"Fortum": instructions for use. Price, description, reviews, analogues of the preparation

Why do I need Fortum? Instructions for the use of the product, its composition, packaging and form of release will be presented in this article. Also from it you will learn about what this medication is, what side effects and contraindications it has, whether it has analogs for this drug, and how much it costs.

Composition, packaging and form of release

How can I get a Fortum medical device? The medicine we are considering is sold in the form of a powder. It is used to prepare an injection solution. 1 bottle of the drug contains an active element, such as ceftazidime (in the form of pentahydrate). As for minor components, they include anhydrous sodium carbonate and carbon dioxide. One bottle contains 1 bottle.

Pharmacological characteristics of the drug

What is the "Fortum" medication? Instruction for use states that this is a third generation cephalosporin antibiotic. It has a bactericidal effect. Getting inside the body, the drug disrupts the synthesis of the cell walls of microorganisms.

The drug has a broad spectrum of action (in particular antimicrobial). It kills strains of pathogens that are resistant to gentamicin, as well as to other antibiotics belonging to the group of aminoglycosides. However, I want to note that this drug is resistant to the effects of most beta-lactamases.

As a result of the studies, it was found that the active substance of the drug is active against a variety of gram-positive, gram-negative and anaerobic bacteria, including strains that are resistant to ampicillin.

It should also be noted that ceftazidime is not active against methicillin-resistant staphylococci.

Pharmacokinetics of the drug

How fast is Fortum? Antibiotic after intramuscular or intravenous administration in dosages of 1 g and 500 mg is very quickly detected in blood plasma. In this case, the therapeutic concentrations of the active element remain approximately 8-13 hours. As for the connection with proteins, it is about 10%.

Active substance concentrations exceeding the MIC for the most part of common pathogenic bacteria can be achieved in bile, bone tissue, sputum, heart tissues, synovial, pleural, intraocular and peritoneal fluids.

I also want to say that ceftazidime quite easily penetrates the placental barrier, and also stands out together with the mother's milk. In the absence of inflammatory processes in the meningeal shells, the active element of the medication penetrates bad enough through the BBB. The concentration of the agent in the cerebrospinal fluid is very low.

The drug in question is not metabolized in the human body. The half-life of the drug is about 2 hours. Ceftazidime is excreted in urine in unchanged form.

It should be specially noted that if the kidneys are disturbed, the rate of excretion of the active substance is markedly reduced.

Indications for use

In what cases is the medicine "Fortum" prescribed? Instructions for use include the following list of indications:

• Infection in people with cystic fibrosis, as well as with respiratory infections;
• Severe infections, including nosocomial (peritonitis, septicemia, meningitis, bacteremia, infected infections and infections in people with low immunity);
• Infections of the nose, throat and ears;
• Infections of soft tissues and skin;
• urinary tract infections;
• Infection of joints and bones;
• Infection of the gastrointestinal tract, biliary tract and abdominal cavity;
• Infections that are associated with dialysis.

Also, the drug is actively used to prevent infectious complications after surgery on the prostate gland.

Contraindications to use

When should I not prescribe Fortum? Instruction for use contains the following list of contraindications:

• Increased sensitivity of the patient to ceftazidime, as well as other elements of the drug;
• Newborn children;
• Increased sensitivity of the patient to cephalosporin antibiotics and penicillins.

It should also be noted that this drug with particular caution is prescribed to people with kidney failure, gastrointestinal diseases, pregnancy, lactation, in combination with aminoglycosides and diuretics.

Instructions for use of the medicinal product

How should I correctly apply the medicine Fortum? The injections are administered to patients on an individual basis. Their dosage depends on the severity of the course of the disease, as well as localization, sensitivity to the drug, the type of pathogen, the age of the patient and the function of the kidneys.

The medication is administered intravenously or deeply intramuscularly (in the lateral part of the thigh or the outer upper quadrant of the gluteus maximus muscle). Also, the infusion solution can be introduced into the tube of the system.

The daily dosage of the drug (maximum) is about 6 g. Adults are prescribed 1-6 g per day intravenously or intramuscularly. Multiplicity of drug administration - 2-3 times a day.

Most often, the medication in question is administered 2 g at intervals of 12 hours or 1 g every 8 hours.

If the patient has a severe course of the disease and a decreased immunity, and there is also neutropenia, then he is prescribed 2 g of medication every 8 or 12 hours. Also, 3 g of the drug can be administered every 12 hours.

As with infections of the lung and urinary tract infections apply the drug "Fortum"? Analogues of the drug and the medication itself are administered in a volume of 1 g or 500 ml every twelve hours.

To treat infectious complications with such a deviation, as cystic fibrosis, the drug is used in an amount of 100-150 mg per kg per day (divide by 3 times).

