Medication 'Vazonit'. Instructions for use

The drug "Vazonit-Retard" improves microcirculation and rheological properties of blood, has a vasoconstrictive effect. The active component - pentoxifylline - is a derivative of xanthine.

The drug "Vazonit" promotes the inhibition of phosphodiesterase and the accumulation of cAMP in smooth muscle cells of blood vessels, in the blood constituents, organs and tissues. The drug slows the aggregation of erythrocytes and platelets, increasing their elasticity. Characterizing the mechanism of action of the drug "Vasonitis", the instruction indicates its properties to reduce the plasma content of fibrinogen, to enhance fibrinolysis. This leads to a decrease in the viscosity of the blood. Along with this, rheological properties (fluidity) also increase. The drug helps to improve the flow of oxygen in the tissue in areas with circulatory disorders (in the limbs, kidneys, CNS, including). The medicine has a slight dilating effect on the vessels.

When administered orally, the active ingredient is uniformly and continuously released and absorbed from the digestive system. The maximum concentration of pentoxifylline and its metabolites is reached after three or four hours. The therapeutic concentration remains for 12 hours. Excretion is carried out by the kidneys.

The drug "Vasonit" instructions for use recommends for disorders in the peripheral circulation (with Raynaud's disease, diabetic angiopathy, obliterating endarteritis). Assign a medicine for angioedema, dyscirculatory and atherosclerotic encephalopathy. The Vasonit tool recommends the use of the Vasonit solution for chronic or acute disorders in the cerebral blood supply according to the ischemic type (ischemic cerebral stroke), circulatory disorders in the eye (chronic, subacute or acute circulatory failure in the choroid or retina). The drug is prescribed for trophic changes in tissues as a result of violations of venous or arterial microcirculation (with frostbite, gangrene, trophic ulcers, varicose veins, postthrombophlebitic syndrome). Medication is also indicated for hearing disorders of vascular nature, complicated by deafness.

The duration of the drug and the dosing regimen are set individually.

The drug "Vazonit" instructions for use recommends the appointment of a pill twice a day (in the evenings and in the mornings). The drug is taken after a meal.

The drug "Vazonit" can provoke some undesirable consequences. Side effects should include dry mouth, diarrhea, vomiting, a feeling of overflow in the abdomen, an upset of appetite. Probable pain in the epigastrium, jaundice, hepatitis or cholecystitis. In rare cases, there may be an unpleasant aftertaste in the mouth, convulsions, anxiety, headache, scotoma, conjunctivitis. Adverse reactions include dizziness, earaches, sleep disorders, blurred vision.

Taking medication in elevated dosages leads to a decrease in blood pressure, violations in the rhythm of the heart, tachycardia, facial hyperemia, angina pectoris, "hot flashes", puffiness.

Also allergic manifestations are possible on the background of treatment. In particular, Quincke's edema may occur, rash, hives, itching, anaphylactic shock (rarely).

The drug "Vasonitis" instruction for use is not recommended for extensive bleeding, acute myocardial infarction, hemorrhagic stroke, porphyria. Do not prescribe medication to patients under the age of eighteen, with hemorrhages in the retina, hypersensitivity. Contraindicated drug "Vazonitis" pregnant. Breastfeeding should stop lactation during the period of taking the medicine.

Before using Vazonit, you should consult your doctor.