Medication "Vazilip" instructions for use refers to lipid-lowering drugs (used to reduce cholesterol). The main component - simvastatin - takes part in the synthesis of cholesterol by the hepatic cells. is he Reduces the content of said substance in general, serum triglycerides and low-density lipoproteins. The tool "Vazilip" (instruction for use on this testifies), among other things, normalizes the functions of endotheliocytes, while atherosclerotic process slows down migration, cell proliferation, performs the function of an antioxidant.
Indications for use
The drug "Vazilip" is used for hyperlipidemia, both primary and hereditary (polygenic and heterozygous hypercholesterolemia, mixed and monozygotic hyperlipidemia). Also, the drug is used in the case of coronary disease, when the total cholesterol level in the blood rises.
Form of issue and composition
The production of medicament is carried out in the form of tablets intended for oral use. One tablet contains the active ingredient in an amount of 10, 20, 40 mg. Additional constituents are citric acid, titanium dioxide, hypromellose, magnesium stearate, lactose monohydrate, ascorbic acid, starch, propylene glycol, microcrystalline cellulose, butylhydroxyanisole.
Method of use
When hypercholesterolemia take the drug "Vazilip" instruction for use advises once a day (in the evening) in an amount of 10-80 mg. The initial dose is 10 mg, after a monthly intake it is gradually increased. The greatest daily dose is 80 mg. You can drink tablets, regardless of food. In the case of hereditary hypercholesterolemia (homozygous), the dosage per day is 40-80 mg. With IHD, take the drug "Vazilip" instruction for use initially advises on 20 mg per day. The highest daily dose is 40 mg. Patients with renal insufficiency in severe form are recommended to take no more than 10 mg of medication per day. Increase the dosage is allowed only with a strong need and only if the doctor will constantly monitor the treatment process.
Side effects when using the drug "Vazilip"
Patients' reports indicate good tolerability of the medication. Nevertheless, some people note the appearance of unpleasant effects during the use of the drug, such as nausea, pancreatitis, constipation / diarrhea, abdominal pain, depression, headache, sleep disorders, peripheral neuropathy, high fatigue, muscle weakness and dermatomyositis. Rarely rhabdomyolysis develops in very rare cases. Allergic reactions may occur: vasculitis, skin rash, eczema, redness of the skin, angioedema. Usually, all listed negative phenomena, if they appear, are of low severity and quickly pass.
Contraindications
With liver diseases that are acute, high sensitivity to the ingredients included in the ingredients, the drug "Vazilip" is not prescribed. Also it is not used by pregnant and lactating women.