"Nimesulide" - what is it? "Nimesulide": instructions for use, composition, analogues, reviews

In his entire life, a man often suffers from pain. They can chase the body for a very long time. This can be both a temporary headache and permanent pain in connection with certain diseases. There are cases when conventional analgesics do not help, and then comes to the aid of the drug "Nimesulide", which is a powerful antipyretic and analgesic.

Composition and form of release

This preparation is synthetic. The active substance is nimesulide. The drug has 4 forms of release. First of all, these are tablets, which contain 100 mg of active ingredient. Tablets are in blisters for 10 pieces, in a carton can be 1, 2 or 3 blisters. Also, Nimesulide is available in the form of a powder, from which it is possible to make a suspension. One packet contains 100 mg of active ingredient. In the carton box can be 30, 15 or 9 bags. In addition, this drug is in the form of a ready-made suspension, 5 ml in volume, containing 0.05 mg of nimesulide. Another form of Nimesulide is a gel that has a volume of 30 g.

pharmachologic effect

The drug "Nimesulide" is analgesic, anti-inflammatory, antiplatelet and antipyretic.

Indications for use

It should be remembered that this medicine does not affect the progression of the disease, it is intended for symptomatic treatment and reduces or relieves pain only for the period of its use. The drug "Nimesulid" is used for dental and headaches, as well as for certain diseases of muscles and joints. Such diseases are osteoarthritis, rheumatoid arthritis, arthralgia, myalgia, tendonitis, bursitis, algodismenorea and pain in the postoperative period. Also, indications for use are various infectious and gynecological diseases. Another drug is used for fever.

Contraindications

A fairly large number of contraindications have both a powder and a tablet of Nimesulide. Instruction for use determines exactly these:

- active gastrointestinal bleeding;

- erosion or ulcers on the mucous membrane of the stomach or on the duodenum;

- cerebrovascular bleeding;

- hemophilia or other causes of blood coagulability;

- Any inflammatory bowel disease with exacerbation, for example ulcerative colitis or Crohn's disease.

In addition, contraindications are:

- active liver disease or liver failure;

- heart failure;

- bronchial asthma;

- recurrent polyposis;

- kidney disease at the stage of progression or kidney failure;

Hypersensitivity to any components of the drug;

- Alcoholism and drug addiction.

Also forbidden to children under the age of 12 years, women who wait for a child or breastfeed, take Nimesulide tablets. The instructions for use show that this drug should be used with caution in patients who have cerebrovascular diseases, dyslipidemia, CHF, diabetes mellitus. Patients with bad habits and elderly people should also take the medicine with caution.

Application of the drug

"Nimesulide" in the form of tablets, suspension or powder is taken orally. The Nimesulide gel is applied to the skin in the area with painful sensations. Use of the drug is only possible for patients over 12 years of age. Tablets and suspension are applied 2 times a day (100 mg of active ingredient). The maximum dose of the drug is 400 mg. When using the drug in the form of a gel, it is necessary to apply it on the affected area of the body (not more than 3 cm) and rub it with light massaging movements. The gel should not be applied under the bandage.

When preparing a suspension of "Nimesulide" powder must be dissolved in 100-150 ml of water. Patients who have kidney failure should reduce the daily dose, it should be 100 mg of nimesulide. Older people do not need a dose reduction. It is necessary to follow certain rules when using Nimesulide. What is it, not everyone knows, so to avoid causing side reactions, it is necessary to drink this medicine with a large amount of water, and also to use the maximum dose per day for a very short time. With a minimum intake of the drug, the course of treatment can be continued for about 2 weeks. If you need long-term treatment, you should always see a doctor.

Adverse Reactions

When taking this medication, there may be a side effect. It can manifest itself as allergic, and other similar reactions. Side effects can cause both gel and powder, and "Nimesulide" -tablets. The instruction determines the possibility of such skin reactions:

- occurrence of itching and rash on the skin;

- increased sweating;

- dermatitis;

Erythema;

Swelling of the face;

- hives.

