Analog "Prestanza". Medication "Prestans" and its analogues, reviews

Angina pectoris, ischemic heart disease and hypertension are those diseases that in our time increasingly affect people. The reason for this is the rapid pace of life, constant stress and many other factors. In order to stabilize the work of the heart muscle, doctors often prescribe the drug "Prestan" and its analogues. But before proceeding to consider the substitutes for this medication, you need to familiarize yourself with its characteristics and properties.

Pharmacological characteristics of the drug

This combined drug belongs to the group of calcium channel blockers and ACE inhibitors. Its complex action is due to the presence of two main active components. The first - perindopril - is responsible for the inactivation of bradykinin. The consequence of this effect is the inhibition of ACE. At the same time, patients have a decrease in both systolic and diastolic pressure, as well as improvement of peripheral blood flow, vasodilatation, restoration of elasticity and structure of the arteries.

As for the second active ingredient of the drug, it is amlodipine. This substance belongs to the dihydropyridine group. It blocks slow calcium channels due to the fact that it activates the process of inhibiting the transmembrane transition of calcium ions into smooth muscle cells and cardiomyocytes of the vascular wall. Any analogue of "Prestans", which includes amlodipine, causes the expansion of peripheral arterioles, as well as reduces the need for oxygen in the myocardium.

Form of release of medicine and contraindications

It is worth recalling that this medication is prescribed for ischemic heart disease and arterial hypertension. However, there are a number of ailments in which the drug is categorically contraindicated. So, do not prescribe the drug for cardiogenic shock, unstable angina, renal failure, aortic stenosis and others. It should also be noted that any analogue of Prestans, which contains amlodipine and perindopril, is prohibited for idiopathic and hereditary angioedema edema, during pregnancy and lactation, as well as for lactase deficiency, hereditary lactose intolerance and patients under 18 years of age.

As for the form of release of the drug, it is only one - tablets. However, it should not be forgotten that the medicament consists of two main components. It is this fact that the manufacturer took into account and reflected the ratio of the active substances content with the help of the tablet form. In the oblong - 5 mg of each substance, in square (5/10) - 5 mg of perindopril and 10 mg of amlodipine, in triangular (10/5) - on the contrary. But the round contains 10 mg of each active ingredient.

Analogs means

Of course, those people who suffer from chronic ischemic heart disease or hypertension, know what are the analogues of the "Prestans" tablets. For those who first encountered the aforementioned ailments, it is necessary to understand this question a little. But first it is worth noting that this information should not be taken as a guide to action and self-replacing the medication prescribed by the doctor.

To date, the only structural analogue of "Prestanza" is the tablets of "Dalneva". However, the same group can include and drugs such as "Amlodipine" and "Perindopril." As for the drugs that are similar to the drug "Prestan" for pharmacological action, their list is much larger. And the leading positions in this list are taken by such drugs as Equator, Enanorm, Triapin, Koripren, Ecuquard,

We will familiarize ourselves with each of the above medicines in more detail. But first it is necessary to say that, like the drug "Prestan", analogs, generics, are released from pharmacies only on prescription.

Daneva tablets

The main active ingredients of this medication are perindopril and amlodipine, as in the "Prestan" drug. The only distinguishing feature of these two medicines is the ratio of the main active ingredients. So, tablets of "Dalnev" are issued with a dosage of 5: 4, 10: 4, 5: 8 and 10: 8. The first digit corresponds to the amount of amlodipine, the second, respectively, indicates how much perindopril is contained in 1 tablet. If you draw an analogy, you can say that the tablets "Dalnev" with a dosage of 5/4 - it's almost identical analogue "Prestanas 5/5". However, what exactly ratio of the main active substances to the patient will be the most effective and safe, should only be determined by the doctor.

Reviews about the drug

Most people who took this medication are very happy with the result of the treatment. Due to the mild action of the drug in patients, there is a gradual decrease in pressure. Also, the benefits of the drug include the absence of withdrawal syndrome and the duration of the action. Based on the above, we can conclude that the tablets "Dalnev" - a cheap analogue of "Prestanza", which is not inferior to the pharmacological effect.

Despite the worthy list of benefits, there are those patients who are very categorically negative about the drug. And most of these people have experienced the side effects of the drug.

Amlodipine and Perindopril

Despite the fact that in the preparation "Prestanz" instructions for use, analogues such as "Amlodipine" and "Perindopril" does not mention, they deserve attention.

