'Lizinopril': instructions for use, pharmacology, contraindications

Cardiovascular diseases are the most dangerous and common ailments in modern society. Patients who have a number of problems with the heart, pressure and blood vessels are familiar with such a drug as lisinopril. The instructions for use attached to each medicine package contain information that the product is classified as an antihypertensive drug. However, the scientific name of the class of substance will not tell the average person, so let us turn to its properties.

Preparation "Lizinopril" - description of pharmacological properties

The effect of the drug is based on its ability to dilate blood vessels, as well as reduce the load on the heart muscle - the myocardium. In addition, tablets "Lizinopril" have natriuretic and cardioprotective effect on the body. Produce the drug in the form of tablets, which must be washed down with water. Their action begins in an hour, and by six o'clock the active substance has reached the limiting concentration. The influence is maintained during the day. To achieve a sustained antihypertensive effect, lisinopril is given a course of several weeks. Receiving tablets requires constant monitoring of the patient's condition.

Side effects and contraindications

Among the conditions under which the drug "Lizinopril" is prohibited, the instructions for use call pregnancy and the period of breastfeeding. In addition, the drug is contraindicated in kidney disease, hypersensitivity to the components of tablets, as well as children.

Side effects can be divided into three groups:

• Frequent manifestations (migraine, nausea, dizziness, dryness of the oral mucosa, weakness and dry cough);
• Middle frequency (diarrhea, abdominal pain, mental fatigue, tachycardia, rash, hypotension);
• Rare (impaired hematopoietic function, impotence, confusion, liver, kidney dysfunction, mood swings, hyperkalemia, Quincke's edema, as an allergic reaction to "lisinopril").

Instructions for use also describe such isolated manifestations of side effects as fever, weight loss, pulmonary hemorrhage and a number of other dangerous disorders.

Method of administration and dosage

Dosage is determined on an individual basis, based on body weight, age, as well as the work of the kidneys, liver and other organs, as well as the presence of a reaction to the drug "Lizinopril". Instructions for use include an indication of the need for a one-time intake of a daily dose, as determined by the doctor. There are three dosages: initial, medium or, as it is called, supporting and maximal.

The initial dosage is not more than 5 mg, and in the presence of indications, the daily norm is reduced to 2.5 mg.

The average dosage of the drug varies from 5 mg, to 20 at a time.

The maximum dose for the patient is 80 mg per day. Its appointment is permissible in exceptional cases, only after an appropriate examination.

Lizinopril - a description of the analogues

Like any medical product, "Lizinopril" has its analogues. These include "Lizigamma", "Lizoril", "Irumed", "Diroton", as well as other drugs containing vasodilating substances of the same group and class as lisinopril.

Special Recommendations

Tablets "Lizinopril" should be taken with extreme caution in case of disruption of the internal organs. Especially this recommendation applies to patients with kidney and liver function problems. The drug in the process of its effect removes from the body a colossal amount of salt and liquid. Before taking and during it, you should constantly make up for the loss.

In a particularly dangerous situation , the drug is also possible for pregnant women. However, the patient or her relatives are informed in advance of the risk. Treatment is carried out only if there is a threat to the life of the future mother.