Tablets Sildenafil: instructions for use, price and reviews of the drug. Is Sildenafil effective for women?

Preparations based on sildenafil are vasodilators acting on the cavernous body, which is located in the human genital organs. The greatest effectiveness of this group of drugs showed in the treatment of erectile dysfunction in men, as well as in the normalization of a natural reaction to sexual arousal. As a medicinal product, sildenafil is also used to treat pulmonary hypertension. The most famous drug containing sildenafil, reviews about which in the majority only positive, is "Viagra". The rest of the funds are created using the same components, but they are much cheaper. Such drugs are called generics.

The most frequently asked question for consumers of such drugs is where to buy sildenafil? After all, in online pharmacies and online stores, there are many stimulating and supporting drugs, in which this substance is mentioned. Which of them do contain sildenafil? How much does each of these funds cost? Can I use these drugs for women? For all these questions, every consumer wants to hear a clear and extremely clear answer.

Preparations containing sildenafil - what's the difference?

To date, in the Russian pharmaceutical market, there are many drugs containing sildenafil. Analogues, the price of which in some cases is slightly lower than that known to all "Viagra", are in great demand among buyers. Names of medicines do not always contain the name of the active substance. In the available sale, you can find the following synonyms of sildenafil: Viagra-LF, Silafil, Sildenafil with Dapoxetine, Sildigra, Sukhara, Sildenafil Ratiofarm, Edera, Tornetis, Revazio, "Cialis" and many others.

The different name of the tablets does not at all mean that they belong to preparations with a different chemical composition. What, besides the names, are the preparations containing sildenafil different from each other? Price is the first thing that any consumer pays attention to. The most expensive is considered the original "Viagra", patented in the last century. The cheaper analogs produced in Poland, Ukraine, India and other countries contain an absolutely identical amount of active substance. The lower cost is due to the use of cheaper auxiliary components, as well as production conditions.

The "sildenafil" tablets produced in Croatia are considered to be the most "pure" in terms of the content of impurities. The greatest number of different impurities is contained in drugs produced by pharmaceutical companies in India. However, it is worth taking into account that the amount of extraneous inclusions in the active substance practically does not affect the effectiveness of the drugs.

Composition of preparations

The main active ingredient of preparations similar to Viagra is sildenafil citrate in a dosage of 25, 50 or 100 mg in one tablet. Additionally, each tablet contains auxiliary substances: lactose, titanium dioxide, triacetin and indigocarmine, which gives the tablets a distinctive blue color. Sildenafil tablets most often look like a biconvex lumbar pale blue.

Analogues of "Viagra", or the so-called generics produced by Indian pharmacists, can take the form of tablets that do not require washing or jelly with a variety of tastes. These forms of drugs are convenient to use, since they begin to be absorbed already in the oral cavity, because of which their action occurs much earlier than that of "Viagra."

Pharmacological properties of sildenafil

The pharmacological properties of preparations containing sildenafil are based on its ability to interact with natural enzymes that are directly involved in filling the blood of the penis, namely with cyclic guanosine monophosphate. This enzyme stabilizes the amount of nitric oxide supporting the vessels of the penis in the expanded state. Sildenafil interferes with the cleavage of cGMP by other enzymes, so that the erection becomes longer and more stable.

It should be noted that in the case of the use of the drug "Sildenafil" instructions for use warns of the need for sexual arousal, since the drug does not have the ability to independently initiate blood flow to the cavernous or cavernous bodies in the penis. That is why to achieve the result it is necessary to conduct sexual stimulation of a man, which will cause an erection. Absence of stimulation can mean complete absence of swelling of the penis.

In addition to the male version, there are similar drugs for their partners. Sildenafil for women (produced under the names Womenra, Femalegra, Ladygra, Cenforce FM) is used as a therapeutic agent, whose action is aimed at filling the blood of the pelvic organs, which increases the sensitivity of the genital organs. Due to this property, the amount of vaginal lubrication increases, the orgasm increases and lengthens, and a tendency to prolonged sexual intercourse appears. Sildenafil for women acts more strongly, therefore in many cases special stimulation is not required.

Medicines based on sildenafil are used to treat erectile dysfunction in men. Due to the fact that the active substance effectively affects the blood vessels in the body, there are a number of indications and contraindications to its use.