Possible reactions of the nervous system:

- nervousness;

- Feeling of fear;

- dizziness and headache;

- drowsiness and nightmares;

- encephalopathy.

Regarding the urinary system:

- dysuria;

- edema;

- Hematuria;

- kidney failure;

- retention of urine;

- oliguria;

- Hyperkalemia;

- An infrastructural nephritis.

There may also be a side effect on the digestive system:

- vomiting and nausea;

- diarrhea or constipation;

- pain in the abdomen, gastritis;

- flatulence;

- stomatitis;

- stomach ulcer;

- gastric bleeding.

Such undesirable reactions can provoke "Nimesulide" (tablets). The instruction shows that, as regards the hematopoiesis system, there can also be a side effect:

- thrombocytopenia;

- Anemia;

- Pancytopenia;

Eosinophilia.

Regarding the respiratory system, reactions such as:

- Shortness of breath;

- bronchospasm;

- asthma.

General weakness, tachycardia, hypertension, blurred vision and hypothermia are also possible.

Overdose

Overdose may increase the side effect. To bring the organism in order after an overdose of Nimesulide, it is necessary to rinse the stomach and take activated charcoal. It is necessary to constantly monitor the kidneys and liver.

Interaction with other drugs

Do not use with the inhibitors and GCS tablets "Nimesulide", the use in this case can lead to the development of gastric bleeding. Taking this drug with a diuretic is not recommended, as it is possible to disrupt renal hemodynamics. "Nimesulide" helps to reduce the bioavailability of furosemide. It also has the ability to replace furosemide and salicylic acid in plasma proteins. It is forbidden to use this medicine together with alcoholic beverages.

Special instructions

If improvement does not occur, it is necessary to stop using Nimesulide medication. What is this and why the medicine does not work, the doctor should explain and prescribe another remedy. It takes a very short time to take the maximum daily dose to avoid side effects. The drug should be discontinued if there is a fever or flu-like symptoms on the background of its administration.

The development of side effects most often occurs in the elderly, so it is necessary to monitor the patient's condition during the treatment with the drug Nimesulide. Analogues of this drug to elderly patients should also be taken with caution.

"Nimesulide" has a negative impact on the fertility of women. Therefore, do not take it during pregnancy planning. This drug has an effect on the central nervous system, so you should not drive a car. It is necessary to avoid activities that require increased concentration of attention.

Storage of the drug

"Nimesulide" must be stored in a dark and dry place. The temperature should not exceed 24 degrees. Do not use the medication after the expiration date, which is 48 months.

"Nimesulid." Analogues

This drug contains the active substance nimesulide, also this substance is contained in all the substitutes for this drug. The need for an analogue can arise for various reasons, for example, some substitutes contain a smaller dose of nimesulide, and some have many additional substances that give the drug a more pleasant taste and smell. Most often in pharmacies they offer such drugs instead of Nimesulide: Nimesulide Maxfarm, Naize, Nimesil, Nimika, Nimulid, Mesulide, Nemuxle, Cockstrual, Novolide, Prolid, Florida, Aulin, Aponil, Ameolin. Many of the listed drugs are available both in the form of tablets and powder, and in the form of a gel for rubbing into the skin.

Reviews about preparte

In general, reviews about this product are only positive. In addition, the price for it is quite affordable. Many patients believe that the best way to cope with the pain syndrome is Nimesulide. What is it, every adult person who has had to face with severe pain or high temperature knows. Many patients say that the drug almost does not cause side effects, some people think quite differently, indicating that after taking the medicine, he tends to sleep. Instruction on this warns and advises not to sit at the same time driving a car. Patients also highlight the fact that Nimesulide acts quickly and gently relative to its counterparts. But in any case, do not take the drug for a long time, and if this is necessary, you should consult a doctor and, if possible, replace it with a weaker drug, which includes nimesulide. What it is? The main active substance of many pain relievers.