HealthPreparations

The medicine "Tihenam". Instructions for use

The medicine "Tienam", analogues of the drug (means "Grimipenem", "Cilapenem" and others) belong to the category of antibiotic medicines. The active ingredients are cilastatin and imipenem. The latter substance - a derivative of tienamycin - belongs to a new class of carbanemes (beta-lactam type antibiotics). Imipenem inhibits synthesis in the bacterial cell wall, has a bactericidal effect on a wide range of strains of pathogenic Gram-negative and Gram-positive pathogens, as well as on anaerobes and aerobes. Sodium cilastatin - an enzyme of a specific type - inhibits the metabolism of imipenem in the kidneys, substantially increases its level (unchanged) in the urinary tract.

The drug "Tihenam." Instructions. Price. Indications

The cost of the solution for insertion into the muscle is about 500 r, the solution for infusions is from 5000 r. The medicine is prescribed for the treatment of infectious-inflammatory pathologies, provoked by pathogens that are sensitive to it. In particular, the "Tienam" remedy is recommended for use in gynecological infections, lesions in the lower parts of the respiratory system, in the organs of the abdominal cavity. Indications include infectious diseases of the skin, joints, soft tissues, bones, with mixed lesions. In the form of infusions medication is also prescribed for septicemia, endocarditis.

The medicine "Tihenam". Instructions for use

The method of administration and dosage per day are set individually in accordance with the severity of the infection. The total amount of the drug is distributed evenly, taking into account the level of sensitivity of microbes, the activity of the kidneys and the weight of the patient. Intravenous infusion is advisable at the initial stages of therapy of endocarditis, bacterial sepsis and other life-threatening severe infections, including with lesions in the respiratory system, with severe complications, shock conditions. At a weight (on average) of 70 kg and stable renal function, 1-2 g in three to four infusions are prescribed. The maximum allowed to enter a day is no more than 4 g or 50 mg / kg. Intravenous infusion is performed within 20-30 minutes at a dose of less than 500 mg and for 40-60 minutes with a prescription greater than 500 mg. If nausea occurs, the rate of infusion should be reduced. For children from three months with a weight less than forty kilograms, a dosage of 15 mg / kg after six hours. A day is not allowed to enter more than 2 grams. Weighing more than 40 kg dosage as an adult.

The drug "Tihenam." Instructions for use. Contraindications

The drug is not prescribed with increased susceptibility to the components of the agent, to amide anesthetics of local action. Contraindicated in patients with severe shock, pregnant and lactating. The drug "Tienam" instruction for use is not recommended for disorders in intracardiac conductivity. Caution during treatment should be shown with children, elderly patients. If necessary, dose adjustment and infusion rate are adjusted in accordance with the condition.

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