"Reparil-gel": description of the drug, instructions and references

About 80% of women and 30% of men suffer from varicose veins in its various manifestations. This pathology is not fatal, but requires qualitative therapy. One of the most popular drugs for her treatment is "Reparil-gel." From our article you will find out at what other diseases doctors prescribe this remedy, how to use it correctly.

Description of the medicament: composition and form of release

"Reparil-gel" is a medicinal product that is produced in Germany. It has anti-inflammatory and angioprotective effect. Pharmacological company produces the drug in three different forms:

• Powder for injection (ampoules of 5 mg);
• Dragees;
• spray;
• Gel for external use (trade name "Reparil-gel N").

The main active ingredient of the medicine is escin. This vegetable glycoside, which is derived from the fruits of chestnut horse. Eszin has a strong protective effect on the vessels. In this case, the substance is characterized by a pronounced antiexudative effect, due to which the permeability of the capillary walls decreases.

Pharmacokinetic properties

According to the instructions, the drug is quickly absorbed, and then evenly distributed over the surface of the vascular bed. The greatest concentration of active substance in the body is observed after 2 hours after application. The period of decay and excretion is up to 80 hours. The medicine leaves the body with urine.

Indications for use

At what disorders and disorders is it advisable to use "Reparil-gel"?

• Varicose disease (pathological changes in the venous wall).
• Thrombophlebitis caused by inflammatory processes on the inner shell of blood vessels.
• Phlebitis of superficial veins.
• Pain and heaviness in the legs, severe swelling.
• Violation of the brain due to injuries and concussions.
• Encephalitis.
• Bumps, abrasions, stretching.

It should be noted that before using the drug, you need to consult a doctor. The doctor will prescribe a scheme of reception, tell about possible side effects.

Mechanism of action of the drug

The main component of the drug - escin - has a venotonic effect, stimulating the activity of the adrenal cortex. As a result, the release of hormones of adrenaline and noradrenaline, which play the role of peculiar neurotransmitters, increases. They consistently bind to alpha-adrenoceptors and help narrow the lumen of blood vessels. Horse chestnut extract is also known for the ability to eliminate venous stasis observed in varicose veins.

"Reparil-gel" suppresses the synthesis of the enzyme hyaluronidase, which is responsible for the destruction of hyaluronic acid molecules. The latter controls the preservation of the natural elasticity of the walls of the veins, the content of the optimal level of fluid in the tissues of the vessels.

In general, the drug significantly improves blood flow in the limbs. It also reduces the risk of formation of thrombi and is also characterized by the presence of antioxidant properties.

Instructions for use

Dosage and the method of application of the drug is determined by the doctor, taking into account the patient's condition and the severity of his illness.

Adults with complicated thrombophlebitis and brain disorders are prescribed medication only intravenously with 2 ampoules a day. To treat encephalitis or hemorrhage, the dosage can be increased, but the daily amount of the drug should not exceed 20 mg.

Kids from one to three years are recommended to use the medicine in the form of a spray. It is administered intravenously at a rate of 0.1 mg per kilogram of the child's body weight. In the treatment of adolescent patients, dosage should be increased to 0.2 mg per kilogram of body weight.

Varicose disease is also one of the indications for the appointment of the drug "Reparil-gel." The use of medication is permissible only on the advice of a doctor. If varicose veins are accompanied by phlebitis or irregularities in the functioning of the valve apparatus, it is better to use a dragee or gel. Injections in this case are ineffective.

The course of treatment starts with taking one tablet after meals three times a day. As the patient's condition improves, dosage can be reduced to two pills a day. Gel instruction recommends applying to pre-cleaned skin areas with a thin layer. The procedure can be repeated several times a day. Strongly rub the product into the skin is highly undesirable.

Contraindications

The use of medication is not recommended for people with impaired renal / hepatic function, and also for women in the state of Rhesus-conflict.

The composition of the "Reparil-gel" is described a little higher. This information is always described in detail in the manual, it is not accidental. The thing is that patients with intolerance to active components of the drug should better not use it. Otherwise, the risk of developing allergies is increased. If the patient manifested a similar reaction, it is necessary to note the treatment and consult a doctor. It will certainly pick up an analogue tool with a similar mechanism of action.

Overdose, possible side effects

Numerous clinical trials prove that the use of the drug at recommended doses does not cause side effects. Therefore, it is so important to follow the instructions clearly. When taking dragees with a dose of more than 20 mg per day, symptoms of an overdose are not ruled out. If heat or nausea occurs, stop treatment immediately and consult a doctor.

As for the side effects, they are very rare. The most common among them are severe fever, rashes on the skin, nausea. Cases of anaphylactic shock were not recorded.

Additional recommendations

Instruction for use reports that the drug in any of its forms increases the effect of anticoagulants. Negative interaction with alcoholic beverages was not found. However, doctors do not recommend taking the drug with alcohol.

During pregnancy and lactation, medication is allowed, but only after consultation with the attending physician. Ointment "Reparil-gel" is not recommended to apply to the area of the mammary glands, especially when breast-feeding.

How much will treatment cost

The drug can be purchased at any pharmacy. A doctor's recipe is usually not required. Its cost will depend not only on the regional margins of pharmacological networks, but also on the form of implementation. For example, the powder for injection costs about 55 rubles for one ampoule, the gel for external use - from 150 rubles. The most expensive is the tablet form of the drug. For one package (100 pills) you will have to give a little more than 4 thousand rubles.

What patients say about the drug "Reparil-gel"

Reviews about this medication are very diverse, but in most cases they differ in positive color. Many patients use it to treat varicose courses. They note that a positive effect manifests itself in a few days after the start of therapy.

Another important advantage is the composition of the preparation. Presence of exclusively vegetative components allows to minimize the risk of occurrence of by-effects.

As already noted above, the drug goes on sale in several forms. Most patients prefer gel and explain their choice by the rapid absorption of the composition. After its application, no film remains on the skin. Many simply forget to drink tablets, and injections are not popular with everyone.