Analog "De-Nol", a domestic preparation. "De-Nol": domestic analogues in Russia, reviews

Unfortunately, people who suffer from ulcer diseases of the gastrointestinal tract are becoming more and more. And many of them have already experienced first-hand the effectiveness of the drug "De-Nol". But that's about what there is an analogue of the "De-Nol" domestic, which is not inferior to the pharmacological action of foreign funds and costs several times cheaper, know not all. It is with such drugs that we will get acquainted further.

The drug "De-Nol"

Before proceeding to consideration of drug substitutes, it will be correct to recall the characteristics of the "De-Nol" remedy.

So, this medication has both astringent and antiseptic effect, therefore it is effective in the treatment of peptic ulcer diseases. Produced in the Netherlands, which explains its high enough cost.

The drug is produced exclusively in a tablet form and can be administered to patients from 4 years of age. Like the "De-Nol" tool, analogues (domestic and foreign) in tablets for the treatment of young children are not used because of the impossibility of accurate dosing.

Pharmacological properties of the drug

The main component of the drug is bismuth tricalcium dicitrate. This active substance, getting into the stomach, settles in undissolved form and forms a protective film on the surface of ulcers and erosions. In addition, the drug promotes the production of prostaglandin E and activates the process of mucus formation. Patients already after 10 days of taking medication have increased epidermal growth in the areas of defects.

Drug analogues

With peptic ulcers, gastritis and other ailments of the gastrointestinal tract, which are characterized by damage to the integrity of the gastric mucosa, the doctor can prescribe to the patient an analogue of "De-Nol" - domestic or foreign. The specialist, depending on the nature of the disease and the degree of its severity, will select the most suitable and effective medicine. This can be as one of the structural substitutes, and a drug similar in pharmacological characteristics.

Like the "De-Nol" remedy itself, analogues in Russia can be purchased in virtually any pharmacy kiosk. It does not require a prescription from the attending physician. However, it should be noted that over-the-counter medication leave can not be a motivation for self-treatment. After all, such carelessness can cause a deterioration in health and contributes to the emergence of complex concomitant diseases.

The drug "Novobismol"

This antiulcer is produced in Russia and has a bactericidal effect on Helicobacter. The active substance of the drug is bismuth tricalcium dicitrate. Due to the presence of this component, the drug has both anti-inflammatory and astringent properties.

Getting into the acidic environment of the stomach, the drug binds the protein substrate, which secrete the damaged areas of the mucosa. As a result of this process, a film forms on the surface of ulcers and erosions. In addition, this analogue of "De-Nol" (a domestic drug "Novobismol") improves the secretion of bicarbonate and the synthesis of prostaglandin E.

Applied remedy for diseases such as functional dispersion, chronic gastroduodenitis and gastritis in the phase of exacerbation, duodenal ulcer and stomach. It is often enough to prescribe medication for patients with irritable bowel syndrome.

Recommended medication for patients from 4 years, but the daily dose should be calculated by a specialist individually. Take the remedy 30 minutes before meals 2-4 times a day for 6-8 weeks.

Reviews about the medicine

Well in the treatment of ulcer diseases, not only the drug "De-Nol" has proved itself. Analogues domestic, "Novobismol" in particular, are also quite effective. This is evidenced by positive feedback from patients and doctors.

As for single cases, when patients negatively speak about the drug, the reason for this is the side effects of Novobismol tablets. And this is understandable, because encephalopathy, various violations of intestinal motility, nausea, vomiting, skin rashes (this is the possible reactions of the body to the remedy), give a lot of discomfort.

In addition, this analogue of the "De-Nol" (the domestic drug "Novobismol") is contraindicated in cases of liver and kidney disorders and during the period of the baby's gestation and breastfeeding, which also causes resentment in some people.

The drug "Venter"

This drug of domestic production is an analogue of the "De-Nol" means for the pharmacological group. He is prescribed to patients suffering from gastritis and ulcerative gastrointestinal diseases. The drug may be recommended for preventive purposes to prevent the recurrence of erosive and ulcerative ailments. It is often used to treat chronic gastritis and non-ulcerous dispersion. This analogue of "De-Nol" (a domestic preparation "Venter") is effective as a part of complex therapy with hyperacid gastritis, peptic and medicinal ulcers, as well as gastroesophageal reflux disease.

As for the main active component of the drug, this function is performed by sucralfate - disaccharide. The substance consists of sucrose sulphate and aluminum hydroxide. It interacts with the protein, which is formed in the damaged areas of the mucosa, thus creating a protective film. This "shield" protects erosion and ulcers from the action of hydrochloric acid and promotes effective regeneration of tissues.

Application features and dosing system

Like any analogue of the "De-Nol", the domestic medication "Venter" must be used 30 minutes before meals. The daily dose of the drug is from 2 to 4 tablets and depends on the disease and the nature of its course. To achieve the maximum therapeutic effect and avoid possible side reactions, the calculation of dosing should be entrusted to the treating doctor. The specialist will take into account all the individual characteristics of the patient and determine the duration of the course of therapy.

Refuse the use of the drug is necessary for dysphagia, chronic renal dysfunction, bleeding or intestinal obstruction. Contraindications to taking medication are also pregnancy and lactation period.

Opinion of patients about the preparation

Like the drug "De-Nol", the analogues of domestic reviews are mostly positive. This is due to the high effectiveness of drugs, which is achieved through the pharmacological action of the main components. In particular, patients respond well about the preparation "Venter". Judging by their words, people are very happy with the results of treatment. They note the rapid improvement in the condition, the availability of the drug and other advantageous characteristics that the drug possesses.

Despite the mass of grateful reviews, there are those patients whose memories of therapy cause only negative. Some had to experience side effects of medication, such as myalgia, vertigo, bloating, skin rashes, nausea, vomiting, or headaches. Each of these manifestations causes significant discomfort.

The medicine "Ventrisol"

As a rule, people choose domestic analogues in the process of searching for a substitute for the drug "De-Nol". "Ventisol", meanwhile, is not in the least worse. This means of Polish production, and it is often prescribed to patients who have ulcerative and erosive lesions of the gastrointestinal mucosa.

This drug on the composition and pharmacological action is as close as possible to the drug "De-Nol". Its main active ingredient is also bismuth, which promotes the formation of a protective film in the damaged parts of the mucosa. The product is produced in tablet form and is indicated for use in gastritis, ulcerative lesions of the stomach and duodenum, as well as gastroduodenitis.

The active component of the drug protects erosion and ulcers of the mucous membranes from the negative effect of hydrochloric acid, which contributes to their rapid scarring and healing. In addition, bismuth does not affect the acidity of gastric juice.

With regard to the features of the application and the dosing system, then, like the means of "De-Nol", the drug "Ventrisol" must be used 30 minutes before eating. The course of treatment depends on the severity of the disease, so only the attending doctor is competent in this matter.