The drug "Metronidazole": indications for use

"Metronidazole", the indications for the use of which are mandatory, are antimicrobial and antiprotozoal.

Produced in various dosage forms:
- Powder for the preparation of intravenous solution, solution for infusion;
- suspension for ingestion;
- and a variety of tablets, vaginal, coated.

Pharmachologic effect:

The drug "Metronidazole", the indications for the use of which are very diverse, can be used to treat protozoal infections, extraintestinal amoebiasis, trichomoniasis, amoebic dysentery, cutaneous leishmaniasis, giardiasis, etc.

They can be treated with various infections: CNS (meningitis, pneumonia, bacterial endocarditis, brain abscess, sepsis), bone joint infection, abdominal infection (liver abscess, peritonitis), pelvic organs (ovary and fallopian tube abscess, endometritis, vaginal vault). "Metronidazole" is used in the treatment of pseudomembranous colitis, duodenal ulcers or gastritis. It is also used in the prevention of postoperative anaerobic infection, with chronic alcoholism, in radiation therapy in the treatment of cancer patients; Also for the treatment of vulgar and rosacea, trophic ulcers, long-term non-healing wounds and bacterial vaginosis with external and local application.

"Metronidazole", the indication for which is strictly limited, can not be taken by pregnant women (especially in the first trimester), breast-feeding, patients with hypersensitivity to the components of the drug, with organic lesions of the central nervous system (epilepsy), and liver failure. Women who are after the second trimester of pregnancy, as well as patients suffering from kidney failure, in order to avoid complications, should take this medicine cautiously. Children drug is contraindicated, except for cases of amoebiasis.
If the patient has been taking the drug "Metronidazole" for a long time , nikomed, the instructions for use indicate the occurrence of side effects.
Digestive system: nausea, decreased appetite, intestinal colic, vomiting, diarrhea, metal taste or dry mouth, pancreatitis, stomatitis.
Nervous system: there is a disturbance in coordination of movements and dizziness, depression or increased irritability, irritability, confusion, insomnia, headache, weakness, convulsions or hallucinations.
Allergic reactions: arthralgia, urticaria, nasal congestion, skin rash, fever.
Urinary system: cystitis, polyuria, dysuria, candidiasis, staining urine in an unaccustomed dark brown color, incontinence,

How to take metronidazole?
It is necessary to adhere to the dosage and methods of using this medication. The drug is administered orally during or after a meal, you can drink it with milk, do not chew. Depending on the disease, age, its different dosage is distinguished.

Amoebiasis: adults take the medicine three times a day for 0.6-0.8 g, for 8-10 days. The dose for children is prescribed at the rate of 1 kg of weight 35 - 50 mg, 3 times per day, for the same period.
Giardiasis: 1 kg of weight, 15 mg, 3 times a day, treatment time - 5 days.

Trichomoniasis: for adults it is prescribed inside, twice a day for 400 mg, for a week. After a week, if necessary, a second course of treatment is prescribed. Treatment of partners is simultaneous. For children under 5 years, the estimated dose is up to 0.25 g per day, in 5-10 years the usual daily rate is 0.25-0.375 g, at the age of over 10 years, children are prescribed 0.5 g each, and the daily portion is divided into three times.

In severe cases, the drug "Metronidazole" is administered intravenously with the help of droppers. Adults drip 500 mg of the substance in 100 ml of solution, children - per kilogram of weight on average 7-8 mg, in the same amount of solvent.

Chronic alcoholics injected daily for 0.5 g, for six months.

Intravaginal: for 10 days, at night for 500 mg. External: the dose is set by the doctor individually, apply to the day 2 times.

The drug "Metronidazole", indications for use and dosage which is determined by the doctor individually, can cause an overdose. As a result of taking an increased dose, there are ataxia, nausea, vomiting. In severe cases, there may be epileptic seizures, peripheral neuropathy. A special antidote for the poisoning of this drug has not yet been found. It is necessary to carry out symptomatic treatment.

Special instructions:
It is strictly forbidden to apply "Ethanol" during treatment. With prolonged therapy, it is necessary to constantly monitor the blood on the control. With leukopenia, further treatment is associated with the development of the infectious process. When there is ataxia, dizziness and any other deterioration in the health of patients, treatment stops. When treating trichomonadal vaginitis in women and trichomonas urethritis in men, it is necessary to strictly abstain from sexual activity, and treatment of sexual partners simultaneously.

The drug is incompatible with alcohol.

Pharmacokinetics:
Basically, after intake is absorbed by the body completely. The intake of food for absorption is not affected. Quickly distributed in the body.

Conditions and periods of storage: It is stored no more than 3 years in a dark place, the storage temperature is up to 25 ° C. Not available for children!
It is released in pharmacies only on prescription.