Cheap and effective analog of "Tranexam"

Ordinary people and patients with hematological and other blood diseases are often at risk of developing severe or life-threatening bleeding due to low platelet count. This can be not only because of the underlying blood disease, but also from the toxic effect in the bone marrow after treatment. Such patients are prescribed with a preventive purpose of transfusion of blood and blood substitutes to prevent bleeding.

These transfusions are not without complications, ranging from mild reaction in the form of fever and more serious or even life-threatening consequences, such as infections transmitted to the patient from transfused platelets, despite carrying out various tests for compatibility. For the treatment of bleeding, Tranexam or Tranexamic acid or the analog of Tranexam, Aminocaproic Acid, is now widely used.

Application of antifibrinolytic agents

Obviously, methods to prevent bleeding in patients, as well as minimize the impact of transfused platelets will be welcomed. One possible way to achieve these goals is the use of antifibrinolytic agents, known as lysine analogues: Tranexam and Aminocaproic acid. These drugs help stabilize the clots that form after bleeding, which significantly reduces the likelihood of further bleeding, as well as the need for transfusion of platelets.

But there may be risks associated with the use of these drugs, the most important of which is the increased risk of unwanted blood clots and the occurrence of diseases (such as deep vein thrombosis) that can be potentially life threatening. The use of antifibrinolytic agents such as Tranexam, analogues of which "Aminocaproic acid", "Dicinon", "Etamsilate", "Vikasol" can reduce bleeding, as well as prevent transfusion of platelet mass.

Need to use

Patients with hematologic disorders and bleeding are characterized by the development of thrombocytopenia and severe or life threatening conditions. And this despite the use of blood transfusions to prevent bleeding, when the number of platelets falls below a certain threshold. But this can be life-threatening because of multiple complications. A possible addition to preventive transfusions is the use of antifibrinolytic drugs, specifically lysine analogs: Tranexam and Aminocaproic Acid.

"Traneksam". Instructions for use

Analogs of this acid are anthropogenic forms of the amino acid of a protein called lysine. These drugs prevent the destruction of blood clots in the body by blocking enzymes. Although the drug "Traneksam", its analogs and substitutes are used to treat severe menstrual bleeding, but they do not eliminate premenstrual syndrome, but are used to prevent bleeding in people with hemophilia who need to remove the tooth. This medication is usually given not only to the dental procedure, but also daily up to 8 days after this. Before using this medication, the doctor should be warned about the presence of kidney disease, leukemia, endometriosis or if menstrual cycles are less than 21 days or longer than 35 days.

You should not start taking monthly "Tranexam", analogues. The testimonies of patients who independently prescribe these drugs, say that the bleeding did not become less. Do not use it for more than 5 consecutive days during periods. If the symptoms do not improve after two treatment cycles, treatment correction or an additional examination is required. Do not take more than 6 tablets per day.

Hormonal contraception (eg, birth control pills, injections, implants and vaginal rings) may increase the risk of stroke, thrombosis or heart attack if used at the same time as the Tranexam analogue. Do not share the drug with another person, even if it has the same symptoms as you. It is also undesirable to use any analogue of "Tranexam" in tablets, if there is an allergy to the components of the drugs and with a tendency to thrombosis, stroke and heart attacks.

Why these drugs are prescribed

"Tranexamic acid" and analog "Tranexam" - "Aminocaproic acid" is prescribed to stop bleeding, which occurs when thrombi can not form or quickly break down. This type of bleeding may occur:

• During or after surgery on the heart or liver;
• In people who have certain bleeding disorders;
• With cancer of the prostate, lungs, stomach and cervix;
• In pregnant women suffering from premature detachment of the normally located placenta.

Tranexam, its analogues are also used to stop bleeding in the urinary tract, which can occur after operations on the prostate or kidney, or in people who have certain types of cancer. These drugs should not be used to treat bleeding in the syndrome of disseminated intravascular coagulation. What can be replaced with "Traneksam"? Analogues are cheaper and more affordable - they are "Aminocaproic acid", "Dicinon", "Etamsilat". It is "Aminocaproic acid" that is found in the class of drugs called hemostatics, and acts in the same way as "Tranexam", that is, it works by slowing the cleavage of the thrombus.

How this medication should be used

"Aminocaproic acid" is manufactured in the form of tablets and solutions (liquid) for oral administration. Usually take initially 5 g at the same time, and then once per hour for 1 g for 8 hours or until the bleeding does not stop. When "Aminocaproic acid" is used to treat ongoing bleeding, it is usually taken every 3-6 hours. Do not take the drug more or less or take it more often than prescribed by your doctor.

It is necessary to shake the bottle before each use to mix the drug well. The doctor can prescribe high doses of aminocaproic acid - up to 24 g per day and gradually reduce the dose until the bleeding stops completely.
"Tranexam", the analogue of his "Aminocaproic acid" is also sometimes used to treat hemorrhage in the eye, which was caused by trauma. This medication may be prescribed for other purposes.

Precautionary measures

With some conditions and illnesses, taking medications is contraindicated. This is in cases where there is:

• Allergy to "Aminocaproic acid" or any other medicines;
• The patient takes factor IX, factor IX complex or anticoagulant complex;
• Tendency to thrombosis;
• Pregnancy, the patient plans to become pregnant or breastfeed.

What to do if the drug is missed

In this case, you need to take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing regimen. Do not take a double dose to make up for the missed one.

What are the side effects?

"Aminocaproic acid" can also cause side effects. It:

• nausea;
• Vomiting;
• Abdominal pain or cramping;
• diarrhea;
• Black, tarry stool;
• Bleeding from the gums;
• headache;
• dizziness;
• Confusion;
• Hallucinations;
• Swelling of the hands, hands, feet, ankles or legs;
• Deterioration or blurred vision;
• tinnitus.

Some side effects can be severe. If you experience any of these symptoms, you should urgently cancel the drug:

• rash;
• Itching;
• Difficulty breathing or swallowing;
• Muscle weakness;
• fatigue;
• dyspnea;
• Pressing or compressive pain in the chest;
• Unpleasant sensations in the hands, shoulders, neck or upper back;
• Increased sweating;
• Feeling of heaviness, pain, heat and / or swelling in the legs or in the pelvis;
• Sudden tingling, cold in the hands or feet;
• Difficulties with speech;
• Sudden drowsiness;
• Sudden weakness or numbness in the hands or feet;
• Rapid breathing;
• Sharp pain with deep breath;
• Increased or slowed heart rate;
• Coughing up blood;
• Urine color rust;
• Decrease in the amount of urine;
• Fainting;
• Convulsions.

Such side effects can cause and Traneksam. Similar tablets "Aminocaproic acid" can also lead to such complications. Some patients may experience side effects, which usually do not require medical intervention. They may disappear during the treatment. The doctor should warn about ways to prevent or reduce some of these side effects.

Incompatibility and treatment control

The drug is incompatible with the antibiotics of penicillin, tetracycline, erythromass, antihypertensive agents, "Diazepam", "Dipiridamol". With simultaneous use with hemostatic drugs, the effect of thrombus formation is potentiated.

It is very important to monitor the process of blood clotting during the administration of the drug. For this, it is necessary to take blood tests to see that the medicine is working properly and there are no undesirable effects.