Exoderil. Instructions for use

"Exodermil" goes on sale as a solution or cream and is an antifungal drug. The active substance of the drug is naftifin hydrochloride. Auxiliary substances of the solution are: purified water, propylene glycol, ethanol. Excipients of the cream are sodium hydroxide, sorbitan stearate, benzyl and cetyl alcohols, cetyl palmitate, stearyl alcohol, isopropyl myristate, polysorbate 60, purified water. For local treatment of dermatophyte stops, inguinal and other dermatomycosis (fungal infections), "Exoderil" is prescribed. The instruction on the preparation shows that naphthyfin hydrochloride has fungicidal activity against a wide range of microorganisms: Trichophyton mentagrophytes, Trichophyton rubrum, Epidermophyton floccosum, Trichophyton tonsurans, Microsporum canis, Microsporum gypseum and Microsporum audouini, and fungistatic activity against Candida species, including Candida albicans.

Naphthyfine hydrochloride is a synthetic derivative of allylamine. The exact mechanism of action of naftifin hydrochloride is unknown. There is an assumption that it can selectively block the biosynthesis of sterols. This inhibition leads to a decrease in the amount of sterols, especially ergosterol, as a result of which the integrity of the cell is impaired. So the pathogenic fungus is destroyed by the drug Exoderil. The instruction reports fungicidal activity against dermatophytes (Trichophyton, Epidermophyton, Microsporum) and mold fungi (Aspergillus), as well as pathogens of sporotrichosis. Also, the drug "Exoderyl" shows antibacterial effects on various microorganisms, often associated with fungal lesions.

"Exoderm" has a prolonged (up to 24 hours) anti-inflammatory effect, reducing itching. Half-life is approximately 2-3 days. Metabolites are excreted in urine and feces. In the form of a solution (1%) or cream (1%), the drug "Exoderyl" is used. The instruction recommends applying it in a thin layer on the infected surface and around it. To do this, thoroughly rub once a day with a massage massage on carefully cleaned and before use the dried areas. With dermatomycosis treatment lasts 2-4 weeks, with candidiasis - from 4 weeks. Then the treatment can be extended up to 6-8 weeks.

In the absence of clinical improvements after 4 weeks of use, it is recommended to seek medical advice and clarify the diagnosis, the doctor can replace "Exoderil." The instruction gives an idea of the complexity of the treatment of nails: with onychomycosis (damage to the nail plate by pathogenic fungi), the solution or cream is applied twice a day to a sore spot, covered with a dense bandage, the course lasts a full 6 months. With a complicated form of lesion - up to 8 months. After achieving clinical improvements, treatment continues for weeks 2 to avoid relapse.

For skin infections such as mycosis, pruritus and ringworm, the Exederil drug is effectively used. Analogues of it have the trade name "NAFTIN", the active substance of which is also naftifina hydrochloride. Analog "Exoderil" is available in the form of 2% cream and gel. They are designed for external use. The cream has a white or yellowish color. Each gram of the drug contains 20 mg of naftifin hydrochloride. The cream is usually used once a day, and the gel twice a day in the morning and in the evening from 2 to 4 weeks. Some infections require an increase in treatment to 6 weeks. When using the drug, you should follow the doctor's recommendations and follow the instructions of the instructions: you can not use less often or more often than prescribed by your doctor.

Side effects are only of local importance. They can cause a cream or "Exoderyl" solution. Reviews and instructions equally describe the possible symptoms: itching, burning, redness, dryness, rash. If these problems occur, consult a doctor. Also, before starting treatment, tell your doctor about the allergy to naphthyfine hydrochloride or any other ingredients that make up the drug. In addition, the doctor should be informed about those drugs or vitamins that the patient is taking or they are only assigned to him. It is also necessary to remember the contraindications for pregnant and lactating women.