"Butadion" (tablets): instructions for use, analogues, price and reviews

What is the purpose and how to use the medicine "Butadion" (pills)? Instructions for use, indications, properties and features of this drug will be presented in this article.

Also in it you will find information about how much it costs, what ingredients are included in its composition (active and inactive) and whether it has side effects.

Composition and packaging of medicament

What components are contained in the preparation of Butadion? Tablets include an active substance such as phenylbutazone. Also in the composition of the drug include: potato starch, impellose, magnesium stearate, sodium bicarbonate, talc and silicon dioxide.

The drug "Butadion" (tablets) goes on sale in blisters, which are enclosed in cardboard packages.

Pharmacodynamic characteristics of the medicinal product

Do you know what a drug like Butadion is? Experts say that this is a non-steroidal anti-inflammatory drug that has antipyretic and analgesic effect.

The effectiveness of this agent is related to its ability to suppress the activity of cyclooxygenase. As a result of this effect, synthesis of prostaglandins is slowed down.

The drug in question enhances the reverse absorption of salts and water in the tubules of the kidneys. It also eliminates pain syndromes and reduces swelling, which often accompanies inflammatory processes.

How does the therapeutic effect of Butadion appear? Tablets reduce pain in the joints (during motion and at rest), and restore their mobility or increase the volume of movements.

The anti-inflammatory effect of this remedy in many respects surpasses the effect of the analogous preparation "Amidopyrin".

With gout, this medicine doubles urate output along with urine, and also reduces their amount in the blood.

It should also be noted that the drug "Butadion" (tablets), the instruction for which is enclosed in the package together with blisters, reduces pain and signs of inflammation in thrombophlebitis (postoperative and hemorrhoidal veins).

Kinetic features of the preparation

Where is the drug Butadion absorbed (tablets)? The instruction says that the high absorption of this medicine comes from the digestive tract. Its bioavailability is about 87-90%, and the maximum concentration in plasma is observed after 60-150 minutes after administration.

From blood, the drug gradually passes into tissues and organs, and also penetrates into the cavities of the joints and through the blood-brain barrier.

The metabolism of this agent is carried out in the liver. Its half-life is 19-25 hours. Drug is withdrawn through the kidneys and through the digestive tract.

Indications for taking tablets

In what cases is the drug "Butadion" prescribed? Tablets are effective in treating:

• Bekhterev's disease;
• Osteoarthritis;
• Psoriatic arthritis ;
• Rheumatoid and lupus arthritis;
• Bursitis and tenosynovitis;
• Gouty arthritis ;
• Algodismenorei;
• Postoperative pain syndrome;
• Dental and headache.

Also this medicine is used to stop unpleasant sensations in neuralgia, burns and radiculitis.

Contraindications to taking medication

How much is the drug we are considering? What is its price? "Butadion" can be purchased at any pharmacy at a very reasonable cost. We will present it at the very end of the article.

Are there any contraindications for this medicine? According to the instruction, this medication is forbidden to use at:

• Bleeding from the digestive system in history;
• Acid intolerance to acetylsalicylic;
• Heart rhythm disturbances;
• Hypersensitivity to phenylbutazone;
• Oppression of the bone marrow;
• Exacerbation of ulcerative colitis and peptic ulcer of the gastrointestinal tract;
• Decompensated CHF;
• Hepatic and renal insufficiency;
• Hyperkalemia;
• Under the age of 12;
• Pregnancy, especially in the first and third trimesters;
• Simultaneous administration of other drugs that contain phenylbutazone.

Instructions for the use of the drug "Butadion"

According to the instructions, the drug "Butadion" is taken orally after meals, 150 mg four times a day. The largest single dose of this drug is 200 mg, and the daily dose is 600.

The duration of therapy with this drug depends on the severity of the disease and the patient's condition. The dose of the drug, equal to 400-600 mg per day, is able to reduce the amount of urine in diabetes insipidus.

Teenagers from 12 years old tablets "Butadion" appoint 75 mg three times a day. In order to prevent the irritant effect of this drug on the gastric mucosa, it is recommended that it be washed with warm milk.

In the presence of joint diseases, the effect of the medication is enhanced by the simultaneous administration of "Prednisolone" (drip, intravenously).

It should also be noted that, to increase the therapeutic outcome, Butadion tablets are combined with Butadion ointment.

Side effects after taking pills

Reception of tablets "Butadion" can cause the following systemic reactions:

• Nausea, abdominal pain, dyspepsia;
• Vomiting, aphthous stomatitis, heartburn;
• Ulceration of the mucous organs of the digestive tract, diarrhea, tinnitus;

• Gastrointestinal bleeding;
• Bleeding gingival and hemorrhoidal;
• Increased blood pressure;
• Impaired liver function;
• Headaches, anemia, depression, leukopenia, dizziness;
• Drowsiness, agranulocytosis, agitation, thrombocytopenia.

Side effects from the blood require withdrawal of the drug and treatment to a narrow specialist.

The delay in water and sodium in the body, associated with the reception of Butadion, significantly worsens the condition of patients with hypertension and CHF. This point also requires an adjustment in the treatment.

Similar medicines and price

"Butadion" in tablets (20 pieces) can be purchased for 40-70 rubles.

As for the analogues, the following means are used as such: "Butadione-OBL", "Artrisin", "Phenylbutazone", "Butalidone".

Patients' comments about the drug

Now you know what the price for the drug "Butadion" is. Tablets are inexpensive, but as for the reviews, they will be presented below.

Analyzing the responses of patients about this drug, we can safely conclude that it effectively manifests itself in any joint and muscle pain. But, in addition to positive feedback, patients often make negative reports about him. According to them, tablets "Butadion" quite often cause complications from the organs of the gastrointestinal tract and blood. In this regard, most doctors recommend that you stop taking this medication and replace it with a safer means.