The medicine 'Physiotenses'. Instructions

The drug "Physiotenses" (synonyms: "Moxogamma", "Moxonidine") is included in the category of antihypertensive medications. They have a central effect. The active substance is moxonidine.

The "Physiotens" tool refers to the clinical and pharmacological group of selective antagonists of imidazoline receptors.

Decrease in diastolic and systolic pressure with prolonged and single application is caused by a decrease in the pressor effect of the nervous sympathetic system on peripheral vessels, a decrease in peripheral resistance. At the same time, the frequency of contractions and cardiac output are not significantly altered.

After taking the drug is absorbed by 90% of the digestive system. The maximum concentration in the blood of the drug reaches sixty minutes later.

The drug "Physiotenses" instruction recommends taking with arterial hypertension.

The use of the drug is not dependent on food intake.

The initial dosage of the preparation "Physiotenses" instruction recommends setting no more than 200 mcg / day.

Single dosage should not be above 400 mcg, a day should not take more than 600 mcg (divided into two applications).

Patients on hemodialysis and who have renal failure are prescribed a minimum therapeutic dosage of 200 μg. In a day, these patients should not take more than 400 mcg.

The abolition of the drug "Physiotenses" instruction recommends the exercise, gradually lowering the dose.

With the use of a medicine, development of negative manifestations is possible. During treatment, sleep disorders, nausea, drowsiness, dry mouth, headache, angioedema, dizziness may occur. Taking medication can provoke orthostatic hypotension, excessive sharp lowering of blood pressure, skin rash, peripheral edema, asthenia.

As practice shows, these effects are eliminated gradually after the first weeks of therapy. If negative reactions persist or worsen, you should consult your doctor. You may need to cancel the medicine.

The drug is not prescribed in the syndrome of weakness in the sinus node (SSSU), severe bradycardia, patients under the age of eighteen (due to the limited clinical experience), as well as hypersensitivity.

With care, the drug "Physiotenses" is prescribed for kidney failure in chronic course, as well as with severe liver failure.

In connection with the poorly understood influence of the "Physiotens" medication on the fetus and pregnant woman's condition, it is the doctor who determines the appropriateness of the appointment during gestation. It was found that the active ingredient - moxonidine - is secreted into breast milk. In this regard, if necessary, to prescribe to a woman feeding the drug "Physiotenses" should warn the patient about the termination of natural feeding.

Despite the fact that there is no data on the negative impact of the drug on the ability to manage transport, mechanisms and other equipment, one should remember about the likely occurrence of dizziness and drowsiness during therapy.

If necessary, stop taking the drug "Physiotenses" and simultaneously taken beta-blockers first cancel the last, and then (after several days) the medicine "Physiotenses".

During the whole therapy, ECG, heart rate and blood pressure should be monitored.

It is not recommended to administer tricyclic antidepressants simultaneously with the medicine "Physiotenses".

The medication is allowed to be used together with thiazide diuretics, as well as ACE inhibitors.

Before you start taking the drug "Physiotenses", analogues of the medicine (for example, the drug "Moxoniteks"), you need to consult a doctor.