very popular drug, it is best to buy the drug "Klomifen" in the pharmacy. It is available in the form of round white tablets, placed in a contour package of ten pieces or in a plastic jar.

One tablet contains 0.05 g of clomiphene citrate, and also auxiliary substances in the form of lactose, potato starch, food gelatin, magnesium stearate and talc.

Special remarks about the drug "Klomifen"

Judging by the opinions of specialists and consumers, regardless of whether they were people taking it as a medicine or sportsmen wishing to increase the amount of muscle, the described preparation perfectly helps to cope with the problems. And so, despite the fact that the price of Klomiphen tablets is quite high (up to 3000 rubles), the demand for them does not decrease.

But I want to remind you once again: this drug, as well as other medications, in no case can be prescribed to yourself and take without consulting a specialist. You can cause irreparable harm to your health! Be careful and prudent!