Preparation 'Proginova', instruction for use

The drug "Proginova" is released in the form of a dragée, the active substance of which is estradiol valerate (2 mg each). The drug belongs to the clinico-pharmacological group of antiplasmic agents of the estrogenic type.

Estradiol valerate is estrogen from the group of estradiols. The drug "Proginova", the instruction indicates, does not suppress the processes that ensure ovulation, does not affect the synthesis of hormones. Estradiol replenishes the natural deficiency of estrogen after menopause, restores the disturbed mental emotional state of a woman arising against the background of age-related changes in the body. Eliminates vegetative climacteric symptoms, which are manifested by hot flashes, increased sweating, insomnia, nervous excitability, irritability, palpitations, irregular heart rhythms. Dizziness, headache, decreased libido, muscle and joint discomfort also eliminate the "Proginova" pellet.

The instruction contains information that after taking this medication the functions of the mucous membrane of the urogenital system improve, dryness, irritation in the vagina and painful sensations during sexual intercourse disappear.

The optimal amount of estrogen in the drug helps to delay or stop bone loss during the postmenopause.

The "Proginova" dragee, the instruction indicates, is prescribed as a hormone replacement therapy for women who have had body disorders that appear against the background of climacteric changes; For prevention of osteoporosis.

It is recommended to swallow a dragee, without chewing, and to wash down with a liquid.

If the patient's menstruation does not stop at the time of prescribing, then during the 5 first days of the monthly cycle, the Proginova drug should be taken, as instructed, in combination with one of the progestins.

In each package are sealed 21 pills, which are calculated 21-money rate. The opening date for the next package is determined by a specialist gynecologist. If the doctor prescribes cyclic replacement therapy with hormones, it establishes a break in taking the Proginova drug for about a week. If continuous hormone replacement therapy is prescribed, the dragee is not interrupted, the new package is opened the day after the end of the previous one.

In some cases, menstruating women are assigned cyclic combined replacement therapy with Proginova. The instruction warns that gestagen in combination with estradiol should be taken from 10 days to 14 days; It is important to remember that the break between gestagine intake is 4 weeks.

If the doctor prescribes a continuous combined replacement therapy for menstruating women with the Proginova drug,   Then gestagen in combination with estradiol should be taken daily.

In the course of clinical trials, some undesirable effects that appeared after taking the Proginova pellet were identified.

Side effects:

• Change in body weight of patients;
• Decreased mood, anxiety, increased or decreased libido;
• Headaches, dizziness, migraines;
• Impaired vision, lens intolerance;
• Palpitation;
• Abdominal pain, nausea, dyspepsia, bloating and vomiting.

Other disorders in the body can be manifested by rash, itching, urticaria, acne, muscle spasms, gynecological bleeding, breast pain, swelling and general weakness, thrombosis, thromboembolism.

Against the background of prolonged use of hormonal drugs with estrogens, the risk of developing oncological diseases or endometrial hyperplasia increases.

When appointing an antiplasmic remedy, "Proginova" the doctor must take into account contraindications to the use.