Anti-inflammatory and analgesic preparations

Among all medicines sold by pharmacists, the greatest demand is for painkillers. Such medications are able to relieve spasm. They eliminate the production of prostaglandins - the causative agents of unpleasant sensations. Also, the drugs have a pronounced anti-inflammatory effect. Especially often, consumers use nonsteroidal painkillers. You can buy them without a special recipe. The task of such means is to reduce the temperature, stop the pain and inflammation. Painkillers are also used for osteochondrosis, trauma and (only some) after surgical interventions. Let's consider in more detail, what medicines happen and what are their features.

Acetylsalicylic acid: a proven tool for adults

This drug, used as an analgesic, belongs to the group of non-steroidal anti-inflammatory drugs. The active substance here is acetylsalicylic acid. This component has a pronounced analgesic and antipyretic effect, it dilutes the blood. Also, the drug has a slight anti-inflammatory effect. Indications for use are fever and various types of pain, heart attack, stroke, ischemia, arterial diseases and heart valve pathologies.

Medications based on acetylsalicylic acid can not be used by pregnant women in the first and last trimester because of the risk of bleeding. Also, drugs are strictly prohibited for children under 15 years of age. Do not take medicine for certain diseases of the heart, blood vessels and blood. Renal and hepatic insufficiency, ulcer and erosion of the digestive tract is an excuse to refrain from using painkillers containing acetylsalicylic acid. Medicines, which contain the described substance, have the following names:

• "Aspicor".
• "Aspirin".
• CardiAsK.
• "Upsarin UPCA" and many others.

In recent years, these drugs are practically not used to treat rheumatism, arthritis, pericarditis.

Metamizole sodium, or analgin

A medicinal preparation used as an analgesic can have sodium metamizole as the main substance . This compound is a derivative of pyrazolone, it also belongs to the NSAID group. The medication is able to provide analgesic, anti-inflammatory and antipyretic effects. It is often metamizole sodium used in the composition of the lytic mixture with white fever. It is prescribed for rheumatism, arthralgia, pain of a different nature, inflammation, myocardial infarction and thrombosis. This drug, used as an analgesic, is used for tumors, injuries, insect bites, in the postoperative period.

It is counter-indicative to use medicines based on sodium metamizole while inhibiting hematopoietic function, hepatic and renal insufficiency, anemia, future mothers and lactating women. The drug is given in the form of tablets and a solution for injections. Trade names that you can meet:

• "Analgin".
• "Spasdolzin".
• The Baralgin.

During treatment with sodium metamizole, urine can be colored red.

Ibuprofen: proven active ingredient

Painkillers for children are often required for dental, headache, injuries, otitis, sprains and bruises. Medicines for children are necessary in the period after vaccinations, for the relief of signs of a viral and bacterial infection. The most popular among all formulations is a medicament based on ibuprofen. This NSAID is able to inhibit COX 1 and COX 2. The drug reduces vascular permeability, thereby relieving inflammation. Medication after ingestion works almost instantly. He removes the stiffness of movements, eliminates swelling, and heals painful sensations of a different nature. Analgesic drugs based on ibuprofen eliminate pain during teething, ease the state of children with fever.

Compositions are produced in the form of suspensions, suppositories, tablets and injections. Trade names of preparations:

• "Nurofen."
• "Advil".
• "Moment".
• "Faspik" and so on.

Take these drugs is not recommended for ulcerative lesions of the stomach, hypersensitivity, certain pathologies of blood and severe kidney failure. To children of younger age (from three months) medicines in the form of a suspension and suppositories are appointed.

Ketorolac: a strong anesthetic

It presents anti-inflammatory and analgesic preparations with Ketorol and its structural analogues. They contain active ingredient ketorolok. It has a strong analgesic effect and has a pronounced anti-inflammatory effect. Such medications are worse than the previous ones cope with high body temperature, but are still characterized as antipyretic. Painkillers based on ketorolac are prescribed for pain syndrome of different origin: trauma, dental and headache, migraine, arthrosis and arthritis, dislocations, postoperative period, oncological diseases and so on.

The active substance has the following denominations:

• Ketorol.
• "Ketanov".
• Ketorolac.
• "Ketalgin."

Compositions are issued in the form of injections, tablets, external agents and eye drops. It is inadmissible to use drugs with high sensitivity, somatic diseases, heart and liver failure, diabetes, during pregnancy and lactation. You can not combine these medications with corticosteroid drugs and anticoagulants. There is no proven safety in using antipyretics in children under 16 years of age.

Paracetamol and its derivatives: all known drugs

Antipyretics, analgesics, often prescribed for young children, represent the active substance paracetamol. It has long been used in medicine, including pediatrics, and has proven safety. In the absence of contraindications, it is permissible to use it even in newborn children. Medicines based on paracetamol:

• The "Kalpol".
• "Panadol".
• "Cefekon."
• "Efferalgan" and so on.

Medicines are available in the form of suppositories, tablets and suspensions. They perfectly cope with the pain syndrome and reduce body temperature. But the compositions have no pronounced anti-inflammatory effect. In this regard, paracetamol-based agents are used in various types of pain and fever. Do not use drugs for violations of the liver and kidneys, alcoholism. Tablets are contraindicated for children under 6 years. For babies it is worth choosing candles or syrup.

Diclofenac: an effective anti-inflammatory drug

If you need anti-inflammatory and analgesic drugs, then give preference to drugs based on diclofenac. Their trade names are:

• Orthofen.
• Diclofenacol.
• Dicloran.
• Voltaren and others.

