"Arifon retard" means. Instructions for use

The drug "Arifon retard" belongs to the category of antihypertensive (diuretic) drugs, derivatives of sulfonamide. The active ingredient is indapamide hemihydrate. The drug helps increase the release of chloride ions, sodium, to a lesser extent - magnesium and potassium ions - in the urine, which is accompanied by an increase in diuresis. The drug has antihypertensive effect in dosages that do not exert a pronounced diuretic effect. Activity of the drug is also associated with the ability to lower the OPSS and increase the elasticity of arterial walls. The medicine provokes a decrease in hypertrophy in the left ventricle of the heart. On the basis of monotherapy, the antihypertensive effect of the remedy is noted throughout the day after administration.

Medication Arifon retard. Indications for use

It is recommended for hypertension.

Contraindications

No medication is prescribed for hepatic encephalopathy, insufficiency of renal activity of severe course, hypokalemia. The medication "Arifon retard" is not recommended (the instruction on the use warns about it) simultaneously with the means, contributing to the prolongation of the QT-interval. Contraindications include individual intolerance of components. The medicine is not prescribed during the prenatal period and during lactation. It should be taken into account that the medication is capable of provoking fetoplacental ischemia, leading to abnormalities in fetal development.

Dosing regimen

The drug is taken per tablet per day. It is advisable to drink the medicine in the morning.

Medication Arifon retard. Instructions for use. Side effect

On the basis of therapy, it is likely that the concentration of potassium decreases and hypokalemia occurs against this background (in particular, this phenomenon can be expressed in patients at risk). Patients may also experience hyponatremia, complicated by hypovolemia, orthostatic hypotension, dehydration of the body. In rare cases, there is an increase in the content of calcium in the body. During the reception of the Arifon retard (instructions for use indicate this), pancreatitis may develop, dry mouth, thrombocytopenia, anemia (hemolytic, aplastic including), an increase in glucose and urea in the plasma, constipation, nausea. On the grounds of intolerance, allergic skin manifestations in the form of rashes, itching, burning or irritation of the cover are likely. In rare cases, exacerbation of lupus erythematosus of the disseminated type, asthma attacks, hemorrhagic vasculitis can be observed . Some patients have asthenia, dizziness, paresthesia, headaches. As a rule, these effects are eliminated when the dosages are lowered. In the presence of liver failure with the medication "Arifon retard" (instructions for use warns about this), the risk of developing hepatic encephalopathy increases .

additional information

When administering therapy to patients with diabetes mellitus, careful monitoring of the glucose level should be provided.