Risperidone: instructions for use. "Risperidone Organica": description, reviews, contraindications

Age, mental and behavioral changes can significantly complicate the life not only of a sick person, but also of his close environment. Treatment of psychogenic and other diseases is a complex process, but medicine does not stand still and is inventing more and more ways to deal with them. The main role in this is given to drug treatment. Tablets "Risperidone", analogues of which are very numerous, are one of the most popular drugs. What is their feature? How to take them and do they have contraindications? Can I use these pills for depression? The answers to these questions we will try to give in this article.

Forms and composition of the drug "Risperidone"

Tablets "Risperidon" are manufactured by several pharmaceutical companies under the same name and have almost the same composition. The main active substance of the drug is actually risperidone itself in the amount of 1, 2 or 4 mg (depending on the dosage). Each tablet is covered with a film intestine-soluble coat of white color. The form of the tablets is rounded, biconvex. In the cross section, two layers are clearly visible: external and internal. The composition of tablets "Risperidon" - in addition to the active ingredient - includes additional components: starch, silicon dioxide, magnesium stearate and MCC.

Tablets "Risperidone" and their analogues, including "Risperidone Organica", are packed in contour packs of 10 pieces each, which, in turn, are placed in cardboard boxes of 2, 3, 5 or 6 packs together with instructions for Application. In addition, the product is also available in dark glass jars, each of which can contain 20, 30, 50 or 60 tablets. Banks are also placed in boxes of cardboard along with the instruction.

How does the medicine work?

The active substance tablets "Risperidone" instruction refers to derivatives of bensoxazole, that is, neuroleptics. In addition to the antipsychotic effect, this drug has sedative, hypothermic and antiemetic properties. This is due to the ability of the active substance to block D2 receptors in mesocortical and mesolimbic systems and the vomiting center, and also to act on adrenoreceptors localized in the brain stem. Also, the compound has the ability to block dopamine receptors in the hypothalamus.

Due to such pharmacological properties, the drug "Risperidone", reviews about which are almost always positive, is able to suppress such symptoms of neurogenic disorders as delirium and hallucinations, aggression and automatism. Against the background of this, experts note that the drug has virtually no effect on motor activity, but at the same time suppresses the affective symptomatic manifestations of schizophrenia.

Distribution in the body and excretion

Assimilation of the active substance in the gastrointestinal tract occurs in a fairly short time and in the maximum amount. Eating does not affect this process. The maximum value of the assimilated active substance in the blood plasma reaches as early as an hour after taking the drug. The derivatives of risperidone (9-hydroxyrisperidone) are absorbed somewhat more slowly.

Regarding the distribution in the body of the drug "Risperidone" instructions for use indicate the penetration of the active substance both in various tissues and organs, and in the brain and breast milk. The connection with plasma proteins is about 90%.

The half-life of the drug occurs in two stages: within 3 hours about 70% of the compound is excreted by the kidneys unchanged, while 9-dihydrisperidone is excreted in almost a day. In elderly patients and those who suffer from kidney failure, the timing of excretion of the drug from the body is increased.

Use of the drug: indications and contraindications

Use the medicinal product "Risperidone" the instruction for use recommends in the presence of the following diseases or disorders in the body:

1. Acute or chronic form of schizophrenia.
2. Psychopathic disorders characterized by negative or productive symptomatic manifestations.
3. Mental illness, accompanied by affective disorders.
4. Dementia, which occurs with the appearance of outbreaks of anger and aggression, delusions and other psychotic symptoms.

In addition, the drug "Risperidone" is shown to children in adolescence, who have behavioral disorders (destructive inclinations), mental or mental retardation, as well as bipolar disorders and various manias. In these cases, the pills play a supporting role in the therapy.

There are significant contraindications to this drug, including increased sensitivity to the components of tablets. In addition, the medicine "Risperidone" is recommended for use with particular caution in the following diseases or conditions:

• Brain tumors and cerebral circulation disorders;
• Hepatic and renal failure in severe form;
• Violations of intestinal permeability;
• Heart diseases, including myocardial infarction, heart failure in chronic form, antrioventicular blockade and bradycardia;
• Drug overdose or dependence on them;
• Dehydration of the body;
• Parkinson's disease;
• Convulsions (at the time of prescribing or a history);
• Pregnancy and lactation.

In addition, it is not recommended to prescribe the drug "Risperidone" (tablets) from depression, which is expressed in a decrease in the patient's activity and propensity to suicide. Also, with caution appoint the drug to persons who are under 15 years of age.

Dosage and methods of administration

Dosage and methods of taking the drug depend on the patient's existing disease, the severity of its course and the presence of concomitant diseases or pathological conditions. All the necessary data on the use of the medicinal product "Risperidone" you can see in the table.

In case of any disease or condition, the daily dose of "Risperidone" should not exceed 16 mg.

Unwanted reactions and overdose

Another important factor that you need to know about patients undergoing the course of treatment with the drug "Risperidone" is the side effects that can appear during the taking of tablets. The probability of their appearance depends primarily on the individual characteristics of the organism. So, what can bother the patient?