Indications for use

The active substance is effective in organic, psychogenic or mixed types of disorders. To accept sildenafil the instruction on application advises and at absence of an erection in connection with age changes in an organism. In addition, the remedy is active with a weak erection caused by diseases such as obesity, metabolic disorders, including type 1 or type 2 diabetes, the absence of the prostate gland due to its removal, a back injury with spinal cord injury.

Contraindications for use

Concerning contraindications to the drug "Sildenafil" instructions for use contains a fairly extensive list of diseases and concomitantly taking medications, in which use of the drug should be limited or eliminated completely.

A complete withdrawal from the drug is necessary in such cases:

• The presence of diseases of the cardiovascular system - aortic stenosis, heart failure, angina, cardiomyopathy, as well as within 6 months after a heart attack or stroke.
• Impaired vision is ischemic optic neuropathy, retinitis pigmentosa and other retinal pathologies.
• Complicated liver disease - hepatitis, cirrhosis.
• Reduced blood pressure (within 90/50 mm Hg) or increased (more than 170/100 mm Hg).
• Intolerance to sildenafil or other components that make up the medicines.
• Sildenafil should not be taken with other drugs such as Nitroglycerin, Vasotropin, Molsidomine, Erythromycin, Clarithromycin, Nefazodone, Iloprost.

Relative contraindications to the use of drugs containing sildenafil, the instruction for use calls the following conditions:

• Diseases of the hematopoiesis and circulatory system - leukemia, thrombocytopenia, sickle-cell anemia.
• Deformation of the penis - Peyronie's syndrome and angulation.
• Peptic ulcer of gastrointestinal tract in the stage of exacerbation.

How to take sildenafil with erectile dysfunction

Preparations containing sildenafil, the instruction recommends to drink orally, squeezed with enough liquid. Dosage at the first intake of medications on the basis of this active substance should be 50 mg. Depending on the reaction of the body in subsequent receptions, it is possible to adjust the dose of sildenafil to a greater or lesser extent. It should be taken into account that the maximum dose, being safe, is 100 mg.

Take the sildenafil instruction advises an hour before the alleged sexual intercourse. A one-time admission of 25, 50 or 100 mg of the drug is considered possible in all age groups, ranging from 18 years. It is not recommended to independently increase the dosage of drugs to people who are in advanced age and experience an age-related decline in muscle tone of the whole body.

Depending on the metabolism and on the existing concomitant diseases, there is a scheme for taking sildenafil, which provides for the adjustment of the dose of the drug for one dose. If the kidney function is impaired with a glomerular filtration factor not exceeding 30 ml per minute, the maximum allowable dose of sildenafil 25 mg is recommended. With functional disorders in the liver and gall bladder, the maximum permissible single dose of the drug should not exceed 25 mg.

When taking medications containing sildenafil, instructions for use, testimonials indicate that this absolutely does not affect the ability to drive a car and other means of increased danger. In very rare cases, consumers could observe violations of color perception and a slight decrease in blood pressure. These side effects occur in most cases when the recommended dose is exceeded or after the first medication.

With a noticeable deterioration in hearing or vision (partial or complete deafness, noise and ringing in the ears, which lasts for several hours after the application of the remedy), it is necessary to stop taking sildenafil.

The rules for taking sildenafil with pulmonary hypertension

As a drug, sildenafil can be used in any form of pulmonary hypertension. Take the drug is recommended three times a day, the dosage of the drug is 25 mg per each dose. Interruptions between taking each tablet should be at least 6 hours. This treatment regimen is effective in the treatment of pulmonary arterial hypertension at any age.

Regarding contraindications and restrictions on the use of the drug "Sildenafil" the instruction says that, with the existing disorders from the organs of urination and digestion, it is shown to reduce the daily dose of the drug to 50 mg, dividing it into two receptions.

Joint use of sildenafil with other drugs

Like any other medications, sildenafil is recommended to be taken separately from other drugs, since simultaneous ingestion of incompatible medicines in humans may not give a positive reaction.

