Sodium oxybutyrate - instructions for use, description, analogues and reviews

Sodium oxybutyrate is a solution for intravenous anesthesia. Until recently, this white crystalline powder, soluble in water and ethyl alcohol, was the most common means for anesthesia in light surgical interventions. In a word, the drug had an anesthetic, sedative, relaxing and hypnotic effect.

Once sodium oxybutyrate (Natrii oxybutyras), the instruction of which is considered for the indication of indications for use, dosages and precautions, could be found in any surgical block or ambulance. But today the drug with this name does not exist, it was withdrawn from sale, so in no pharmacy it can not be purchased. Absolute analogue is sodium oxybate, but there are other means with a similar composition and indications for use.

Surgical operations

In a simplified language, the drug was included in the category of funds for "easy anesthesia", that is, it was well used for surgical operations:

• Children;
• Depleted patients;
• Elderly people with low blood pressure;
• The elderly are in a state of shock;
• People with kidney or liver failure.

Sometimes such anesthesia was used to conduct diagnostic procedures, if there was no certainty that the patient would psychologically tolerate them.

Description of the substance sodium oxybutyrate primarily indicates that the drug is intended for injection into anesthesia in operations with a low degree of trauma, that is, not with cavitary operations.

Post-operative appointment

Sometimes it could be used after the surgery, if the patient developed postoperative psychosis.

This is a fairly common phenomenon, especially in elderly patients. The person demonstrates all the signs of psychosis: hallucinations, motor agitation, confusion, memory and speech impairment, only the cause of these symptoms is surgical anesthesia, against which there was a disruption of blood circulation or metabolic processes in the body, a sharp decrease in blood pressure, anemia, The side of medical personnel.

In this case, sodium oxybutyrate was used with a high degree of efficiency. The instructions for use contained information that it was necessary to dilute the drug in a glucose solution and a slow intravenous injection. In the overwhelming majority of cases, the patient returned to normal and safely left the anesthesia.

Today, after the drug was withdrawn from production and sale, other agents are used as analogues in these situations, for example, "Sombrevin" or thiopental sodium.

Use in Obstetrics

At the time of delivery, sodium oxybutyrate was often used. Instructions for use recommended to use it as a so-called therapeutic anesthesia. The injected drug allowed the woman in labor to rest during intensive labor, while positively influencing the resistance to lack of oxygen of both mother and fetus. Today the drug that does not exist on the drugstore shelves can be replaced with Ketamine.

Sedation effect

Often sodium oxybutyrate was used to treat mentally ill people with acute stage of the disorder. Due to the fact that the drug was sedative, anticonvulsant, normalized sleep. If the dose is low, the effect of general anesthesia did not arise, but the patient could plunge into a deep and restful sleep that would restore his strength and psycho-emotional balance.

For healthy people, the drug could be used for the purpose of anti-shock effects in stressful situations. By reducing the severity of neurological sensations and vegetative reactions, a person retained the ability to self-control, defended himself against the late effects of acute shock.

Given the fact that the drug is no longer produced, it is possible to distinguish its analogue in composition and action - "Droperidol".

Of course, this drug was used only in a hospital. After using it, a person could not maintain the usual level of vitality: he felt lethargic, drowsy while taking the drug, the main active ingredient of which was sodium oxybutyrate. The instruction, the indications in which were painted in great detail (basically everything reduces to an oppressive effect on the central nervous system), prohibits after driving a vehicle or perform any physical or mental work that requires concentration.

Improvement of cognitive functions

Sodium oxybutyrate is a good nootropic. It normalizes cognitive functions, improves memory, the process of perception and processing of information, helps to reduce tissue hypoxia (lack of oxygen). If necessary, the remedy improves the activity of all body systems, increases resistance to negative external factors of the heart, brain, kidneys.

Application in ophthalmology

At the time of the drug, there was another reason for using this particular drug (sodium oxybutyrate). The instructions for use suggested using the medicine in the diagnosis of open-angle primary glaucoma. The composition of the agent is a catalyst for oxidative processes in the retina of the eye, as a result of which a person began to see better.

Contraindications

Below, you are presented with a list of diseases and conditions in which the drug should be abandoned:

• Myasthenia gravis is an autoimmune disease in which pathological muscle fatigue is detected;
• Hypokalemia - a condition in which the level of potassium in blood serum stays at a level below the permissible norm;
• When using the drug as obstetric anesthesia, it is not possible to administer the drug to pregnant women with hypertension and severe toxicosis;
• Convulsions.

In the case of severe intolerance to the drug or an overdose, the main symptom is a violation of human breathing. A person needs urgent hospitalization, artificial ventilation of the lungs, support of the cardiovascular system. Intravenous administration of potassium chloride is indicated.

Side effects

If there are contraindications and the correct use of the drug, there could be no side effects.

Complications could occur if the drug was injected into the vein too quickly. In this case, the following symptoms could occur:

• Violation of breathing:
• Severe drowsiness,
• nausea and vomiting;
• Decrease in the level of potassium in the blood;
• Excitation and tremor.

That is why it was prescribed to carefully and technically correctly administer sodium oxybutyrate. Instructions for use allowed the simultaneous use with the drug virtually any other drugs, except for analgesics and anesthesia - the latter enhance the effect of sodium oxybutyrate. It was also not recommended to use analeptic drugs together with the drug and was strictly forbidden to drink alcoholic beverages.

Reviews

In principle, we have stated almost everything that can tell about the preparation "Sodium oxybutyrate" at the moment. The reviews left on thematic forums, in most cases, do not tell us about the direct indications of the drug (anesthesia), but about the properties of the drug.

The sedative properties of the preparation are highly appreciated. According to experts and patients, he is able to quickly calm down the nervous system, both in shock and when it is really necessary, and for any problems, anxiety, irritability. Doctors say that the drug perfectly copes with its task, and after its reception, a person feels calm and relaxed, well falls asleep and subsequently feels great. Some patients compare the injection of the drug with a portion of strong alcohol.

But at the same time, it should be noted that this is not the safest way to solve problems, since after taking sodium oxybutyrate, a dependence can develop that does not concede anything alcoholic. And, in the end, this can seriously affect the quality of human life.

In ophthalmology, the drug also enjoyed a well-deserved success. With proper application under the supervision of the attending physician, the patient's vision really improved.

Thus, the injection solution, previously called "Sodium oxybutyrate", the instruction of which suggested using anesthetic liquid, was well-deserved popularity and a high degree of efficiency. Today, the modern pharmaceutical industry offers a large number of new drugs with a similar effect, but so far medicines with the same name are used in medicine.