In surgical intervention on the prostate gland, the medication is used in a dosage of 1 g with anesthesia, and the second dose is administered during removal of the catheter.

Elderly patients (especially people older than 80 years), the drug is prescribed in a volume of not more than 3 g per day.

Children over 2 months of medication prescribed at a dosage of 30-100 mg per kg per day. Moreover, the frequency of administration is 2-3 times.

Children with meningitis, low immunity or cystic fibrosis are prescribed up to 150 mg per kg per day. The maximum dose is 6 g (divided by 3 times).

Infants and newborn children under the age of two months of the drug is prescribed only in certain cases. At the same time, its volume should be 25-60 mg per kg per day (divided in half).

People with renal insufficiency need a lower dosage of the drug, since ceftazidime is excreted by the kidneys unchanged. The initial dosage for such patients is 1 g. As for the supporting volume, it is selected individually (depends on the speed of glomerular filtration).

Overdose

It does not matter, expensive or cheap drugs you use to treat infections. In any case, they should only be used as directed by the doctor.

If the antibiotic in question was used in an increased volume, then you risk receiving the following overdose symptoms: neurological disorders, including convulsions, coma and encephalopathy. As a treatment for such conditions, doctors recommend conducting symptomatic and supportive therapy.

Side effects of the drug

Cheap medicines, along with expensive antibiotics, have a fairly large number of side effects. Let's consider their list.

• The digestive tract: nausea, candidiasis of the pharynx and oral cavity, jaundice, diarrhea, abdominal pain, vomiting, and also transient increase in the activity of GGT, LDG, AST, ALT and APF. In addition, as with other cephalosporins, this drug can cause pseudomembranous colitis.
• Central and peripheral nervous system: paresthesia, headaches, dizziness, flawed sensations, neurological disorders, including tremor, convulsions, myoclonia, encephalopathy and coma.
• The hemopoietic system: leukopenia, eosinophilia, lymphocytosis, neutropenia, thrombocytopenia, agranulocytosis, hemolytic anemia and thrombocytosis.
• The urinary system: a disruption of the kidneys, a transient increase in urea, and urea nitrogen and creatinine in the blood.
• Allergies: lowering of blood pressure, maculopapular rash, fever, urticaria, bronchospasm, itching, angioedema edema, exudative erythema multiforme, including Stevens-Johnson syndrome, epidermal toxic necrolysis (i.e., Lyell's syndrome).
• Local adverse reactions: thrombophlebitis or phlebitis (with intravenous administration), compaction at the site of intramuscular injection, pain and burning.
• Others: direct Coombs reaction (false positive) and candidal vaginitis.

Interaction with other drugs

Is there a list of drugs with which Fortum can or, conversely, can not be used? It should be noted that there is no definite list. However, before using this remedy, it is absolutely necessary to read the instructions, or rather the section "Drug Interactions". From it you will learn that the simultaneous use of ceftazidime in high dosages and nephrotoxic medicines can have a negative impact on kidney function.

Diuretics, vancomycin, aminoglycosides and clindamycin significantly reduce the clearance of the active substance of the drug, which increases the risk of nephrotoxic exposure.

Bacteriostatic antibiotics, including the drug "Chloramphenicol", reduce the effect of beta-lactam antibiotics.

The "Fortum" medication is compatible with almost all solutions for intravenous administration. Although it should be noted that ceftazidime is not stable in a solution of sodium bicarbonate. In this regard, this substance is prohibited to use as a solvent.

Instructions for the use of medicament

What do I need to know before using Fortum? The action of antibiotics can adversely affect the health of patients. If the patient has an allergic reaction, then the drug must be canceled.

Long-term use of this medication may contribute to an increase in the growth of insensitive bacteria. In this case, treatment may be discontinued.

Medicinal product "Fortum": analogues and cost

It is rather difficult to call the drug under consideration cheap. So how much is the "Fortum" medication? The price of it can be different and depend on the dosage of the medicine. A bottle of 500 ml can be purchased for 196 Russian rubles, and 1 g and 3 g - for 452 and 626 rubles, respectively.

Consider a list of medicines, the action of which is similar to the drug "Fortum":

• "Vitsef";
• Bestum;
• "Kefadim";
• "Kefadim";
• Orzid;
• Laurazidim;
• "Tizim";
• Fortazim;
• "Tazitsef";
• "Ceftazidime";
• "Cephzid";
• "Ceftidine."

Reviews about the medicine

What do patients say about the "Fortum" preparation? The price of them is quite satisfactory. Moreover, most patients claim that the antibiotic in question is very effective. Although there is such a category of patients, to whom it is not suitable because of the large number of side effects.