The preparation "Bifosin": instructions for use, composition, description, analogues and reviews

Do you know what the Bifosin medication is? Instructions for use, price, testimonials and indications for taking the mentioned preparation will be described further. Also from the article you will learn about what features are inherent in this tool, whether it has side effects, analogues and contraindications.

Form of the preparation, its composition, description and packaging

In what forms does the Bifosin medication go on sale?

• Cream. Instructions for use say that the main substance of this drug is bifonazole. As additional components, macrogol 400, propylene glycol and macrogol 4000 are added to it. A colorless 1% cream for external use has a uniform structure and is available in aluminum tubes packed in cardboard packs.
• White or light cream powder (can be with a greyish hue) for external use. Its active element is bifonazole, and auxiliary substances - corn starch, zinc oxide and talc. On sale it comes in polyethylene jars.
• Lightly colored or colorless transparent solution for external use. Its active ingredient is bifonazole. As for additional substances, they include macrogol 400. You can buy this form in bottles of dark glass (droppers).
• Spray "Bifosin". The instruction for use states that this product is marketed as 1% transparent and colorless liquid for external use. Its active substance is bifonazole, and propylene glycol, macrogol and isopropanol are used as auxiliary elements. You can buy this form in polymer bottles equipped with a sprayer.

Features of the drug

What properties are inherent in all forms of Bifosin? Instruction for use reports that it is an antifungal agent. The main target of this medication are membrane components of such fungal cells as ergosterols.

Bifonazole, which is part of this drug, is able to inhibit the synthesis of ergosterol at two stages of its formation. As a result of the functional and structural effects, the cell membranes of the fungal cell are damaged.

With respect to which bacteria is Bifosin effective? The instruction for use states that this medication can adversely affect dermatophytes (it has a fungicidal effect on the trichophyton, epidermophyton and microsporium), as well as yeast-like and mold fungi (exerts a fungistatic effect).

It should also be noted that the medication in question has no effect on enterococci.

The minimum amount of a drug that has an effective antifungal effect is 5 ng / ml.

The concentration of the drug in 20 ng / ml promotes fungicidal effect (against fungi of the genus Candida), and in lower doses - fungistatic effect.

Pharmacokinetics

Is the external preparation Bifosin absorbed? Instructions for use (the price of the drug is presented below) indicates that this medication penetrates well into the layers of the skin. Its absorption is 0.6-0.9%. In this case, the concentration of bifonazole in the blood is not determined.

After applying the cream or other forms of the drug (after 6 hours), the percentage of bifonazole in the skin is many times higher than the minimum effective concentration for harmful effects on fungi.

The duration of the active substance in the skin is 36-72 hours. Drug is withdrawn after 19-32 hours, depending on the density of the dermis.

Indications

In what cases is the external preparation "Bifosin" prescribed? Instructions for use, reviews of dermatologists report that this medication should be prescribed only by a narrow specialist.

As a rule, it is used to treat skin that has been affected by dermatophytes, molds and yeast-like fungi, this is:

• Smooth skin dermatomycosis;
• Pityrious lichen;
• Mycosis of hands and feet;
• Candidiasis of skin superficial;
• Dermatomycosis on the head (use only powder, solution or spray);
• Erythrasma.

Contraindications

Contraindications for this drug is not very much. They include:

• The period of breastfeeding;
• Hypersensitivity to drug substances.

Also it should be noted that with special care this medication is prescribed to babies up to a year and pregnant women in the first trimester.

Preparation "Bifosin": instructions for use

The drug for external use should be used once a day, before bedtime.

Cream, powder or solution is applied a thin layer on the affected area of the skin and rubbed gently. As for the spray, it is sprayed in the amount that is sufficient to thoroughly moisten the covers. Also, the drug is applied to adjacent areas. What is the dosage?

To treat a palm-sized skin area, you need to use a strip of cream 0.5-1 centimeter in length or a few drops of a drug solution (about 3 ml).

To achieve a satisfactory therapeutic effect, treatment should be continuous throughout the following periods:

• With erythrasis and deprivation of pityriastomas - 2 weeks;
• With mycoses of interdigital patches and feet - 3-4 weeks;
• With dermatomycosis smooth skin - 2-3 weeks;
• With dermatomycosis of the head - 4 weeks;
• With candidiasis of the skin (superficial) - 2-4 weeks.

After eliminating all the symptoms of mycosis, the drug continues to be used for prevention, applying it once a day for two weeks.

Adverse events

What side effects occur when using Bifosin? The instructions for use say that this remedy can cause local reactions such as skin irritation, hyperemia, burning sensation, eczema, allergic reactions, vesicular rash, itching, maceration, allergic dermatitis and peeling.

The listed phenomena are reversible and disappear immediately after the cessation of treatment.

Cases of overdose

What symptoms of overdose occur when the drug is misused? Experts say that low systemic absorption of this drug makes an overdose impossible.

Special Recommendations

If there is no therapeutic result, you need to see a doctor and undergo an additional examination. In accordance with the analysis data, the treatment is adjusted.

Avoid contact with the external preparation in the eyes and other mucous membranes.

The use of the drug in infants (up to one year) is possible only under the supervision of the pediatrician.

Cost and analogy

The price of this product depends on the form of its release and can vary within the limits of 40-120 rubles. As for the analogs, the following means are referred to them: Bifasam, Mycosorp, Bifonazol, Mifungar, Ekodaks, Dermazol, Amiklon, Travogen, etc.

Reviews

Now you know what the Bifosin medication is. Cream (instructions for use, price, reviews described in this article), as well as other forms of this drug is often prescribed for fungal skin lesions. Patients argue that this tool perfectly copes with the task. After a few days of treatment, fungal manifestations completely disappear.

Another plus of this drug is its low cost.