Pentaxim vaccine: the pros and cons of a multicomponent vaccine

Vaccination of children allowed to reduce child mortality in dozens of times. In 2011, the National Vaccination Calendar was amended. In the list of infections against which children should be vaccinated, a hemophilic infection of type b was added. In most European countries (97 countries) of this infection, children are vaccinated with the Pentaxim vaccine. In Western European countries, Pentaxim is registered as a Pentavac, but this does not change its essence.

Vaccine Pentaxim combined and provides immunity from five infections: diphtheria, whooping cough, tetanus, and polio and infections that are provoked by Haemophilus Influenzae type b (meningitis, epiglottitis, pneumonia, septicemia, etc.) Pentaxim vaccine of French origin. Its main advantage lies in the multicomponent. This reduces the number of injections. When the child is separately vaccinated against the above-mentioned infections, 12 injections are required, while the vaccination with Pentaxim requires only four injections.

In the composition of Pentaxim, the pertussis component is acellular, which significantly reduces the risk of developing unwanted adverse reactions in the child. Clinical studies in various countries have shown that all protected children with Pentaxim have a protective level of antibodies against Hib infections, three types of poliovirus, as well as diphtheria, tetanus and pertussis.

Many parents are afraid of vaccinating children due to some circumstances. What groups of children are suitable for the Pentaxim vaccine? Instruction for use says that you can vaccinate healthy children from three months. Pentaxim vaccine is recommended for children who have an unusual reaction to the first DTP vaccine; Children with medical laboratories for DTP; Children with immunodeficiency, HIV infections, chronic non-progressive diseases of the nervous system, allergic diseases, stable neurologic symptoms, febrile convulsions in the anamnesis, etc. Many parents do not get vaccinations because of frequent illnesses of children, babies with perinatal encephalopathy, atopic dermatitis, anemia, Dysbiosis and other unreasonable medical consultants from vaccinations. In this case, Pentaxim vaccine is also recommended for use. Studies by Russian scientists confirmed the safety of Pentaxim for vaccination and revaccination from all five infections of children with different health status.

Many parents are concerned about the consequences of vaccination. Pentaxim in most cases is tolerated by the child absolutely normal. A small number of vaccinated children have adverse reactions that require immediate medical attention. In general, good vaccine tolerance is achieved through the acellular pertussis component. In addition, intramuscular injection of poliomyelitis vaccine in Pentaxim reduces the risk of developing vaccine-associated poliomyelitis to a minimum.

Pentaxim vaccine does not have a clear age limit for vaccination; It includes an acellular pertussis component that can also be used to vaccinate adults. The recommendations of Russian immunology doctors regarding DPT vaccination are that vaccination of children aged 6-7 years should be carried out with vaccines containing a reduced number of antigens (ADSM or ADS). Therefore, Pentaxim is most often used to vaccinate children under 6 years of age. In addition, it can be pricked without a HIB component (which goes in a separate vial).

After the vaccination of children with Pentaxim, a temperature increase may occur. In some cases, the site of injection (injection) may be sore. Doctors do not recommend a daily course of antipyretic drugs without raising the temperature, as this can reduce the body's immune response to vaccination.

Pentaxim can be simultaneously administered with vaccines against measles, rubella, mumps, and hepatitis B.

But despite the good indicators in the clinical trials of the Pentaxim vaccine, there are a number of contraindications. Therefore, before vaccination it is necessary to consult a pediatrician.