Medicinal preparation 'Furamag'. Instructions for use, contraindications

"Furamag" refers to the derivatives of nitrofuran antimicrobial agents. One capsule contains 50 mg of active substance furazidine and excipients, talc of potassium carbonate and magnesium carbonate.

Pharmacology

The drug "Furamag" is an antibiotic , it is very resistant to gastric Acid medium, has a high bioavailability, while the color of urine does not change , and its concentration is high in the kidneys. Based on the composition of the drug "Furamag", the instruction refers it to complex means, it consists of furazidine and magnesium carbonate in a ratio of 1: 1, the presence of the latter affects its pharmacological properties.

Furamag acts as a highly effective anti-infectious agent. The fact of its high concentration in the lymph is important, it creates an obstacle for the transmission of infection through the lymphatic ways. The instruction also indicates high concentrations of "Furamag" substance in bile, in slightly smaller amounts - in blood serum, in the liver, in the portal vein. Repeated use of the drug does not cause resistance in microorganisms.

The main principle of the drug "Furamag" is its ability to inhibit nucleic acids. The drug launches in the cell of the microorganism such irreversible processes that inevitably lead to its death. "Furamag" reduces the toxicity of some microorganisms, it is important, because even before its effect leads to their death, there is an improvement in the patient's condition.

The drug "Furamag" has a wide range of action, it shows a high activity in relation to many gram positive and negative bacteria, even to those that remain resistant to other antibiotic drugs. Due to this property, the drug "Furamag" instruction recommends its use. Even in the event that it was not possible to achieve high efficiency from other antibacterial drugs.

To the set of pluses of the drug "Furamag" the instruction adds its beneficial effect on the immune system (unlike other antibiotics that suppress it). The maximum concentration of the drug in the blood is maintained for 8 hours, after 4 hours, you can find the presence of active substance in the urine, the medicine is excreted by the kidneys, there are recommendations for taking after meals, because then the bioavailability of the "Furamag" agent is increased.

Judging by pharmacodynamics, it can be said about the medical indications of the drug "Furamag", first of all it is, of course, severe inflammatory infections caused by microorganisms that show sensitivity to this antibiotic. High efficiency is observed in the treatment of diseases of the genitourinary system, the "Furamag" means for cystitis (chronic or acute), urethritis, pyelonephritis is indispensable.

To the merits of the drug "Furamag" the instruction lists the absence of side effects as opposed to other nitrofurans, only in rare cases nausea with vomiting, neuritis and allergic reactions can be observed.

Contraindications for taking the drug include a special sensitivity of the organism to its components, pregnancy of the patient and the period of breastfeeding. The treatment with Furamag is not recommended for renal failure.

If there is an overdose of the drug, it manifests itself in the form of neurotoxic reactions (it is extremely rare and only in patients with diseased kidneys). In these cases, therapy with enterosorbents, gastric lavage and abundant drinking is recommended.

There are a number of medications that are contraindicated for a number of reasons. These include "Chloramphenicol", "Ristomycin", sulfonamides (oppress hemopoiesis), nalidixic acid (causes antagonism). The drug weakens the effect of other uroantiseptics when combined, acid intake is not recommended.

Storage of the drug "Furamag" is recommended in a dark cool place at a maximum temperature of 25 ° C.