Contraceptive pill "Belara": reviews of doctors, pros, cons, contraindications, doctor's recommendations

Is the medicine "Belar" effective? Reviews of doctors (pros, cons) will be presented below. Also you will learn about the form in which this preparation is manufactured, what ingredients it contains, whether it has contraindications to administration and side effects.

Description, composition, shape, packaging

The drug "Belara" goes on sale in the form of round biconvex light pink tablets with a white core. It includes active ingredients such as chloromadinone acetate and ethinylestradiol. It also contains additional ingredients in the form of lactose monohydrate, povidone, corn starch and magnesium stearate.

As for the pink film shell, it consists of titanium dioxide, talc, hypromellose, lactose monohydrate, macrogol 6000, propylene glycol and red iron oxide dye.

On sale, the agent in question comes in blisters, which are contained in a box of cardboard.

Pharmacodynamics

What is the drug "Belar"? The doctors' comments (pluses, minuses of the drug will be presented later) say that this is a combined contraceptive intended for oral administration.

Prolonged use of tablets reduces the secretion of lyutenizing and follicle-stimulating hormones and, as a consequence, suppresses the process of ovulation. Also, this drug promotes proliferation and secretory transformation of the endometrium. Such an effect prevents the fixation of a fertilized egg.

When taking this medication, the viscosity of the mucosal secretions from the cervix increases. Due to this, male sex cells with difficulty pass through the female genital organs.

The chloromadinone acetate included in this preparation is a gestagen that has antiandrogenic properties. It is able to compete with androgens in specific receptors and thereby weaken their effect.

The probable onset of pregnancy for the year varies between 0.29-0.69%, and depends on strict adherence to the dosing and medication regimen.

Pharmacokinetics

The "Belara" tablets contain two active substances. Their kinetic parameters vary considerably:

• Chlormadinone acetate is quickly and completely absorbed from the digestive tract. Its highest concentration in the blood is observed after an hour and a half. About 95% of the substance binds to plasma proteins (mainly with albumin).

When the component is transformed, several metabolites are formed (3-alpha and 3-beta-hydroxy-chloromadinone acetate).

The half-life of this element is 33 hours. Chlormadinone acetate, as well as its metabolites, are excreted in equal quantities together with urine and feces.

• Ethinyl estradiol is also rapidly and completely absorbed from the intestine. Its highest concentration in plasma is achieved after 90 minutes. Absolute bioavailability of this substance is 40%.

Approximately 98% of ethinyl estradiol binds to blood proteins. It is transformed by hydroxylation of the aromatic ring. The main derivative of this substance is 2-hydroxy-ethynyl estradiol.

The half-life of the component under consideration is 13 hours. It is deduced with feces and by means of kidneys in the ratio of 3: 2.

To completely block ovulation, chloromadinone acetate should be taken in an amount of 1.7 mg every day. The dosage for the full cycle is about 25 mg.

Indications for use

Tablets "Belar" are intended only for women. They are necessary for oral contraception.

Contraindications

Under what conditions can not take medication "Belar"? Reviews of doctors (pluses, minuses of this remedy should be taken into account by all women) report that this drug can not be used with:

• Thrombosis and thromboembolism (pulmonary embolism, myocardial infarction, vein thrombosis, cerebrovascular changes);
• Planned operative intervention (one month before), and also during the period of immobilization;
• Uncontrolled arterial hypertension;
• Initial signs of thrombosis or thrombophlebitis, as well as with symptoms of embolism (including temporary ischemic attacks);
• Acute or chronic severe liver damage;
• Uncontrolled diabetes mellitus;
• Itching of the whole body, cholestasis;
• Predisposition to the appearance of arterial and venous thrombosis;
• Severe pain in epigastrium, hepatomegaly, or signs of intra-abdominal hemorrhage;
• Liver tumors;
• Migraine attacks;
• Syndrome of Rotor or Dubin-Johnson, as well as slowing down the outflow of bile;
• Motor disorders;
• Sensory violations of an acute nature;
• Porphyria;
• Hormone-dependent malignant tumors or suspicion of them;
• Severe depression;
• Pancreatitis;
• Cryptogenic amenorrhea;
• Pronounced changes in lipid metabolism;
• During lactation;
• Increased frequency of epileptic seizures;
• Pregnancy;
• Complicated otosclerosis, including during previous pregnancies;
• Predilection for smoking (patients aged 35 years);
• Endometrial hyperplasia;
• Lactose intolerance, lactase deficiency and glucose-galactose malabsorption;
• Vaginal bleeding of unknown origin;
• The presence of a variety of risk factors for venous or arterial thrombosis;
• Sensitization to drug substances.

How to drink the contraceptive pill "Belar"?

According to the instructions, the birth control pills should be taken orally, without chewing and washing with a small amount of water. How should I take a reception? "Belara" must be taken every day at the same time (in the evening).

The duration of the drug is 21 days. Then it must be interrupted for a week. About 2-4 days after the last pill, menstrual bleeding is observed.

After seven days, you need to start taking the drug from another pack, regardless of whether the bleeding has stopped or not.

The first tablet should be used on the 1st day of the physiological cycle (that is, on the first day of the next menstruation). Only in this case, contraception begins its operation and lasts even during a one-week break.

However, the first tablet can be taken on the 2nd-5th day of the menstrual cycle. In this case, barrier methods of contraception should also be used during the first 7 days.

If the menstruation began more than 5 days ago, then you must wait for the beginning of the next, and only then proceed to the cycle of taking the tablets.

Side effects

Now you know how to drink birth control pills. It should also be taken into account that taking this medication can cause the following side reactions:

• Nervousness, irritability, depressed mood, weakening of libido;
• Increased appetite, changes in fatty blood composition;
• Hypersensitivity to the components of the drug;
• Intolerance to contact lenses, visual disturbances, conjunctivitis, tinnitus, hearing loss;
• Dizziness, migraine headaches;
• Thrombosis of veins, pressure increase, collapse, arterial hypotension, varicose veins, arterial hypertension;
• Flatulence, abdominal pain, nausea, diarrhea, vomiting;
• Hyperhidrosis, acne, erythema, chloasma, urticaria, hair loss, pigmentation disorders, eczema;
• Lumbodynia, feeling of heaviness, muscle disorders;
• Vaginal candidiasis, dysmenorrhea, vulvovaginitis, increased vaginal discharge, premenstrual syndrome, amenorrhea, fibroadenoma of the breast, lower abdominal pain.

Drug Interactions

Is it possible to combine the contraceptive "Belara" with other drugs? The use of these tablets with others can weaken their effect. Such suppressive drugs include:

• Substances that activate microsomal hepatic enzymes;
• Agents that enhance intestinal motility;
• Some antibiotics.

After the "Belara" and the use of these funds, additional methods of contraception should be used.

Price and analogy

Analogues of the drug in question are the following: "Vidora", "Daila", "Jess", "Diphenda", "Jeanine", "Lindineth 20", "Logest", "Mersilon", "Milanda", "Modell Tin", "Novinet "," Silest "," Femoden "," Yarina Plus ".

As for the price, it directly depends on the number of tablets in the package. The average cost of the drug "Belar" is 490-530 rubles (21 pcs.).

"Belara": reviews of doctors (pros, cons)

According to specialists, the drug "Belara" has established itself as a very reliable contraceptive. When it is properly administered, an unwanted pregnancy is excluded. However, this drug also has negative feedback. Doctors report that it can cause a large number of side effects. This medication promotes a set of excess weight, and is also very harmful to the skin. Moreover, he has an impressive list of contraindications.