The drug "Duspatalin", instructions for use

The drug "Duspatalin" - myotropic antispasmodic, is produced in hard gelatin capsules of prolonged action, white, opaque. Inside, they are almost white or white granules.

The capsule contains two hundred milligrams of mebeverine hydrochloride and the auxiliary substances: magnesium stearate, talc, ethyl acrylate and methyl methacrylate copolymer in a ratio of one to two, a copolymer of ethacrylate and methacrylic acid in a ratio of one to one.

In the shell - titanium dioxide and gelatin, the composition of ink such - iron oxide black, shellac, soy lentin, antifoaming agent. Capsules are packed in blisters of ten and fifteen.

Pharmacological action of the drug "Duspatalin" instructions for use describes as follows:

It has a direct effect on the smooth muscles of the digestive tract. It is able to eliminate spasms without affecting normal intestinal peristalsis.

Pharmacokinetics of the drug "Duspatalin" an abstract to it describes as follows:

Mebeverin is capable of complete metabolization in the human body. Its first stage is its hydrolysis. The main substance that is formed during the processing of the drug "Duspatalin" in the body is demethylated carboxylic acid. Its half-life is approximately six hours. And the time to reach a maximum concentration of eight hundred and four nanograms, and, consequently, the maximum effect of the drug is three hours.

Mebeverin metabolites are mainly excreted through the kidneys in part in the form of demethylated carboxylic acid. This dosage form has the property of a sufficiently long-term effect, which is evident from its low maximum attainable concentration, the long time to achieve it and the long half-life, while maintaining optimal bioavailability.

Dosage for the drug "Duspatalin" instructions for use gives this:

One two hundred-milligram capsule twice a day, morning and evening about twenty minutes before a meal. Capsules must be swallowed whole, not chewed, and not more than one hundred milliliters of water.

Overdose of the drug "Duspatalin" instructions for use describes this.

In case of an overdose of the medicament, there is an increase in CNS excitability. Treatment in this case consists in washing the stomach and performing symptomatic therapy.

Features of use during pregnancy and lactation of the drug "Duspatalin" instructions for use describes this:

Since there are no clinical data on the treatment of pregnant women, it should be prescribed cautiously and then only if the benefit of providing therapy to a prospective mother outweighs the probable risk to the fetus. And when breastfeeding the drug should not be prescribed.

Side effects with the use of the drug "Duspatalin" are as follows:

Hives, hypersensitivity, exanthema, angioedema.

For the drug "Duspatalin", the application in the instructions is described as follows:

It is shown for the symptomatic treatment of pain, discomfort and discomfort in the intestines associated with the irritation syndrome, treatment of spasms in the digestive tract, even caused by diseases of organic origin.

Contraindications to the appointment of this drug are:

Age to eighteen years, since there is insufficient data on its safety and effectiveness for children, hypersensitivity to the drug and its components.

Special instructions for the use of the drug "Duspatalin" are:

The drug does not affect the ability to drive vehicles and other mechanisms. The conditions under which the drug is released from pharmacies: it can be purchased without a prescription.