Means of "Diphenin". Instructions for use

The medicine "Diphenin", the price of which reaches 100 rubles, refers to anti-epileptic, anticonvulsant, antiarrhythmic drugs. The drug has a muscle relaxant activity, does not have a pronounced sedative effect. Anticonvulsant action is noted against a background of partial and generalized seizures. The drug "Diphenin" affects the passive and active transport of sodium and calcium ions through the subcellular and cellular envelopes of nerve cells. By reducing the intake in the neuron, the sodium level decreases. Under the influence of the medication, a change in the calcium-phospholipid interaction in the cell membrane is noted, the release of aspartate and glutamate (neurotransmitter acids) from nerve endings is slowed. Antiarrhythmic effect is caused by a decrease in adrenergic influences of the central type on the heart, stabilization of the membranes of cardiomyocytes against the background of their permeability for potassium ions. On the basis of oral administration, the drug is absorbed quickly. Achieving the highest concentration occurs within 3-15 hours. Connection with plasma proteins by 70-90%. The drug passes through the histamine barrier. There is a rapid and extensive distribution of organs and tissues. Drug is withdrawn with urine and bile. The active substance is phenytoin.

The medicine "Diphenin". Instructions for use. Indications

Specialists prescribe medication for neuralgia in the trigeminal nerve, ventricular arrhythmias (against the background of poisoning by cardiac glycosides including). The indications include prevention of postneurosurgical and post-traumatic epilepsy, extensive convulsive seizures.

Means of "Diphenin". Instructions for use. Dosage

The medication is recommended after or during meals (to prevent irritation of the gastric mucosa). Dose to adults - 1/2 or 1 tablet per day 2-3 times. A day is allowed to take no more than 8 pieces. Children under five years of age, the drug "Diphenin" instruction for use recommends 0.25 tablets twice, from five to eight years - 3-4 times a day. From the age of eight, appoint half or a whole tablet 2 times a day. Children are recommended to take a joint medication with vitamins K and D.

Means of "Diphenin". Instructions for use. Side effects

On the basis of taking this medication, small changes in connective tissue (coarsening in facial features), vomiting, nausea, fever, tremor may occur. The medicine can provoke stimulation, dizziness, osteopathy, dyspeptic manifestations, flushing of the gums. To negative consequences should also be attributed to hypocalcemia. In case of appearance of severe reactions, it is necessary to lower the dosage or to cancel the medicine.

Contraindications

The drug "Diphenin" is not recommended for use in cases of porphyria, hypersensitivity, heart failure, kidney / liver function disorders. The expediency of prescribing during the prenatal period and during lactation is established by a specialist.