"Grandaxin": instruction, analogues. "Grandaxin" or "Afobazol" - what is better?

The drug "Grandaxin" refers to tranquilizers, which have a pronounced psycho-vegetative effect. The medicine is widely claimed in medical practice, as it can have a beneficial effect in the fight against depression, oppressed mental states. Similar effect has its analogs. "Grandaxin" is easily replaced with another drug. But is it safe?

Pharmacological effects

The drug is a tranquilizer. It refers to a group of benzodiazepine derivatives. Like its analogs, "Grandaxin" has an anxiolytic effect on the body. This effect is not accompanied by myorelaxing, sedative, anticonvulsant action.

This remedy is an excellent psycho-vegetative regulator, which relieves the patient from various forms of disorders. He has a moderate stimulating activity.

The lack of a muscle relaxant effect allows doctors to prescribe a sedative "Grandaxin" to patients suffering from myasthenia and myopathy.

In addition, the drug does not actually provoke mental or physical dependence in patients. It does not have withdrawal syndrome.

Structure of the medicine

The drug is available in tablet form. The pellet is round and flat, white in color (sometimes it may be slightly grayish).

The active substance of this drug is tofisopam. In addition to it, the medicine has a number of auxiliary components:

• Stearic acid;
• gelatin;
• potato starch;
• Microcrystalline cellulose;
• Magnesium stearate;
• talc;
• Lactose monohydrate.

Indications for use

The medicine is in great demand with neurosis-like conditions, neuroses. The instruction gives the following for the preparation "Grandaxin" indications for the appointment:

1. Reactive depression, accompanied by mildly psychopathological symptoms.
2. PMS, climacteric syndrome.
3. Neuroses and similar conditions.
4. Cardialgia.
5. Disorder of mental adaptation.
6. Alcohol withdrawal syndrome.
7. Myopathy, myasthenia gravis, neurogenic muscular atrophy and some other conditions, accompanied by neurotic symptoms (for the treatment of patients with anxiolytics, which have marked miorelaksiruyuschimi properties are contraindicated).

It has a favorable effect on the human body "Grandaxin". The medicine can eliminate unpleasant symptoms, which often accompanies neuroses:

• Apathy;
• Emotional stress;
• Anxiety (moderately pronounced);
• Obsessive-compulsive states;
• Vegetative disorders;
• A decrease in activity.

Dosage of the medicine

The reception of "Grandaxin" is prescribed exclusively by the doctor individually for each patient. After all, it is extremely important to take into account not only the pathology of the patient, but also his general condition.

Instructions for taking the medicine give the following recommendations:

1. Adults are prescribed 1-2 pills from 1 to 3 times a day.
2. If the drug is used irregularly, it is allowed to take 1-2 tablets.
3. The daily maximum dose can reach 300 mg. This is equivalent to 6 tablets.
4. Elderly people and patients suffering from kidney failure should reduce the dosage by 2 times.

Contraindications to admission

For some people, this tool, due to individual characteristics or pathologies, may not be suitable. Producers argue that the drug is contraindicated in the following phenomena:

• Respiratory insufficiency in the stage of decompensation;
• Lactation period;
• Hypersensitivity to the components of the drug;
• When the patient uses drugs "Cyclosporine", "Tacrolimus", "Sirolimus";
• In the first trimester of pregnancy;
• At a condition of the patient which is accompanied by the expressed aggressiveness, deep depression, a psychomotor excitation;
• A syndrome of a stop in a dream of breath;
• Deficiency of lactase;
• Intolerance to galactose;
• Malabsorption syndrome.

With increased caution, the doctor may prescribe medication to patients suffering from such diseases:

• epilepsy;
• Respiratory failure (acute);
• Angle-closure glaucoma;
• Organic brain damage.

Possible side effects

The drug "Grandaxin" can cause the patient to develop unwanted manifestations. As a rule, such reactions are observed in the elderly or patients suffering from impaired renal function, liver. It is noticed that side effects can also appear in people who are characterized by a delay in mental development. If such unpleasant reactions occur, the doctor will pick up no less effective analogues.

"Grandaxin" can cause the following side effects:

1. Flatulence, constipation, nausea, a feeling of dry mouth, decreased appetite, sometimes even cholestatic jaundice.
2. Stress in the muscles, pain in them.
3. Allergic reactions - itchy skin, exanthema.
4. Disturbed sleep, headache, psychomotor agitation, confusion, excessive irritability.
5. Intense breathing.

