BeautySkin care

A group of retinoids: drugs. Retinoids: what is it?

Among the most common cosmetic problems, acne occupies leading positions. They appear regardless of age. In young people, they appear as a reaction to puberty. But any adult person pimples up with strong experiences, overeating or skin problems. Here also it is necessary to have in the arsenal some favorite means on struggle against spots. Recently, you can often hear about retinoid drugs and their effectiveness.

What is it?

It would be nice to be beautiful, but not always it turns out. Say, going to an important date or a business meeting, where you need to be at the parade, and here a pimple star in the forehead burns. What should I do? Of course, fight, and with effective methods! To them, rumor refers to retinoid drugs. If you consult a doctor, he can advise the use of retinol acetate or retinol palmitate. These drugs and contain retinoids, which, in fact, are analogs of vitamin A. Otherwise it is called retinol. In the body, this substance is synthesized independently from the beta-carotene that comes with food. If beta-carotene is of animal origin, then the substances are called retinoids. With plant origin, these are carotenoids.

The Importance of Vitamin A

In many of the key processes in our body, vitamin A. takes part. Accordingly, its deficiency adversely affects the regeneration of cells, the formation of bones, nails and teeth, the work of the brain, visual organs, as well as the condition of the skin and mucosa. But the difficulty is that a large number of people assure others that taking vitamins can not bring harm to the body, and therefore one can take uncontrolled preparations containing retinoids. But the situation is completely different, especially if we mean retinol of synthetic origin.

In dermatology

Dermatologists can prescribe retinoid drugs in exceptional cases, when all the means have been tried, and acne has not passed. In this case, various dosage forms can be prescribed: for oral administration, as intramuscular injections, creams or preparations for external use. In rare cases, a specialist can recommend adding a moisturizing cream to a couple drops of retinoids. Some retinoid drugs can be purchased at a pharmacy, for example, retinol acetate or retinol palmitate. By consistency, these substances are oily liquids. These two drugs are very different. The first in the human body is not contained and, in fact, is a salt of acetic acid. And the second is a physiological saturated acid, which, after decomposition, transforms into unsaturated acids, necessary for the life of the organism.

Who should be pricked up?

If used as a drug for the treatment of acne retinoids, then you need to take into account and existing contraindications. For example, pregnant and lactating women, as well as people with hypersensitivity to the skin, liver and allergies, should refrain from taking such drugs. Also, do not risk heavily smoking and drinking people. Especially considerate should be young pregnant women, since retinoids for acne are drugs that are unacceptable at this time. They can cause developmental defects in the fetus.

Side effects of drugs

Immediately before taking it, you need to know that in such a tool contains 20 times the daily norm of retinol. Such an overdose can not be safe. Testimonials confirm the fact that taking retinoids causes negative consequences. These are defects of the fetus, if the medicine is taken by a future mother, a serious allergic reaction, if the reception takes place during the active sun. Slightly less serious problems, but still unpleasant, imply a strong skin itch, redness and peeling of the skin. Skin can become dryish. Hair loss and eyebrows are sometimes observed. Probably, enough arguments are given, in order to abandon self-treatment retinoids. Many doctors do not recommend them at all, saying that it is best when they enter the body with food.

How retinoids treat acne?

The most effective are the treatment of acne retinoids. Preparations of this type normalize the process of keratinization of the follicular epithelium and reduce inflammation. As an example, we can mention "Adapalen", which is a synthetic analogue of retinoic acid and is produced not only as a cream, but also as a gel. "Adapalen" blocks the formation of comedones and removes existing ones. By inhibiting the migration of leukocytes in the center of the inflammatory process, an anti-inflammatory effect is achieved. Apply the drug on the affected skin every day before going to bed, avoiding the area of the lips and eyes. The effect is noticeable after a month or two of regular treatment. A persistent improvement is evident after a three-month course. Among the pimples of topical retinoids, there is dry skin, irritation of the mucosa. In the sun, skin irritation can occur, since this group of retinoids is thinning the skin.

In addition, retinoids include tretinoin, isotretinoin, etretinate, acitretin, tazarotene and temarotene. To topical, in other words - external means include "Effezel", "Klensit", "Differin", "Izotreksin", retinoevuyu ointment, "Adaklin" and "Radevit." Capsular analogues include "Roaccutane", "Acnekutan", "Aevit" and "Tegison".

By groups

There are four large groups or generations of retinoids used to control acne, wrinkles, aging and pigmentation.

  1. The first generation includes retinol and its ethers. This is the most effective in the fight against acne, a group of retinoids. The drugs are retinol acetate, retinol palmitate, Retinal, Tretinoin and others.
  2. The second generation covers systemic drugs for the treatment of psoriasis and dermatosis. These are drugs such as etretinate and acitretin. In pharmacies, they are found under the names "Tigazon" and "Neotigazon."
  3. In the third generation, retinoids are used in oncology practice. They are represented by polyaromatic compounds (arthinoids).
  4. The fourth generation of retinoids included selective species, recently synthesized. These are "Tazaroten" and "Bexaroten". The former is used exclusively as a gel and effectively treats psoriasis.

The action of retinol on the skin

Local retinoids are topical preparations that have a positive effect on the skin of the body. Thus possible pobochki are minimized, as to reach "overdose" at such variant it is improbable. Treatment of blackheads with such drugs is several times safer. For external treatment of acne, both natural and synthetic retinoids are used. To natural are isomers of retinoic acid - "Isotretinoin" and "Tretinoin". The latter is more used abroad and is not used in Russia, as it causes severe skin irritation. Synthetic drugs include the already mentioned "Adapalen" and "Tazaroten".

Scientists have proven that retinol, or vitamin A, promotes skin regeneration, neutralizes the effect of free radicals. In addition, it stimulates all cells to regenerate, including even old and sick. Vitamin A protects the skin from wrinkles due to the artificial synthesis of collagen and elastin. With the regular use of retinoids, the risk of photoaging is eliminated and the upper layer of the epidermis is renewed.

Choosing a cream with retinol, you need to pay attention to the concentration. Retinol is whimsical in its essence, and without protection it collapses. Therefore, it is "hidden" in capsules, which must be opened before application.

For the skin prone to inflammation and irritation, the drug in the form of a gel is more suitable.

Myths and truths

Approaching the conclusion, I want to note that the retinoids are very unstable. Preparations, whose names were announced, have already proved themselves well and proved their effectiveness, but many others behave differently to each individual. Therefore, to state with confidence that retinoid drugs will help you, you can not.

At the same time you need to dispel other myths about retinoids. For example, skin moisture is not the main condition for effective application. Despite the recommendations to apply the drug before bed, it can also be used in the daytime, but only after the skin has become accustomed to retinol. For protection, it is better to apply sunscreen. Another myth says that the skin around the eyes is a forbidden area for their application. This is not quite true, although the skin here is really the most delicate. If you carefully process this site, then no trouble will not follow. Naturally, you do not need to go very close to the eyelids and do not treat the skin of your lips.

The result is this: funds with retinoids quite effectively eliminate the signs of withering of the skin, if you observe all the precautions and technique of application. Ideally, you must first undergo the procedure under the supervision of a professional. And if he entrusts you with independent exercise of care, then only it is necessary to pass to partial self-treatment. This is provided that the drugs are used in the form of gels, creams or capsules that need to be added to creams. Remember that oral administration can be dangerous with uncontrolled treatment!

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