"Pangrol 10000": instruction for children, reviews, analogues

What is the purpose of the medicine "Pangrol 10000"? The instructions for use, analogues and indications of the drug will be presented below. Also, you will learn about the dosage the medication is prescribed for children, what is included in its composition, whether it has side effects and contraindications.

Form, description, composition of the medicament

In what form is Pangrol 10000 produced? Instructions, reviews say that this drug is made in the form of opaque gelatin capsules. Their body is orange and the lid is green.

The contents of capsules are small cylindrical tablets. They have an enteric coating, a smooth surface and a beige color.

What substances are a part of the medicine "Pangrol 10000"? The instruction says that the active ingredient of this medicine is pancreatin. Also, the medicament includes additional components in the form of magnesium stearate, croscarmellose sodium, hydrogenated castor oil, colloidal anhydrous silica dioxide and microcellulose.

Features

What is a medicine like Pangrol 10000? The instruction says that this medication is a digestive-enzyme agent. It replenishes the deficiency of enzymes, which are necessary for the normal functioning of the pancreas. Also, this drug produces proteolytic, amylolytic and lipolytic effects.

Operating principle

What is the mechanism of action of the drug "Pangrol 10000"? The instruction indicates that the pancreatin contained in this drug is a powder. It is obtained through the processing of animals of the pancreas (in particular, pigs).

Enzymes contained in it, favorably affect the digestion process. In addition, they accelerate the breakdown of proteins, carbohydrates and fats, help the normal functioning of the pancreas.

In view of the fact that the "Pangrol 10000" (instructions for use for children will be considered below) promotes the digestion of food, it quickly removes all signs of digestive disorders (for example, if there are shortness of breath, a feeling of heaviness in the abdomen, pain, overfilling, flatulence, etc.) .

The intake of capsules stimulates the small intestine, pancreas and stomach to produce enzymes that are directly involved in digestion.

The bile extract, which is part of the medicament, enhances the emulsification of fats, acting on the human body in a choleric manner. This substance increases the activity of lipase, which improves the absorption and digestion of fat-soluble vitamins K, A and E, as well as fats that enter the stomach with food.

Pharmacokinetics

Is Pangrol 10000 absorbed? The instruction says that the capsules are coated with an acid resistant coating. It helps to protect the medicine from gastric juice. As a result, the drug unhindered enters the small intestine. In it, the capsule shell dissolves rather quickly and releases its contents, that is, mini-tablets.

To effectively influence the drug in the small intestine, it is necessary to maintain a slightly alkaline pH level (or neutral).

The medication in question is not absorbed into the digestive tract. It is excreted through the intestine.

Indications for use

What can be used for "Pangrol 10000"? Instructions for use for children and adults indicate that this medication is prescribed, if necessary, for the replacement of exocrine pancreas. In addition, the agent in question is used for an enzymatic deficiency caused by one of the following diseases:

• Syndrome Shvahmana-Diamond;
• Cystic fibrosis;
• Irritable bowel syndrome;
• Narrowing of the pancreatic ducts;
• Presence of gallstones;
• Malignant tumor;
• Intestinal infections;
• Pancreatitis (chronic or acute stages);
• Disorders of the gastrointestinal tract.

For what purposes can Pangrol 10000 be appointed? Instruction for children and adults says that this medication is used as a preparation for x-ray or ultrasound examination of the abdominal cavity. In addition, the capsules are taken to restore the normal functioning of the stomach and pancreas after surgery, as well as in the complex treatment after radiation therapy with symptoms such as indigestion, gas and diarrhea.

Contraindications

Under what conditions can not take the capsule "Pangrol 10000"? Instruction for children, expert reviews report the following prohibitions:

• Acute pancreatitis;
• Hypersensitivity;
• Exacerbation of pancreatitis.

Method of use for young children

In what dose do they prescribe "Pangrol 10,000"? Instruction for children says that the amount of this drug should be determined only by an experienced pediatrician. As a rule, the dosage of the medicine is calculated according to the following scheme: 500-1000 units of lipase per kilogram of the weight of the baby.

The duration of therapy depends on the patient's health status, type and severity of the disease. If the child can not take the whole capsule, then its contents are mixed with water or food that you do not need to chew (for example, porridge or fruit puree). The resulting mixture should be consumed immediately. It is forbidden to keep it.

In the treatment of cystic fibrosis, the volume of the drug also depends on the weight of the child. The initial dosage for babies up to four years is 1000 units of lipase per kg of weight, and for children older than this age, 500 units.

When using the drug in pediatric practice, it is required to follow a strict diet in order to exclude the development of steatorrhoea.

Dosage for adults

Capsules "Pangrol 10000" must be taken with food. They are not chewed, but swallowed whole, washed down with water.

The dose of the medicine is determined by the therapist or gastroenterologist (depending on the patient's condition, form and severity of the disease). As a rule, adults are prescribed two to four capsules a day. If necessary, the doctor can increase the daily dose of the medicine.

Side effects

Against the background of taking this drug in children and adults, such undesirable reactions as diarrhea, nausea, abdominal pain, vomiting, bloating and other disorders of the digestive tract may occur.

Very rarely patients are allergic to the drug "Pangrol". Usually it is expressed in the appearance of urticaria, itching or rash on the skin.

If such effects are found, stop taking the medication and consult a doctor.

Cases of overdose

There are few reviews of the overdose of Pangrol. As a rule, with an increase in the number of enzymes during the treatment of cystic fibrosis, diseases such as hyperuricosuria and hyperuricemia occur.

Special recommendations for admission

Before taking capsules "Pangrol" should always read the attached instructions. It says that during the treatment of cystic fibrosis in people who received large doses of the drug, fibrosing colonopathy (ie stricture of the blind, ileum or large intestine) can develop.

To avoid changes in the symptoms of the underlying disease, before taking this medication it is necessary to undergo a medical examination that will eliminate the presence of intestinal lesions.

The drug in question does not affect the ability of the patient to drive vehicles, nor does it reduce the speed of his reaction while working with dangerous mechanisms.

Analogues and cost of the drug

Today, there is a large number of drugs to improve the pancreas and stomach. Structural analogues of the medicine "Pangrol" are the following: Hermitage, Gastenorm Forte, Pancrelipase, Creon, Enzistal-P, Mezim, Penzital, Mikrazim, Pancreatin Forte, Mezim Forte, Festal, PanziKam, Pancitrat, Panzinorm, Pancreatin-LekT, Pancreatin, PanzimForte, Panzinorm Forte.

As for the price, you can buy 20 capsules of this drug for 250-300 rubles.

Comments of consumers about the drug

Capsules "Pangrol 10000" are very popular among patients. Reviews about this drug are mostly positive. People who regularly take this medicine talk about its quick action and high efficiency.

"Pangrol" significantly improves the process of digestion, thereby eliminating the severity, pain and feeling of fullness of the stomach. Also, thanks to this medicine, you can get rid of excessive gas formation, nausea, heartburn and other unpleasant conditions that occur when taking fat and high-calorie food.

The only drawback of this drug is the difficulty of calculating the dosage, especially for young children. In view of the fact that digestive problems are purely individual, only an experienced doctor can choose the right dosage. This fact significantly complicates the independent use of the drug.