Application and recall: "Neo-Pentotran"

Local antibacterial and antifungal drugs, actively used in gynecological practice, is the drug Neo-pentotrans.

Pharmacological properties

Active components of the drug - miconazole nitrate and metronidazole - cause its antiprotozoal, antibacterial action. Metronidazole inhibits the reproduction of nucleic acids of microorganisms, which leads to the destruction of their DNA and death. Miconazole disrupts the synthesis of elements of the cell membranes of fungi, which causes their destruction.

The agent has activity against anaerobic bacteria, trichomonads, pathogenic fungi, including the candida, gargantella, anaerobic streptococci. As the review indicates, "Neo-pentotrans" effectively fights some gram-positive bacteria.

Form of issue and analogues

A remedy is made in the form of vaginal suppositories, which contain from 100 to 200 mg of miconazole nitrate, as well as from 500 to 750 mg of metronidazole. The analogue of Neo-Pentotran Forte-L, in addition to the listed substances, contains 100 mg of lidocoin. Preparations that accurately copy the formula "Neo-pentotrana", no. The closest thing is the "Clion-D 100", which contains the same active components, but in other volumes.

Indications for use

Suppositories are prescribed for topical treatment of vaginal mixed infections, bacterial vaginosis. The drug is used for vaginal candidiasis, trichomonas vulvovaginitis.

Contraindications

As the review shows, "Neo-pentotrans" can not be used for severe abnormalities in the liver, porphyria, diseases of the nervous system, violations of hemopoiesis. Candles are not prescribed for hypersensitivity to active elements, in early pregnancy, for children and adolescents under 14 years. In the 2nd and 3rd trimesters the drug is used strictly according to indications. During lactation, if necessary, treatment should stop breastfeeding the baby.

Candles «Neo-pentotrans»: instruction, price

The medication is administered once a day in the evening. The course of treatment is a week. With relapsing vaginitis, the remedy should be used twice - in the morning and in the evening. Therapy is carried out for two weeks. With more prolonged use, as the review indicates, "Neo-pentotrans" can cause signs of an overdose. These symptoms are manifested by pain in the epigastrium, stomatitis, nausea, metallic taste in the mouth, itching. To buy candles "Neo-pentotrans", the price of which is 678 rubles, you can in the pharmacy without a prescription.

Side effects

The drug can provoke negative reactions of the body, which are similar to signs of an overdose. As evidenced by the review, "Neo-pentotrans" can cause itching, burning or irritation of the vaginal mucosa. In addition, dry mouth, abdominal pain, loss of appetite, diarrhea, metallic taste are observed. These symptoms pass after the end of therapy. In rare cases, from the side of the nervous system, there are psychoemotional disorders, headache, ataxia.