"Spytomin" preparation: instructions for use, indications, contraindications

Today we will tell you about such a preparation as "Spitomin". Instructions for use, price, reviews, analogues and its features - all these points are of interest to patients to whom the doctor prescribed this medicine. You will find all the necessary information in the article.

Description of the drug, its form, packaging and composition

What is the medicine "Spitomin"? Instructions for use (the description of the drug in it is presented in great detail) states that these tablets are white, odorless, round and flat, with a facet, and also with a risk and engraving "E151".

This agent contains buspirone hydrochloride and such auxiliary components as carboxymethyl starch, lactose monohydrate, sodium magnesium stearate, microcrystalline cellulose and colloidal anhydrous silicon dioxide.

On sale this medicine comes in blisters and cardboard packs.

Operating principle

What are the features of the drug Spitomin? Instructions for use (the price of the tablets is presented below) states that this is an anxiolytic agent that belongs to the non-benzodiazepine series and has an antidepressant effect.

Unlike other anxiolytics, this drug has no antiepileptic, sedative, hypnotic and muscle relaxant properties. Its principle of action is based on the effect of buspirone on the dopaminergic and serotonergic systems.

This drug selectively blocks dopamine receptors (presynaptic) and increases the rate of excitation of neurons (dopamine) of the midbrain.

What other properties are inherent in the drug "Spitomin"? Instructions for use asserts that buspirone is a selective partial agonist of 5-HT1A-serotonin receptors. It does not affect benzodiazepine receptors and GABA binding, nor does it affect psychomotor functions and does not cause tolerance. In addition, this agent does not potentiate the action of alcoholic beverages.

The therapeutic effect of the drug in question develops gradually and is observed one or two after the start of treatment.

Kinetics of the agent

Absorption of the drug "Spitomin", the instruction for use of which is presented below, occurs in the digestive tract. Buspirone is extensively metabolized when passing through the liver. Its bioavailability is 4%, and the highest concentration in plasma is reached after an hour.

Buspirone is excreted together with milk. Information on the penetration of this drug through the placental barrier is absent.

A drug with feces is excreted for five hours.

Indications

What is the purpose of the Spitomin tablets? The instruction for use indicates the following indications:

• Syndrome of autonomic dysfunction;
• Anxiety disorder generalized;
• Abstinence syndrome alcoholic (in the form of ancillary therapy);
• Panic disorder ;
• Depressive disorders (in the form of ancillary therapy).

Contraindications

In what cases is it not recommended to use tablets "Spitomin"? Instructions for use indicate the following pathologies and conditions in which the medication is contraindicated:

• glaucoma;
• Hypersensitivity to the ingredients of the drug;
• Myasthenia gravis;
• Renal failure severe;
• Underage age;
• Simultaneous administration of MAO inhibitors ;
• Lactation period;
• Period of pregnancy.

With caution, this agent is prescribed for cirrhosis of the liver and kidney failure.

Spitomin medication: instructions for use

Analogs of this drug will be presented below.

The agent should be taken at the same time of the day, before or after a meal.

The drug should not be used occasionally (on demand) to treat anxiety, since its therapeutic effect develops only after repeated use.

The dosage of this medication is selected individually. As a rule, it is 15 mg. It should be divided into 2-3 sessions.

The maximum single dose of the drug is 30 mg, and the maximum daily dose is 60 mg.

In elderly people, dose adjustment is not required. If the kidneys or liver are damaged, the medication should be used with extreme caution and in small doses.

Adverse events

Usually the medicine "Spitomin" is transferred well. Only in some cases, this tool causes certain violations:

• Chest pain, sleep disorders, fainting, dizziness, arterial hypotension, headache, arterial hypertension;
• Nervous excitability, cerebral circulation disorders, dysphoric reactions, decompensation of heart failure, hypersensitivity to noise, myocardial infarction, dysphoria, myocardiopathy, suicidal ideation, bradycardia;
• Depersonalization, cold intolerance, euphoria, claustrophobia, hyperkinesis, tinnitus, fear, itching in the eyes, apathy, red eyes, hallucinations, stuttering, confusion, psychotic disorders;
• Blurred vision, laryngitis, conjunctivitis, swelling of the nasal mucosa, a violation of taste sensations, a feeling of heaviness in the chest, disorders of the inner ear, hyperventilation, eye pain, lack of air, photophobia, epistaxis, increased intraocular pressure;
• Galactorrhea, nausea, thyroid damage, flatulence, bedwetting, anorexia, increased appetite, dysuria, salivation, menstrual irregularities, intestinal bleeding, delayed ejaculation, and others.

Price, analogues, reviews

The cost of this facility is about 600 rubles. If required, it is replaced with an analog such as Buspiron Sandoz.

Comments from consumers report that the drug in question is a good anxiolytic. However, it can only be taken for the purpose of a specialist, for a long time (not sporadically).