17 oxyprogesterone in women: basic indices and transcript

17 Hydroxyprogesterone is a hormone that is present in the body in humans. He plays an extremely important role. This component is especially important for those who are being treated for infertility or simply planning a pregnancy. That's why you should pay attention to this hormone. What is its concentration is the norm? What if the hormone is raised or lowered? Why can there be violations? All about this component will be described later. In fact, it's not difficult to understand why 17-OH is so important. And to pass the analysis on this hormone is even easier than it seems.

Description

First, you need to understand what substance is 17 hydroxyprogesterone. What is this in general? This hormone is sometimes called "intermediate". It plays an important role in the formation of a variety of substances in the body. For example, progesterone. It is an intermediate steroid. It is produced by the adrenal cortex.

In addition to progesterone, promotes the formation of estrogen and androgen. There are both men and women. But for girls 17, hydroxyprogesterone plays a more important role. Important for conception and pregnancy in general. Therefore, it is important to be able to determine the amount of a given substance in the body in humans. For normal conception, oxyprogesterone should be in sufficient quantity for both men and women.

How is the analysis done?

Before studying the established norms of the hormone in the body, it is necessary to understand how the analysis is handed over to it. Especially when it comes to women. The thing is that the beautiful half of mankind has a menstrual cycle. Some tests can not be taken at monthly intervals.

But 17 oxyprogesterone does not have such limitations. The analysis for this hormone is given in the form of venous blood. The fence is produced mainly in the morning on an empty stomach. Accordingly, men and women can donate blood to the concentration of oxyprogesterone at any time. It is recommended to refrain from the process during menstruation. This is not a direct contraindication. Just so you can avoid excessive error in the results.

Increase

Now you can learn about the reasons for raising and lowering the hormone. Only then it is necessary to look at normal indicators in this or that case. 17 Hydroxyprogesterone is often able to indicate serious diseases. Especially when it comes to metabolic disorders. After all, the studied hormone is involved in the breakdown of glucose, proteins, fats.

17 Is hydroxyprogesterone elevated? It does not matter who has a girl or boyfriend. Why this can happen? There are quite a few reasons. Normally, this hormone will be contained in certain sizes. An increase in its concentration in a person's blood can indicate:

1. Dysfunction of the adrenal cortex.
2. Polycystic ovary.
3. Tumor in the ovaries or adrenal glands.
4. Hyperprolactinemia.
5. Infertility.
6. Syndrome Itenko-Cushing.
7. Presence of a cyst of a yellow body.
8. Pathologies of the placenta.
9. Hypothalamic syndromes.

On this list of diseases does not end. But if the hormone is elevated - this is a sign of certain violations. True, not in all cases. That's why you often have to monitor the hormone content called 17 oxyprogesterone in women in the dynamics.

When the increase is the norm

The thing is that the female body is a complex mechanism that behaves differently than a man during life. And so the girls should not panic if the hormone indicated has risen sharply. Under certain circumstances, as already said, this is quite normal phenomenon.

At which ones? 17 Is hydroxyprogesterone elevated? In women, the increase in the concentration of this hormone is observed when pregnancy occurs. Unfortunately, it is impossible to say exactly by oxyprogesterone, whether the conception has occurred or not. Have to donate blood to HCG. But when planning a pregnancy, it is likely that the hormone will rise dramatically when the couple has succeeded.

Also, 17 alpha hydroxyprogesterone will be elevated during menstruation. Not always, but it happens. Why does the hormone start to be produced by the adrenal glands? This behavior is determined by the individuality of the menstrual cycle in women. In other words, someone has oxyprogesterone will rise sharply during periods of menstruation, someone - no. It is because of this that we sometimes have to observe changes in the hormonal background in dynamics. So it will be possible to understand whether there is a real disease in the body of the girl, or the increase in the hormone is associated with the individual feature of menstruation.

Decrease in the norm

In general, in women, 17 hydroxyprogesterone is in a small concentration initially. Under what conditions the hormone begins to be produced in large quantities, it is understandable. And what if the decrease in oxyprogesterone is observed? Why is this happening? Should I panic?

Not really. But, as practice shows, quite often there is a rise in this hormone. Its decrease may indicate adrenal gland diseases, for example. Both congenital and acquired. In some cases, 17 hydroxyprogesterone is contained in small amounts if the body has a too short luteal phase. Also, a low level of hormone indicates infertility. In fact, serious deviations of oxyprogesterone from the norm are a common cause of problems with conception.

What is dangerous to lower the hormone?

Why is it necessary to fear reduction of 17 oxyprogesterone when planning pregnancy? The thing is that this substance, as has already been said, increases with an interesting situation. In fact, a sharp drop in it is a pathology. Low concentration of the substance leads to the fact that the fertilized egg can not attach to the uterus. This phenomenon or becomes the cause of ectopic pregnancy, or leads to an unsuccessful conception.

In the early stages of pregnancy, a lower level of a hormone called 17 oxyprogesterone can lead to miscarriages, abnormal placenta formation, fetal pathology. Fortunately, to raise or lower the level of the hormone is not so difficult.

Methods of increasing and lowering the hormone

So, to easily regulate the concentration of the substance in the body, it is usually necessary to take a variety of medications. By the way, if a person has been treated for a long time, then 17 hydroxyprogesterone rises. It's enough just to cancel pills and other drugs, as the level of the hormone drops to the expected rate.

In general, the increase is treated with a variety of hormonal drugs. Most often, a drug called "Dexamethasone" is prescribed. Take it carefully - you can overweight. Other hormonal drugs are prescribed only by the attending physician.

Elevate 17 oxyprogesterone can be either by improving nutrition, or by treating a particular disease. In some cases (most often this is the way doctors recommend), too, a variety of hormonal drugs are prescribed. In fact, if in time to identify abnormalities, then bring oxyprogesterone to the desired level is not so difficult. Problems can arise during pregnancy. Then treatment is reduced to folk methods. Or the doctor prescribes the least dangerous hormonal means for both raising the hormone in the blood, and for lowering it.

Normal values

And what indicators are considered normal? How much of a woman's blood contains a hormone called 17 oxyprogesterone? The norm for non-pregnant people depends on the age. Small increases or depressions are not dangerous. But in an ideal it is required to be guided by following values:

• The newly-born girls are 4.08-29.4 nmol / l.
• 2-3 months - 0,3-9,4 nmol / l.
• From 12 months to 14 years - 0.42-6.9.
• Adolescents from 15 years - 0,5-11,5 nmol / l.
• Women during the follicular phase - from 0.5 to 8.24 nmol / l.
• Women during the luteal phase - 1-11.5.
• Postmenopause - not less than 0.7 and not more than 5.9 nmol / l.
• Pregnancy - from 3,6 to 33,3 nmol / l.

Accordingly, such indicators indicate the absence of certain diseases. As already mentioned, 17 hydroxyprogesterone may deviate slightly from these standards with full health in women.