The drug 'Diovan'. Instructions for use and brief description

"Diovan" is a specific active antagonist of angiotensin II receptors. It is intended for oral administration. Due to the fact that the instruction is attached to the "Diovan" preparation, the consumer can learn about the mode of its operation. This drug blocks the AT1 receptors responsible for angiotensin II. As a result, the plasma concentration of angiotensin II, which stimulates the unblocked receptors of the AT2 subtype, is increased.

There are several indications for the use of the drug "Diovan". The instruction manual allows you to familiarize yourself with them. It:

- heart failure (chronic);

- arterial hypertension.

Diovan tablets are prescribed in order to increase the likelihood of survival in patients with acute myocardial infarction, which is complicated by left ventricular systolic dysfunction or left ventricular failure, with the stability of the indices of geodynamics.

The effect of this drug in heart failure is based on its ability to eliminate

- cell proliferation, which leads to remodeling of the heart, blood vessels, kidneys;

- fluid retention in the body;

- vasoconstriction;

- stimulation of excessive synthesis of hormones such as aldosterone, endothelin, vasopressin, catecholamine, etc.

In the treatment of arterial hypertension, the action of the drug "Diovan" is observed after two hours. The limiting pressure decrease is observed after about 5 hours. The action of the tablets lasts more than 24 hours. With the repeated use of "Diovan", the pressure decreases as much as possible already in the second-third week and is maintained for a long time at the achieved level. It should be noted that, in accordance with the data provided by the instruction attached to the "Diovan" preparation, a sharp cessation of the use of the drug does not lead to a sudden increase in pressure or to any other adverse clinical effects.

In cases where Diovan tablets are used after myocardial infarction, the active ingredient of the drug, valsartan, reduces the risk of death by 25%.

Before using this medication, you should carefully read the contraindications for taking the drug "Diovan". Instructions to the medicine contain their list:

- Pregnancy;

- lactation;

- special sensitivity to any component present in the formulation.

Also with extreme caution should take tablets "Diovan":

• While observing a diet with limited sodium content;

• Patients who have bilateral stenosis of the renal arteries ;

• With hepatic insufficiency, which arose against the background of bile duct obstruction;

• Patients with renal insufficiency;

• During diarrhea, vomiting.

After reading about the drug "Diovan" reviews, you can find out about such frequent side effects as:

- viral infections,

- neutropenia,

- postural vertigo,

- Orthostatic hypotension.

In some, more rare cases, upper respiratory tract infections, hyperkalemia, sinusitis, insomnia, fainting, pharyngitis, decreased libido, heart failure, hypotension, cough, as well as abdominal pain, diarrhea, vertigo, back pain, asthenia, fatigue , Swelling. Very rarely, but rhinitis, thrombocytopenia, itching, rash, headache, nausea, vasculitis, angioedema, arthralgia, renal dysfunction, myalgia may occur.

The signs of an overdose with this drug are also described in the annotation. In order to avoid this, before using Diovan, instructions for its use should be carefully studied by the consumer. It describes the method of taking the drug and the dose, and describes all the symptoms of overdose and measures for first aid.