A shot from the allergy "Diprospan": application and feedback

How correctly to do an injection from an allergy "Diprospan"? The answer to this question is presented in the article. It contains information about what the patients say about the medicine, whether it has side effects, contraindications, etc.

Composition, description and packaging

A shot from the allergy "Diprospan" can be purchased at any pharmacy. The drug is available as a slightly viscous, clear and colorless suspension (can be slightly colored in yellow), which is used for injection.

The medication contains easily suspended elements of white or almost white color. It is free of foreign impurities, and when shaken it forms a stable, uniform liquid.

What composition has a shot from the "Diprospan" allergy? The active substances of the drug are betamethasone sodium phosphate and betamethasone dipropionate. It also includes distilled water, sodium hydrogen phosphate dihydrate, hydrochloric acid, sodium chloride, macrogol, disodium edetate, sodium carmellose, polysorbate 80, propyl parahydroxybenzoate, benzyl alcohol and methyl parahydroxybenzoate.

In what packaging can I get a shot from the allergy "Diprospan"? Patients' reviews say that such a drug goes on sale in glass ampoules, which are placed in packs of cardboard. Also, the medicine can be purchased in disposable syringes made of colorless glass (2 sterile needles are included). The syringes are placed in plastic containers, which are in cardboard packages.

Pharmacological properties

What are the properties of injections from the allergy "Diprospan"? The instruction attached to the drug states that this drug is a glucocorticoid. It has an insignificant mineralocorticoid and high glucocorticoid activity. The drug has an immunosuppressive, anti-allergic and anti-inflammatory effect. It also has a pronounced effect on all kinds of metabolism.

Pharmacokinetic properties

How does the injection of the "Diprospan" allergy affect the human body? Experts say that betamethasone sodium phosphate dissolves very well. After intramuscular injection, the drug is quickly hydrolyzed and immediately absorbed. Such a suction rate provides a good therapeutic effect.

The drug is completely excreted within one day.

As for betamethasone dipropionate, it is absorbed slowly (from the depot). The substance is metabolized gradually. This fact causes a prolonged exposure to the drug. This item is displayed for 10 days.

The bond of betamatezone with plasma proteins is approximately 62%. His metabolism in the liver is carried out with the formation of inactive metabolites. The drug is excreted mainly by the kidneys.

Indications for use

What is the purpose of the drug "Diprospan"? The injections in the joint (reviewed later) and other parts of the body are used to treat diseases and conditions in which glucocorticoids can achieve the maximum therapeutic effect. We should not forget that with some deviations therapy with this remedy is additional, and not the main one.

So what is the purpose of the injection for the allergy "Diprospan"? This drug is used when:

• Diseases of soft tissues, bone and muscle systems;
• Allergic reactions;
• Dermatological diseases;
• Systemic diseases of connective tissue;
• Hemoblastoses;
• Secondary or primary insufficiency of the adrenal cortex;
• Other diseases and pathological conditions that require therapy with systemic GCS.

Contraindications for use

Before you do the injection of "Diprospana", you should carefully study the instructions. It states that this drug can not be used in the following cases:

• With systemic mycoses;
• For subcutaneous and intravenous administration;
• For introduction into infected surfaces;
• For introduction into the intervertebral space;
• For intraarticular administration (with unstable joint or infectious arthritis);
• In children under three years of age (due to the presence of alcohol in the formulation);
• With increased sensitivity to drug substances;
• With increased sensitivity to other glucocorticoids.

Careful use of the drug

In what cases with special care is the medicine "Diprospan" prescribed? Pricks in the joint (reviews about this drug are ambiguous) and other parts of the body should be carried out under the strict supervision of a doctor when:

• Parasitic and infectious diseases of a bacterial, fungal or viral nature;
• Immunodeficiency states;
• Diseases of the digestive tract;
• Pathologies of the heart and blood vessels;
• Endocrine diseases;
• Severe renal or hepatic (chronic) failure;
• Thrombocytopenic purpura;
• Hypoalbuminemia and conditions that predispose to its occurrence;
• Obesity, systemic osteoporosis, eye diseases caused by herpes, lactation, myasthenia gravis, polio, acute psychosis, open and closed angle glaucoma, pregnancy;
• In the post-vaccination period.

It should also be noted that for intra-articular administration, this drug is administered cautiously in the general severe condition of the patient and the ineffectiveness of the action of the two previous injections.

The drug "Diprospan": the instruction

The injections, which can be seen in this article, are used for intramuscular, periarticular, intraarticular, intradermal, intra-abdominal, intralesional and interstitial administration.

Insignificant sizes of active substances of the preparation allow using needles of the minimum diameter. It should immediately be noted that the medication is not intended for intravenous and subcutaneous administration.

Injections must be carried out with strict adherence to all asepsis rules.

The method of administration of the preparation and its dosage regimen are established individually, depending on the severity of the disease, the indications and the patient's reaction.

Typically, the initial dosage of the drug is 1-2 ml. Repeated administration is carried out as needed.

Intramuscular injection is done deeply, choosing large muscles and avoiding other tissues.

Let's say an injection in the heel. "Diprospan" in this case, as well as with intra-articular injection, is used in a dose of 0.5-2 ml. This amount is enough to relieve the pain and remove the limited mobility of the joints.

With dermatological diseases, intradermal administration of the drug is quite effective.

After achieving a therapeutic effect, the physician must choose a maintenance dosage by gradually reducing the initial dose.

If there is a threat of a stressful situation that is not related to the disease, an increase in the amount of the drug may be required.

At the end of long-term treatment or use of the drug in high doses, the patient's condition should be monitored for at least a year.

The drug "Diprospan" (injections): side effects

This drug causes a rather large number of side effects:

• Hypernatremia, fluid retention in tissues, lipomatosis, increased release of potassium, increased excretion of calcium, weight gain, hypokalemic alkalosis.
• Increased blood pressure, heart failure (chronic).
• Muscular weakness, steroid myopathy, loss of muscle mass, osteoporosis, joint instability, compression fracture of the spine, ruptures of the tendons.
• Erosive or ulcerative lesions of the digestive tract with possible bleeding or perforation, flatulence, pancreatitis, hiccough.
• Violation of wound healing, petechiae, thinning of the skin and atrophy, ecchymosis, dermatitis, excessive sweating, striae, steroid acne, a tendency to develop candidiasis and pyoderma.
• Convulsions, personality disorders, increased intracranial pressure, dizziness, increased irritability, headache, depression, euphoria, insomnia and mood changes.
• Violations in the menstrual cycle, diabetes, delayed sexual development and growth in children.
• Subcapsular cataract posterior, blindness, increased intraocular pressure, exophthalmos and glaucoma.
• Anaphylactic reactions, angioedema, shock, arterial hypotension.
• Rush of blood to the face, neurogenic arthropathy.
• Skin and subcutaneous atrophy, hyper- or hypopigmentation, aseptic abscesses.

Patient Reviews

Many patients note that the drug "Diprospan" is highly effective in the treatment of joint, dermatological and allergic diseases. However, most people complain that the injections with the use of this remedy are extremely painful. Moreover, after several injections, side reactions often occur. This fact makes the subsequent treatment impossible, which forces the patients to return to the doctor again and purchase new medications. Given that one ampoule of the drug "Diprospan" costs about 200 rubles, such a refusal of further therapy noticeably beats on the wallet.