It is unacceptable to take them only in cases of hemopoiesis, in the last trimester of pregnancy and ulcerative-inflammatory diseases of the digestive tract. In children under 6 years of age, medication is not used due to the lack of clinical studies. Drugs based on diclofenac are prescribed for pain and febrile syndrome, they effectively relieve the symptoms of colds, improve well-being. Has a strong anti-inflammatory effect. Therefore, it is recommended for diseases of the joints, neurological pathologies. Practice the application and in gynecology. The medication also has anti-rheumatic and anti-aggregation effects.

Indomethacin: a substance with less popularity

Often a person needs painkillers for toothache. These include medications based on indomethacin. This substance has a pronounced analgesic effect. It is effective in migraine, neurological and gynecological pains. Also, the medicine has a good anti-inflammatory effect. It is recommended to use the composition for diseases of joints and tissue traumas, infectious pathologies of ENT organs. Effective will be medication for the violation of the musculoskeletal system.

Contraindications to the use of medications on the basis of indomethacin can be called gastric ulcer, bleeding, certain diseases of the organs of vision, pathology of the vestibular apparatus, pregnancy and child age. Trade names of medicines that you can meet at pharmacies:

• "Indomethacin".
• "Metindol".
• "Indotard" and others.

Means are given for ingestion, rectal administration, external use and in the form of eye drops.

Naproxen: antiaggregant with anti-inflammatory effect

Painkillers for headache and other types of it represents the active substance naprexen. This medicine removes inflammation, facilitates the patient's condition. In a short time, the medicine will stop the pain syndrome caused by different causes. Apply the composition for dental, headache, myalgia, arthralgia, neuralgia, muscular discomfort, female periodic ailments. Effective naproxen in degenerative diseases of the support apparatus. Do not use the composition in renal and hepatic insufficiency, intolerance of the active substance. It is dangerous to use medicines in children of the first year of life. Adult patients usually tolerate the following drugs:

• "Nalgezin".
• "Naprisen".
• Sanaprox.
• "Naprios" and so on.

Nimesulide and preparations based on it

If you need strong painkillers, you can give preference to drugs that include nimesulide. These medicines have the following trade names:

• "Nyz".
• "Nimesil".
• "Nimika".
• "Nemux" and so on.

Medications are classified as non-narcotic analgesics. They quickly and permanently eliminate the pain syndrome of different localization. Also, the drug has a pronounced anti-inflammatory effect. Medications based on nimesulide are used to eliminate febrile syndrome, when drugs with ibuprofen and paracetamol are powerless. Clinical studies have shown that this drug is stronger in its action than its predecessors. It is important to remember that Nimesulide and its structural analogues can not be used for ulcerative lesions of the intestine and stomach, liver failure, drug addiction and alcoholism. Some deviations in the work of the cardiovascular and hematopoietic system should be the reason for replacing the drug with another compound. Indication for the use of drugs is acute pain syndrome.

OXICAMES: NSAID GROUP

Among all non-steroidal and anti-inflammatory drugs, it is possible to isolate medicines-oxicams. They have different active substances and trade names. Here are some of them:

• Lornoxicam ("Xefokam", "Zornika");
• Meloxicam ("Movix", "Lem");
• Piroxicam (Finalgel, Kalmopyrol);
• Tenoxicam ("Tenikam", "Tobitil").

Medications are prescribed for relief of pain syndromes and removal of inflammatory processes. Each drug has an antipyretic effect, the effect of which in this or that case may differ. Before using any of these medications, you should read the instructions, since all drugs have separate use restrictions and special instructions.

Features of painkillers and anti-inflammatory formulations

Virtually all painkillers are dispensed from pharmacies without medical attention. But this does not mean that they can be taken thoughtlessly and in unlimited quantities. All pain relievers have their own treatment term. To stop the pain syndrome, they are taken no longer than five consecutive days. If you need funds to reduce the temperature, then it is permissible to use them only for three days. Doctors can prescribe medicines for a longer period of time with the aim of removing inflammation. But you need to monitor the functioning of vital organs and monitor the blood. Take painkillers at a certain time. Usually a gap of at least 4 hours is established. Some remedies can not be taken again, before 6-8 hours. This information is always written with instructions, carefully read it.

Interesting information about the products presented, obtained by comparing them

You already know that all anesthetics and antipyretic drugs have an anti-inflammatory effect, more or less. The conducted researches showed which means will be stronger.

On the analgesic effect, the active substances go in descending order:

• Ketorolac;
• Diclofenac;
• Indomethacin;
• Naproxen;
• Ibuprofen.

If you judge by the strength of the anti-inflammatory effect, you can get the following classification:

• Indomethacin;
• Diclofenac;
• Naproxen;
• Ibuprofen.

Taking any of these medicines can cause bleeding in the gastrointestinal tract, vomiting, or nausea. Also, some formulations individually cause an allergic reaction. If, during treatment, you suddenly feel worse or have new symptoms of the disease, then you should not hesitate. Call your doctor as soon as possible. Especially responsibly and cautiously one should approach the use of painkillers for children. It is strictly forbidden to take similar compounds with abdominal pain of unknown origin. Medications can lubricate the clinical picture of dangerous pathological conditions. The consequences of this are very unpleasant.

Instead of concluding

From the presented article, you could learn about the drugs that are used by consumers for the purpose of anesthetizing and relieving inflammation. It is worth remembering that many medicines have exceptionally symptomatic treatment. They facilitate the patient's condition, remove discomfort and eliminate fever. But they do not act on the cause of the indisposition. If you feel unwell, it is advisable to contact the doctors for help. Only a qualified specialist will be able to establish the cause of your illness, after which he will appoint the right treatment. Be healthy and live without pain!