It is probably meaningless to talk about the pharmacological action of each of these medicines. Suffice it to recall that they are both part of the "Prestans" facility. Since each medication is issued separately, the physician can in each case choose the individual component ratio necessary for the treatment of the patient. In addition, if a patient is contraindicated in one of the medicines, then he can only confine himself to taking the second, without harm to his health. Therefore, considering the drug "Prestans", analogues, such as "Perindopril" and "Amlodipine", must be studied.

Equator

This antihypertensive medication also consists of two active components. The first, as in the drug "Prestans" is amlodipine, the second - lisinopril. And if we have already familiarized ourselves with the pharmacological characteristics of one component, then a few words should be said about the second one. First, this substance contributes to a decrease in OPSS, a decrease in blood pressure and pressure in the pulmonary capillaries. Secondly, lisinopril increases the tolerance of the myocardium to the increased stress in people suffering from heart failure. And, thirdly, this component of the drug helps to expand more arteries than veins. Thanks to such a complex action on the body, this analogue of "Prestans" is effective with essential arterial hypertension.

The drug is available only in a tablet form with a dosage of 5/10 mg and 10/20 mg (lisinopril / amlodipine).

Reviews about the drug

Most positive reviews of patients are due not only to the effectiveness of the drug, but also to its other positive characteristics. So many people say that the drug very gently stabilizes blood pressure and maintains the condition for a long time. And even though the medication has a large list of side effects, they occur very rarely.

Negative response is mainly only those patients whose body has reacted negatively to taking the medicine. In addition, like the drug "Prestans", the instruction for the use of analogs recommends taking in accordance with a clear dosing system. An independent increase or decrease in the dose of the drug can cause a worsening of the patient's condition and lead to many negative consequences.

Means "Enanorm"

It is a combined antihypertensive drug consisting of two antihypertensive agents with a complementary mechanism for reducing blood pressure: enalapril - ACE inhibitor and nitrendipine - a blocker of slow calcium channels. Indications for its use is essential hypertension (that is, the drug is prescribed for patients who require combination therapy).

Like Prestan, analogues of Russian and foreign have a rather impressive list of side effects. And more often it is with this fact associated negative reviews of people who use antihypertensive drugs. And the medicine "Enanorm", unfortunately, does not apply to exceptions.

In most cases, patients respond positively to the drug and are satisfied with the results of treatment received.

Means of "Triapin"

With arterial hypertension of moderate severity, a doctor can appoint not only an analogue of "Prestanas 5/5". And most often in such situations, the specialist recommends the patient the drug "Triapin", the main active components of which are ramipril and felodipine. This drug effectively reduces blood pressure and is valid for 24 hours. The therapeutic effect is observed after 60-90 minutes after the application of a single dose. The duration of the course of treatment is 21-28 days, after which the blood pressure stabilizes for a long period of time. The need for a repeated course of treatment of this remedy can be judged only by the attending physician in each case.

Reviews about the medicine

To the advantages of the remedy, which patients mark, it is possible to attribute a rapid hypotensive effect and duration of action of the medication, which allows taking the tablet only once a day. In addition, many patients note that this analogue of "Prestanas 10/5", with compliance with the dosing system, very rarely causes adverse reactions and is well tolerated.

But those who are not very flattering about the facility, justify their opinion is the presence of many side effects, some of which they experienced on themselves.

The preparation "Koripren"

With essential hypertension, doctors recommend that patients take Prestans 10/10. Analogues can also be effective in such situations, and one of them is Koripren. The composition of this product includes two active substances. First, the ACE inhibitor is enalapril, the second is lercanidipine, which belongs to the group of slow calcium channel blockers. Thanks to this complex composition, the drug lowers blood pressure.

The preparation is produced exclusively in tablet form. But the dosage is calculated only by the doctor, taking into account the nature and severity of the disease, as well as the individual characteristics of the patient.

Reviews about the medicine

The negative attitude of patients towards the drug is explained by the presence of a large number of contraindications and side effects, as with the "Prestans". Instructions for use, reviews of analogues are recommended to be used only for the purpose of the attending physician, who will choose the safest and most effective dosing system. Only in this way it is possible to avoid the negative influence of the medication on the body and to bring the state of health back to normal. And practically all who listened to these recommendations are very pleased with the result of the treatment and are positive about the drug "Koripren".