The drug "Riboxin": for what, to whom is shown and contraindicated

Energy metabolism is an important component of functioning of living cells, because without this substrate no chemical reaction can take place, which means that tissues will not receive nutrition, the heart stops, and the brain dies from starvation. That is why the most important source of energy in our cells, the cycle of tricarboxylic acids (otherwise the "citrate cycle" or "Krebs cycle") is activated every microsecond of the present time, and in medicine appeared the metabolic drug "Riboxin". For what purpose it is appointed and what is its mechanism of action, we will understand further.

The value of energy

And for the implementation of energy metabolism, a constant circulation of substances is necessary , because the substrate for reactions is received by the person with breathing (primarily oxygen) and nutrition (all organic and inorganic compounds). And so the changes in these important turns affect the state of our body, and vice versa. So, this happens in case of serious illnesses that lead to damage to the internal organs, primarily the heart and liver. Therefore, in addition to the therapy of the main pathology, preparations are needed to improve metabolism in cells, one of which is the Riboxin drug. What is he appointed for? To improve metabolism, because its active substance - inosine - is the precursor of ATP (adenosine triphosphate), almost the only energy molecule in our body.

Indications concerning the heart

The organs of the "first row" responsible for metabolism are the heart and liver. First, since the rate of blood circulation in our body depends on the level of his work, and as a result, oxygen saturation in the lungs, filling with nutrients in the small intestine, detoxification of toxins in the second most important organ and liver metabolism. And if the heart has undergone dystrophic changes, then improvement of its work is required due to the drug "Riboxin". What this depends on, we will understand further. First, the myocardium (the muscle of the heart) of its three layers is much more often and more easily affected by external influences, because it works tirelessly every second of our life. Therefore, his dystrophy occurs after frequent heavy physical exertion, severe infectious diseases, he undergoes heart attacks, myocarditis, changes due to lung pathology (so-called "pulmonary heart"). Therefore, the therapy of the underlying disease and the reinforcement of the effect with the drug "Riboxin" is necessary, for which it is prescribed even if the patient has congenital or acquired heart defects.

Other indications

In addition, the expressed metabolic disturbances in our body also occur with endocrine pathologies, diseases of the liver, kidneys and gastrointestinal tract. Some of them are also indications for the use of the drug "Riboxin". Why is he appointed in this case? The indications remain unchanged - the restoration of metabolism, which is disturbed by cirrhosis of the liver, its alcoholic or medicinal damage, as well as fatty dystrophy, in addition to ulcers of the stomach and duodenum, urocoppororphy, poisonings by medical means, chronic alcoholism, radiation effects and operations, Associated with the temporary isolation of the organ from the general circulation. As a rule, the drug "Riboxin" is injected intravenously, but there are other forms of it - capsules and tablets (more for outpatient use).

Pharmacological properties

The main effects of this drug are antihypoxic, antiarrhythmic and metabolic. Due to this, it significantly improves own blood circulation of the heart (in the coronary arteries), as a result of which the myocardium becomes more resistant to stress, increases its relaxation in diastole and the number of contractions. In the case of hypoxia or ATP deficiency, when the body experiences oxygen and energy starvation, Riboxin is also recommended, for what and how it works in this case, we will understand a little more. The fact is that the main source of ATP is glycolysis, the exchange of glucose in cells. And this drug directly affects it, activating and accelerating its enzymes, the metabolism of pyruvate, the start of xanthine dehydrogenase, the synthesis of nucleotides. In addition, it "liquefies blood" by reducing aggregation of platelets, and also improves tissue regeneration, especially the myocardium and mucous membranes of the digestive system.

Special cases

In addition to therapists, obstetrician-gynecologists also often recommend to their patients the drug "Riboxin" during pregnancy. For what and what is the effect of this, let's work it out together. Firstly, it must be remembered that when the fetus develops, its tissues are provided with oxygen and nutrients exclusively from the mother's body. Therefore, if the mother has anemia or diseases of internal organs, her own metabolism can not cope with the needs of both of hers and growing inside the baby. And then you should resort to the drug "Riboxin" during pregnancy, for which it is recommended by doctors. Since in the first place it is necessary to provide comfort for the proper laying of organs and the development of the child, it will depend on how it will be born and grow. That's why if an obstetrician-gynecologist allows you to take this medication and sees you have indications for using it, then do not be afraid, because the baby's health is in your hands, especially when he is still developing inside you, dear future moms.

Contraindications

In general, the drug is fairly safe, but it is necessary to stop taking it if the patient has hypersensitivity to its components, kidney failure and gout. This is so because allergic reactions (hyperemia and / or itching of the skin), hyperuricemia (an increase in the amount of uric acid in the blood), which leads to exacerbations of gout and damage to the kidneys, are side effects even when taking a therapeutic dose (and even more so). In other cases, the drug is safe and actively recommended by doctors.