Important instructions

An excellent tranquilizer, able to relieve the patient of unpleasant symptoms, is the drug Grandaxin. The doctors' reviews fully confirm its effectiveness. However, at the same time, doctors recommend extremely careful use of this drug. Since along with the contraindications and side effects described above, a number of other features should be considered.

So, the medicine "Grandaxin" can strengthen the effect on the body of the following means:

• Antidepressants;
• Means of general anesthesia;
• Sedatives;
• Hypnotic drugs;
• Analgesics;
• Blockers of histamine H1 receptors;
• Antipsychotic medications.

Antiepileptic drugs, ethanol, nicotine, barbiturates can enhance the metabolism of the active substance of the drug "Grandaxin". Thus, the concentration of the drug in the blood decreases, and its effect on the body is weakened. In people with epilepsy, this medication can increase convulsive readiness.

In addition, the drug is not recommended at all in the case of chronic psychosis, phobias. Because the drug can trigger an increased risk of aggressive behavior in the patient and suicide attempts. That's why doctors never prescribe Grandaxin tablets for depression accompanied by anxiety, in the form of monotherapy.

The opinion of doctors

Most doctors use the drug "Grandaxin" in their practice. Reviews of doctors based on observations of patients, confirm the beneficial effect on the body.

In addition, the great advantage of this drug, according to doctors, is the amazing ability of the drug to not cause dependence and muscle relaxant action.

The remedy perfectly removes emotional tension, anxiety, apathy. And in modern life, overcrowded with stress, this is quite relevant. In addition, the drug helps women cope with PMS, menopause. In this case, it can be combined with hormone therapy.

Patient's opinion

Patients who take this medication are positive about it. After all, the remedy really does manage to cope with many unpleasant symptoms. It returns to the patient a lost sense of calm, normalizes well-being, relieves panic attacks. It is effective enough to help the medicine with VSD and osteochondrosis.

At the same time, the search for effective analogues of the drug "Grandaxin" (the price of which is palpable for the budget), because of the cost of the medicine, often begins.

There are very few negative opinions about the drug. And mostly they indicate the occurrence of side effects.

Cost of medicine

This is an important question that interests patients who are prescribed Grandaxin tablets. The price of the medicine, of course, may vary slightly. Therefore, we give the average data:

• Tablets (50 mg) № 60 - 610 rubles;
• Pills (50 mg) No. 20 - 301 rubles.

The main analogues

If necessary, replace the original remedy only with the doctor. If we talk about effective analogues, "Grandaxin" can be replaced by one of several drugs.

Among them:

• "Gidazepam";
• "Apaurin";
• Alprazolam;
• "Tazepam";
• Relanium;
• "Diamidazepam";
• Afobazol;
• "Nozepam";
• "Nerol";
• Seduxen;
• Relanium;
• Zolomaks;
• "Alzolam";
• "Phenazepam";
• "Chlosepide";
• Rudotel.

It is not possible to consider all the substitutes for the drug Grandaxin. Analogues, the price of some of them will be presented below, should appoint, do not forget about it, only the doctor.

"Grandaxin" or "Afobazol"?

Very often the original tool is replaced with this analogue. There is a fair question: "Which is better -" Afobazol "or" Grandaxin "?". There is no single answer.

Both drugs are tranquilizers synthesized on the basis of benzodiazepine. Their indications for use are almost identical. These drugs have a fairly similar effect. In addition, both the first and second medicine have proven themselves.

However, they also have differences. Both patients and doctors, analyzing what is better - "Afobazol" or "Grandaxin", notice that the first remedy has fewer side effects. In addition, it has not so many contraindications.

It would seem that the conclusion suggests itself. However, there is one more important nuance. This is the price of the drug Afobazol - 314 rubles. The cost of the drug is practically no different from the tablets "Grandaxin".

An effective analogue is the drug "Fenibut"

This remedy is a potent sedative. This is a highly effective sedative. It helps patients to cope with anxiety before surgery or other, equally responsible, activities.

The drug "Fenibut" is characterized by a rather unpleasant side effect - it is drowsiness. If you compare it with the tablets "Grandaxin", which have a stimulating effect, then its effect on the body is largely opposite.

Thus, the drug "Fenibut" is in demand with nervous excitability, which is accompanied by insomnia. In addition, it should be borne in mind that apathy does not apply the drug.

The cost of the drug depends largely on the manufacturer. In addition, it plays a role in which pharmacy will be purchased this tool. On average, for packing No. 20 you will have to pay 185 rubles.

Conclusion

Before you look for the drug "Grandaxin" analogue, be sure to replace it with a really effective and safe means. Since the original medicine is very advantageous among other tranquilizers. After all, it has a number of advantages.