There are several groups of drugs, with the interaction with which drugs based on sildenafil can change their properties. Little or no negative effect on the body, along with sildenafil antacids, antidepressants, diuretics, hypotensive drugs. With the simultaneous administration of sildenafil with adrenoblockers, there may be a drop in blood pressure to critically low rates. In addition, the drug sildenafil enhances the effect of "cardiac" drugs, such as nitroglycerin and sodium nitroprusside. With their simultaneous use with antibiotics of the tetracyclines and erythromycins, prolongation of the action time of sildenafil is observed.

Side effects of sildenafil

The development of side effects of preparations based on sildenafil citrate directly depends on the dose taken. Side effects are usually expressed in mild or moderate form, and the signs and symptoms of various disorders go away on their own, without the use of any therapeutic means.

In order to avoid the occurrence of excessively intense reactions to the use of drugs containing sildenafil, manufacturers provide all the necessary dosage data, which is unsafe to exceed.

Sildenafil - reviews

Reviews about sildenafil are mostly positive, but the drug is not considered experts as a panacea for any erectile dysfunction. A positive effect was achieved in 80% of patients taking sildenafil. The price of drugs in this group also caused a lot of positive responses. A wide choice of analogues of Viagra allows you to buy drugs for people with an average or low level of income. The largest number of respondents named Sildenafil Severnaya Zvezda as the most accessible means, which can not be called negative feedback.

The greatest number of positive responses sildenafil received from men who used it as a safety net, because they felt insecure in their own abilities. The effect they said lasted at least 4 hours after taking the drug, and a steady erection occurred in everyone in different ways - from 30 minutes to an hour after taking the pill. Single cases of unstable erection were noted after taking the recommended initial dose of 25 mg. However, after repeated use of an additional dose of 25 mg, a persistent erection was initiated within 4-5 hours.

In addition to other phenomena that affect the potency of drugs containing sildenafil, an instruction on the use, the price of which satisfied consumers in full, there are many other aspects of the evaluation of the effectiveness of the drug. For example, reviews about the compatibility of the drug with alcohol are not so unambiguous. About 50% of the men surveyed noted the absence of negative effects of moderate doses of alcohol on the effectiveness of the drug, about the same number of men noticed an erection weakening. In addition, the achievement of maximum effect in more than half of men was delayed due to "seizing" funds with a lot of fatty foods.

Concerning the occurrence of side effects of men in the reviews of sildenafil, the most often mentioned minor headache and reddening of the face. In addition, half of the respondents noted the appearance of nasal congestion and minor nosebleeds. However, this did not become an excuse for refusing to use sildenafil, since the effect from it pays back these minor inconveniences.

From women who took sildenafil (instructions for use, the price for most are quite acceptable and understandable), received extremely positive and sharply negative reviews. About 48% of the polled representatives of the weaker sex were satisfied with the effect of the drug, but noted that after some time after receiving it, they had abdominal pain and upset of the stool.

Cost of preparation

A very significant dispersion in the prices of drugs from the group sildenafilsoderzhaschih funds due to the country in which the drug was produced. If the original agent "Viagra", which includes sildenafil, the price in most pharmacies is about 800 rubles for one tablet of 100 mg, then analogues can be purchased several times cheaper. Sometimes the difference in the cost of such drugs reaches several hundred rubles. Regarding preparations containing sildenafil: how much is each of them, you can see in the following table.

Regarding the quality and effectiveness of other drugs, which includes sildenafil, reviews suggest a slight difference with the original. Despite the less pronounced effect, generics are popular with many, because they are more affordable.

Where to buy drugs based on sildenafil?

There are two options for buying sildenafil: through online stores and in regular pharmacies. Whichever way you choose, there is a danger of getting a fake, especially for online pharmacies, because pharmacy shops that are familiar to everyone can check the quality of drugs themselves after receiving complaints from customers. That is why it is important to check the information about the seller before making a purchase. To do this, it is enough to pay attention to the section "reviews" on the Internet resource where they sell the tool, or to search information in various forums.

To date, there is an opportunity to send the purchased medicine for examination, where the exact composition of the drug will be established, as well as information on its safety for the consumer. To do this, you need to purchase the minimum amount of funds in any pharmacy and contact the laboratory. The analysis is carried out within a day, a maximum of two. If you confirm the proper quality of the drug, you can buy a drug based on sildenafil in the same pharmacy.