Most often there are the following undesirable reactions from various organs and systems:

• Infections of the upper respiratory and urinary tract (especially in elderly patients diagnosed with "dementia");
• Headaches, sleep disorders, dizziness, drowsiness, and visual impairment;
• Dyspeptic disorders, pain in the epigastric region, nausea, dry mouth;
• Heart rhythm disturbances (tachycardia);
• Swelling of the nasal mucosa and Eustachian tube, as a result of which the patient feels congestion of the nose or ear, nosebleeds;
• Cough, rhinorrhea and shortness of breath;
• anemia;
• urinary incontinence;
• Swelling in the joints, changes in gait (especially in elderly patients), pain in the back and joints.

There are also a number of side effects that are relatively rare when taking Risperidone. The experts' comments indicate the following:

• Ear and eye infections;
• Viral infections affecting the entire body or localized;
• Respiratory tract infections, including bronchopneumonia, tonsillitis, bronchitis and tracheobronchitis;
• Onychomycosis and acrodermatitis;
• Distraction, anxiety, mania and hypomania, dyskinesia;
• Muscle rigidity, hyperthermia, increased sweating;
• Unstable fluctuations in blood pressure;
• epilepsy;
• Apnea, obstruction of the upper respiratory tract by phlegm (whistles during breathing, dysphonia, or wet wheezing);
• Increase or decrease in weight;
• Menstrual cycle disorders, lack of ejaculation, priapism, lack of sexual desire;
• Soreness of the muscles of the chest;
• Swelling of the skin, especially in the face, chills, thirst, flu-like conditions;
• Weakness in the arms and legs, a feeling of stiffness in the joints.

In the event of a strong adverse reaction to taking Risperidone, synonyms of the drug can not become a worthy substitute for the drug, since they contain the same active components. In this case, the specialist will pick up another drug, which includes other compounds, or offer additional medications to eliminate unpleasant symptoms.

Symptoms and treatment of drug overdose

In case of inappropriate dosage instructions, an overdose can occur in the larger side, which is expressed in a pronounced and persistent lowering of arterial pressure and disturbances of the heart rhythm (tachycardia). In addition, patients may be disturbed by drowsiness, sedation, respiratory disorders and extrapyramidal disorders.

Specific antidote for the drug "Risperidon" is not, so the treatment is aimed at eliminating the most pronounced symptoms. As a first aid, the patient needs to rinse the stomach and give activated charcoal and laxatives. With a decrease in blood pressure to critical levels, intravenous injection of adrenostimulants and infusion solutions will be required.

During the whole period, monitoring of cardiac activity is necessary to detect various kinds of heart rhythm disturbances. If they are found, therapy with appropriate medications is performed.

Special instructions for the use of the drug

When taking the medicinal product "Risperidone", the instruction for use advises to observe several important recommendations. This will help not only reduce the likelihood of side effects, but also improve the overall condition of the patient in the presence of concomitant diseases.

First of all, it is necessary to pay special attention to the dosage of the drug for those patients who have diseases of the cardiovascular system. In this case, it is necessary to begin taking the drug with minimal doses, gradually increasing them to the required values. The same recommendations apply in the case of hypovolemia, dehydration and cerebrovascular disorders.

Experts also recommend refraining from eating high-calorie foods and overeating as such. This is due to the fact that when treating the medicine "Risperidone" is high probability of gaining excess weight.

It is not recommended during the treatment of tablets "Risperidone" to engage in activities related to the management of vehicles and other mechanisms that require the patient to a high concentration of attention and rapid psychomotor reactions.

Interaction with other drugs

When prescribing the drug "Risperidone", the price of which will be considered further, its ability to interact with many drugs should be taken into account. In some cases, this may lead to unexpected and not very pleasant consequences. Thus, drugs that depressively act on the human nervous system, as well as ethanol in conjunction with "Risperidon" provoke such a state as additive inhibition of the functions of the central nervous system.

Some drugs, for example, many beta-blockers, all without exception tricyclic antidepressants are able to increase the concentration of active substance tablets "Risperidone" in blood plasma. The same property is possessed by the drug "Fluoxetine". "Carbamazepine", on the contrary, reduces the concentration of active ingredient "Risperidone" in plasma. With their joint appointment, constant monitoring of the patient's condition is necessary, as well as adjusting the dosage of the drugs.

Reviews

Reviews of the tablets "Risperidon Organica" and "Risperidon", the price of which is considered affordable for a wide range of consumers (an average of 170 rubles per package), can not be called negative. The effect that tablets have on various psychogenic or behavioral diseases is positively assessed by both specialists and patients. They also respond to analogues of this medicine, because in most cases the difference between them is only in value, and the composition is virtually the same (with the exception of auxiliary substances).

The only significant drawback of the "Risperidone" tablets (analogues for the active substance also fall under this definition) are a lot of side effects, which in some cases can affect the patient's quality of life not for the better. That's why experts recommend that when any undesirable reactions occur, you should contact your doctor to find a way out of the situation together with him.

So, we learned what tablets are "Risperidon". Instruction, price, analogs and adverse reactions of the organism were considered in detail in this article. In conclusion, I would like to recall that this drug is dispensed solely on the prescription of a doctor. The unauthorized administration and administration of tablets of this group may harm your health.