The drug 'Aminazine'. Instructions for use

The drug "Aminazine" is used in medical practice as one of the main antipsychotics for a long time. The use of the drug in therapeutic dosages does not cause drowsiness. The active substance is chlorpromazine.

The drug "Aminazine" instructions for use refers to the derivatives of phenothiazine. The medicine has sedative (sedative) and antipsychotic effects. The use of the drug allows to weaken or eliminate completely hallucinations and delusions, to reduce affective reactions, anxiety, anxiety, motor activity (psychomotor agitation). Taking high doses of the drug "Aminazine" (overdose) can cause drowsiness, depression, extrapyramidal disorders. The drug is also able to increase the secretion (secretion) of prolactin.

Characterizing the drug "Aminazine", the instruction for use indicates its antihistaminic, alpha-adrenoblocking and weak m-cholinoblocking activity. The drug is able to lower blood pressure.

The mechanism of the central action of the remedy is associated with blockade in various areas of the brain of dopamine receptors. The soothing effect is probably based on blockade in the central adrenoreceptors.

Getting inside, the medicine is quickly absorbed from the digestive system. Excretion is carried out mainly with feces and urine. The elimination half-life is very long (from four weeks and more).

The drug "Aminazine" instructions for use recommends for conditions of hallucinatory-paranoid and paranoid chronic course, psychomotor excitation in the background of schizophrenia (with catatonic, hebephrenic, hallucinatory-delusional syndrome).

The drug is indicated for alcoholic psychosis, neurotic pathologies complicated by increased muscle tone, to alleviate pain, including, causalgia (burning pain) in combination with pain medication.

The drug is prescribed for persistent sleep disorders (in combination with tranquilizers and sleeping pills), mental disorders against the background of epilepsy, manic agitation and agitated depression in manic-depressive psychosis.

The drug "Aminazine" instructions for use allows for the appointment of vomiting pregnant women, Meniere's disease, itching dermatoses. The drug is used in anesthesiology. In addition, the medication is indicated as the prevention and treatment of vomiting against the background of therapy with antitumour agents, with radiation therapy.

Dosing regimen is determined for each patient individually.

Usually the daily intake of adults is not more than one and a half grams, once it is allowed to take no more than 300 mg. For children, the amount of the drug is prescribed at the rate of one milligram per kilogram of weight.

Taking medication can trigger a number of adverse reactions. The most likely negative effects are dyspepsia, tachycardia, hypotension, dry skin.

The drug "Aminazine" is contraindicated in brain trauma, coma, in the late phase of bronchiectasis, thromboembolism, decompensated cardiac malformations. Do not prescribe a remedy for myxedema, progressive pathologies in the brain or spinal cord, disorders of kidneys, liver, hematopoiesis.

special instructions

If the patient is prescribed to take the drug "Aminazine" (in tablets or injections) at home, then after use it is recommended to stay in a horizontal position for at least one and a half hours. Do not make sudden movements. This is due to the ability of the drug to lower blood pressure.

The drug "Aminazine" is not intended for use by patients independently.