Medication "Korglikon": instructions for use, price, analogs and indications

Various violations in the work of the heart - the problem of many people. And quite often, in order to eliminate symptoms or suspend the development of the disease, patients are prescribed drugs known as "cardiac glycosides". To this group of medicines belongs and "Korglikon". Instructions for use, indications for treatment, side effects, analogs and reviews are the main issues that patients are interested in. So what is this medicine and what properties does it have?

Composition and form of release

The preparation "Korglikon" is issued in the form of a transparent solution for injections with a slight yellowish tinge. The medicine is sold in glass ampoules of 1 ml. One package contains 10 ampoules.

The main active substance of the drug is korglikon - a biologically active glycoside, which is obtained from the leaves of the May lily of the valley. One milliliter of the solution contains 600 μg of this component, respectively, the concentration is 0.06%. As auxiliary substances in the composition there are chlorobutanol hydrate and purified water for injections.

Description of pharmacological properties of the drug

The active components of the preparation are obtained by purifying the extracts of the May lily of the valley and its varieties. This cardiac glycoside, which has a positive inotropic effect on the human body.

This drug activates the sodium-calcium metabolism of the cardiomyocyte membrane, which in turn increases the strength of the contractions of the heart muscle. Against the background of therapy, there is an increase in the shock volume of blood, a decrease in the end systolic and diastolic volume of the heart, and a reduction in myocardial oxygen demand.

Also, the drug provides a negative chronotropic effect. Treatment leads to an increase in the sensitivity of cardiopulmonary baroreceptors, reducing the excessive activity of the sympathetic system. On the other hand, the drug increases the activity of the vagus nerve, it can speed the pulse through the atrioventricular node and, thus, has an antiarrhythmic effect.

In the presence of ciliary tachyarrhythmia, this medicine slows the rate of contraction of the ventricles of the heart, lengthens the period of diastole, improves intracardiac hemodynamics. With intravenous administration, the medicine begins to act after 3-5 minutes. The maximum effect is observed after 25-30 minutes after taking the medicine.

What are the indications for treatment?

This drug is often used in modern medicine. But many patients are interested in the question of in which cases it is advisable to take medication "Korglikon". Indications for use here are different. In particular, it is prescribed to patients suffering from a tahisystolic form of atrial fibrillation. Also, the drug helps with atrial flutter of a paroxysmal type.

There are other situations in which it is advisable to use the medication "Korglikon." Indications for admission are also attacks of paroxysmal supraventricular tachycardia. In modern medical practice this drug is often prescribed for patients with chronic insufficiency of the second, third and fourth functional class. Naturally, with such a disease, injections are only part of complex therapy.

Medication "Korglikon": instructions for use

Prescribe a similar medicine can only a doctor after a thorough diagnosis. The specialist will also determine the most effective dose and schedule the injection. To prepare the solution, the contents of one ampoule are diluted in 10-20 ml of dextrose or glucose solution with a concentration of 20 or 40%.

A single dose for adult patients is 0.5-1 ml of the drug. Children aged 6 to 12 years, as a rule, receive no more than 0.5-0.75 ml of this drug. A child from 2 to 5 years of age is prescribed 0.2-0.5 ml. Introduce the solution diluted with dextrose intravenously for 5-6 minutes. The procedure is repeated twice a day with a break of at least 8-10 hours. The maximum daily dose for adults is 2 ml of "Korglikona". The duration of therapy is determined individually.

Are there any contraindications to admission?

Are all categories of patients allowed treatment with the drug "Korglikon"? The instructions for use contain information that contraindications to therapy are still available, so it will be useful to get acquainted with their list:

• This drug is not prescribed for hypersensitivity to any of the constituent components, as well as allergies to cardiac glycosides.
• Contraindications include atrioventricular blockade of the second degree, as well as intermittent complete blockade.
• The drug does not accept patients with Wolff-Parkinson-White syndrome.
• Contraindication is glycosidic intoxication.
• The drug is not used to treat pregnant women and nursing mothers.

There are also so-called relative contraindications, in the presence of which therapy is possible only under constant control. Such conditions include atrioventricular blockade of the first degree, acute myocardial infarction, hypertrophic subaortic stenosis, heart failure with diastolic dysfunction, extrasystole, isolated mitral stenosis, electrolyte level disorders, hypothyroidism, myocarditis, obesity, renal and hepatic insufficiency, alkalosis. With caution, the drug is prescribed for elderly patients.

Is the occurrence of adverse reactions possible?

Many patients before the start of therapy ask questions about possible complications when using the medication "Korglikon." The instructions for use contain information that the drug can actually cause side effects. Here is a list of the most common ones:

• On the background of treatment, some patients may develop an arrhythmia.
• From the side of the nervous system, reactions such as confusion, headaches, increased sleepiness, sleep disturbance, dizziness are possible. Reduced visual acuity is much less common. Very rarely, patients develop delirious psychosis.
• Sometimes there is a disturbance in the normal functioning of the hematopoiesis, which is manifested by thrombocytopenia, frequent nasal bleeding, thrombocytopenic purpura.
• From the side of the digestive system, such disorders as nausea, vomiting, loss of appetite, anorexia may appear.
• Local allergic reactions are also possible, which are manifested by swelling, redness of the skin, the appearance of rash and itching.

In the presence of any worsening, it is worth consulting with a doctor. Perhaps you just need to adjust the dose. But sometimes a complete withdrawal of the drug is required.

Medication "Korglikon": analogues and substitutes

For some patients, for some reason or another, the medication prescribed by the doctor may not be appropriate. What to do in such cases? Is there any way to replace the medicine "Korglikon"? Analogues of this tool in the modern pharmaceutical market are not so easy to find, since there are simply no preparations with the same active components. Nevertheless, you can try to replace it with drugs with another compound.

For example, about the same properties have the drug "digoxin". In some cases, as a substitute, you can use the drug "Strofantin", which stands out among others really fast impact. Other analogs include Digitoxin. It is worth noting that all these glycosides are derived from plant material.

How much does the drug cost?

In addition to other factors, for many patients the cost of a drug prescribed by doctors is also important. Of course, the exact amount is difficult to determine, because everything depends on the manufacturer, the financial policy of the pharmacy, the city of residence, etc.

So how much will the drug "Korglikon" cost? The packaging price of ten ampoules is about 50-65 rubles. By the way, the drug is sold by prescription. Only the doctor can prescribe to the patient the medicine "Korglikon" (the recipe in the Latin language looks like this - Corglyconi 0,06%).

Reviews of doctors and patients

In modern medical practice, cardiac glycosides are used quite often. And one of the most popular drugs of this group is exactly "Korglikon". The doctors' testimonies testify that the medicine really copes with its tasks, normalizing the work of the myocardium, eliminating the symptoms of this or that pathology and preventing the development of complications.

Patients also leave positive feedback about the drug "Korglikon." The instruction here is extremely simple, the course of treatment does not last long, and the therapy is well tolerated. Despite the possibility of developing some or other adverse reactions, statistical studies indicate that they are extremely rare. And of course, the relatively low cost is one of the advantages of this medication. The disadvantages can be attributed to the fact that not every pharmacy sells this drug, so sometimes it is quite difficult to find.

It is worth noting that in no case should you use this medication alone, as an incorrect dosage can lead to serious intoxication of the body.