The drug "Proflosin": reviews of patients and doctors. Medication "Proflosin": application, composition, reviews

"Proflosin" is a drug intended for use in problems with urination, which are associated with hyperplasia of the prostate gland of a benign nature. This drug is an alpha-blocker.

The active ingredient is tamsulosin, a substance that, acting on the neck of the bladder, reduces its tone, has a relaxing effect on smooth musculature. Such an effect on the body allows you to remove the symptoms of the disease and irritation, adjusts the outflow of urine. The composition contains additional components that enhance the effect of the use of the drug. Consider what the medicine "Proflosin" is. Indications, feedback on its application, effectiveness are presented in the article.

When there are painful sensations when urinating and it seems that the bladder is never empty, while the jet is weak, you need to urgently visit a urologist. Usually such conditions require the use of "Proflosin". Patients' feedback indicates that the drug can be consumed, regardless of the stage at which the disease is located.

Form of issue, composition

The medication is available in the form of capsules, the membrane of which dissolves in the intestine. Capsules are gelatinous, they have a prolonged action. In addition to the active substance, triethyl citrate, a copolymer of methacrylic acid and ethyl acrylate, cellulose, and talc are present in the composition.

Pharmacokinetics, indications

After entering the body, the active ingredient is almost completely absorbed from the digestive tract in a short period of time. This process is disrupted after eating, in such cases it is slower.

As a result of taking the active substance in an amount of 0.4 mg, which corresponds to a single dose, the maximum concentration of the main ingredient in the blood is found after 6 hours.

Reviews about "Proflosin" show that he has a good connection with blood proteins - 99%. The preparation is characterized by an insignificant distribution of 0.2 l / kg. Metabolism occurs in the liver, this task is slow, after its implementation, metabolites are formed. A large part of the drug does not change its shape and enters the blood in an unchanged form.

The active ingredient and substances resulting from its processing are mainly excreted in the urine, while an insignificant part of the drug (9%) is managed from the body in an unchanged form. If the drug was taken after a meal, semi-elimination is done in ten hours, if its use is regular - for 13 hours.

Receipt of the "Proflosin" drug reviews of doctors and patients are allowed for dysuric disorders that develop against the background of prostatic hyperplasia (benign).

Contraindications

The drug is contraindicated for hypersensitivity to its components. Treatment with this drug is not recommended for orthostatic hypotension, even in an anamnesis. Do not take the drug in the presence of arterial hypotension, severe leaking liver failure. If treatment is prescribed to a patient with chronic renal failure, when the CK is less than 10 ml / min, careful monitoring of the physician is required.

Application of the drug, choice of dosage

"Proflosin" reviews patients, the instruction is recommended to be taken once a day. The remedy should be used after the first meal. One capsule must be swallowed without violating its integrity. You need to take good medicine. The division of the capsule into parts can disrupt the rate of absorption of the active ingredient. The course of treatment is not established, the drug is taken as needed, the treatment period is unlimited.

Side effects

There may be abnormalities in the digestive tract, in the nervous system. Possible damage to the reproductive system, heart and blood vessels. During treatment, the remedy can detect changes in the skin and tissues located under the skin.

A man can find problems with ejaculation, in very rare cases, patients develop priapism. Perhaps a significant deterioration of health, when there is a headache, dizziness, sometimes a person is in a pre-memory state.

After receiving the drug "Proflosin" reviews of patients noted that of skin manifestations, angioedema occurs , hives develop, skin itching, an eruption develops. But this happens very rarely. A person can be tormented by diarrhea and constipation. It is likely that side effects will include nausea with vomiting, hypotension (orthostatic), tachycardia.

In a few cases, the narrow pupil syndrome develops as a result of the removal of cataracts, rhinitis, asthenia.

Cases of overdose have not been documented. But theoretically there is such a possibility. When an overdose of the drug may decrease blood pressure, there may be a tachycardia. To normalize the pressure, the frequency of contractions of the heart should lie a little. It is meaningless to assign hemodialysis to the patient, since the active component of the drug binds very well to plasma proteins. It is required to carry out actions that will stop the absorption of the drug - gastric lavage, the use of osmotic laxative or activated carbon.

special instructions

When there are signs of hypotension orthostatic, such as weakness, dizziness, the patient is laid or seated, the necessary manipulations are made.

Before the beginning of therapy, during which it is planned to use the drug "Proflosin", the application, composition, reviews are of primary interest to the patient, but special instructions for its use are also worthy of attention and help to not harm the health even more. When starting therapy, one must be sure that the patient has no conditions, the symptomatology of which is similar to that of the prostate - hyperplasia of benign.

Before treatment and during its implementation, a regular finger rectal examination should be performed, if necessary - determination of PSA level.

With the development of angioedema, the drug is withdrawn and is no longer prescribed. In the presence of cataracts and the operation to remove it, taking "Proflosin" can lead to the appearance of a narrow pupil's syndrome. To exclude such a result, the surgeon must perform a special preoperative preparation, the operation should also be carried out correctly.

When treating with "Proflosin", patients' comments are recommended to be cautious, managing motor vehicles and doing activities that can be life threatening with a decrease in concentration of attention, speed of psychomotor reactions, as dizziness sometimes appears.

Drug Interactions

As a result of taking drugs "Teofillin", "Nifedipine", "Enalapril", "Atenol" there is no interaction with tamsulosin.

With the simultaneous use of the drug with cimetidine, an increase in the level of the active substance tamsulosin in the blood occurs. "Warfarin", "Diclofenac" promote faster removal of tamsulosin from the body. When combining the drug "Proflosin" with similar drugs, it is possible to reduce blood pressure.

When combined with Furosemid, the concentration of the active ingredient of the drug is decreased, however, it is not necessary to increase the dose of Proflosin in this case, since after reduction of the concentration the active substance maintains a normal dose sufficient for therapy with the drug Proflosin. Reviews, instructions, price, description - all this information is important when choosing a specific medication for treatment. Consider the reviews left by doctors and buyers, find out the approximate cost of the drug.

The cost of a medicinal product, analogues

Before using the product "Proflosin" price, instructions, reviews in most cases are carefully studied by the patient. The cost of one pack of capsules is approximately 400-500 rubles.

Of the analogs, we can distinguish "Revokarin" and "Tulosin". Other substitutes for the drug are known, for example, "Fokusin", "Omnik".

Reviews

After reviewing the reviews about the drug, we can talk about its high efficiency. In general, the "Proflosin" is administered by men after 50 years, when prostate disease develops. Many patients are satisfied with the result of treatment, in most cases problems with urination disappear or less painful for a man.

Of the side effects, there are sometimes problems with erection, tachycardia and a decrease in blood pressure. Some patients "Proflosin" did not help, so they had to decide on the operation.

Many doctors choose this medication for treatment only if they are sure that their prescriptions will be strictly observed by the patient. Experts argue that the need for surgery can be ruled out if the patient correctly uses (regularly and at a certain time) the drug "Proflosin". Reviews, instructions, analogs, application, price are now known to you, and, after consulting with a doctor, you can begin treatment. The specialist will conduct the examination and prescribe a certain dose of the medicine, which should help in a particular case.