Features of the use of tablets "Clomiphene Citrate"

The drug "Clomiphene Citrate" is an oral antagonist of estrogens, which is part of the group of non-steroid agents. As a result of the use of this drug, the secretion of LH and FSH of the anterior lobe of the pituitary gland significantly increases, the maturation and subsequent growth of the follicles is stimulated. Due to this effect, the "Clomiphene Citrate" agent is prescribed, usually to increase fertility in female patients. In this case, it excellently stimulates ovulation, while blocking the action in the body of estrogens. In addition, it should be noted that this agent does not possess androgenic or gestagenic activity, and in large doses can inhibit the secretion of gonadotropins. The period of the so-called half-life of the drug "Clomiphene Citrate" is about five to seven days.

This oral non-steroidal preparation is available in the form of conventional Medicinal dragee of white color. The main component is a substance such as clomiphene. It is this that effectively reduces the ability of steroid hormones to bind to the corresponding receptors.

Take the tablet "Clomiphen Citrate" instruction recommends for the treatment of anovulatory infertility in women. This drug also helps with dysfunctional uterine bleeding. Women who suffer secondary, disgonadotropic or post-contraceptive amenorrhea, should also start taking this agent - an antagonist of estrogens. The list of main indications for his appointment, in addition to all of the above, also includes polycystic ovary, androgen insufficiency and Chiari-Frommel syndrome. Patients with established galactorrhea, developed against a background of a pituitary tumor, are also often prescribed tablets "Clomiphene Citrate". The reviews also note the positive results of their administration with oligospermia. And, finally, this drug is actively used to diagnose violations of the so-called gonadotropic function of the adipose gland - the pituitary gland.

To prescribe this remedy categorically does not follow if the patient has increased individual sensitivity to clomiphene, as well as in the case of uterine bleeding of unclear etiology. In addition, it is necessary to refrain from taking the drug under consideration in severe form of hepatic or renal insufficiency. The tumor or ovarian cyst is also the reason for refusal in Administration of tablets "Clomiphene Citrate". They are never taken during pregnancy.

In conclusion, it should be said about the main side effects that can be caused by taking the drug. For example, some women may have headaches, insomnia, dizziness, heightened anxiety, depression and fatigue. In addition, there is a risk of visual impairment, cystic enlargement of the ovaries, development of pollakiuria, dysmenorrhea or polyuria, as well as weight gain.