Uniothiol: instructions for use, reviews

Poisoning with heavy metals, low-quality alcohol and other substances should be treated immediately. Otherwise, it can lead to death.

Modern pharmaceutical companies produce a lot of detoxification products. They are necessary for the rapid removal of toxic compounds from the human body, significantly easing his condition.

The most popular anti-poisoning drug is Uniothiol. Instructions for use, doctors' comments on the effectiveness of this drug, we will consider below.

Description, composition, form of release of the medicament and its packaging,

In what form can you find the drug "Unitiol" in the pharmacy? Instructions for use (in tablets this medication is not produced) indicates that the said agent is issued as a clear solution, which is intended for subcutaneous or intramuscular administration. It has a faint smell of hydrogen sulfide, as well as a light pink color (can be colorless).

What components are included in the product Uniothiol? The instruction for use states that the active ingredient of this agent is sodium dimercaptopropanesulfonate monohydrate. The medicament also includes auxiliary compounds in the form of sulfuric acid, disodium edetate (Trilon B), and water for injection.

On sale this medicine comes in ampoules of glass of 5 ml. They are packed in contour cells, which are placed in bundles of paper.

Pharmacodynamic properties

How does Uniothiol medication work? Instruction for use reports that it is a detoxification agent that quickly eliminates the deficiency of sulfhydryl groups. By its way of acting, this drug is very close to complexions.

According to specialists, sulfhydryl groups are able to react with thiol poisons in the blood and tissues, forming harmless complexes evacuated together with urine.

The blocking of poisons helps to restore the work of all enzyme systems in cells that have been hit by toxic substances. This drug is used as an antidote for arsenic poisoning, heavy metals and their compounds.

In people with polyneuropathy of diabetic genesis and with secondary amyloidosis this medication weakens the pain sensations, improves the indices of the NS, and also regulates the permeability of capillaries.

Kinetic features

What kinetic properties are inherent in the medicine "Unitiol"? Instructions for use asserts that, after subcutaneous or intramuscular injection, the drug molecules actively penetrate the bloodstream. The greatest concentration of the drug is recorded after about 40 minutes (after the / m administration).

Half-life of the drug is two hours. The drug is excreted together with urine in the form of incomplete oxidation products.

Solution readings

At what indications can the medicine "Unitiol" be prescribed to a patient? Instructions for use (injections should only be carried out by an experienced medical professional) indicates that this remedy is used for:

• Intoxications with bismuth, arsenic, chromium, mercury or cardiac glycosides;
• Alcoholism of a chronic nature and alcoholic delirium as part of combined treatment;
• Hepatocerebral dystrophy (Wilson-Konovalov syndrome).

Contraindications

Are there any contraindications to the medicine "Unitiol"? The instruction for use states that the agent in question can not be assigned when:

• Sensitization to the drug;
• Hepatic insufficiency;
• At a minor age;
• Pregnancy;
• Arterial hypertension;
• Breastfeeding.

The drug "Unitiol": instructions for use

In ampoules this product can be purchased at any pharmacy. According to the instructions, this drug should be administered subcutaneously or intramuscularly.

In the treatment of arsenic intoxication, the medication is used at the rate of 50 mg of the active ingredient per 10 kg of the weight of the affected (ie 250-500 mg). In the first day of treatment, this dosage should be administered up to 4 times, in the second - up to 3 times, and in the subsequent - once.

When treating poisoning with salts of mercury, the drug is used as described above for seven days or until the symptoms of intoxication disappear completely.

In the treatment of poisonings with cardiac glycosides on the first and second days, the drug is administered at the rate of 50 mg of the active ingredient per 10 kg of the patient's weight (that is, 250-500 mg) four times a day, and on the next day - twice or until the symptoms of cardiotoxic action disappear.

In the treatment of hepatocerebral dystrophy, medication is administered intramuscularly at 5-10 ml in a standard concentration every day or two days. The duration of therapy is 26-30 injections. If required, the course is repeated after 4 months.

For the treatment of alcoholism of a chronic nature, the drug is used in an amount of 4-5 ml in standard concentration up to 3 times a week.

In the treatment of delirium, medication is administered once (5 ml in standard concentration)

Adverse events

With the use of the drug in question, adverse reactions are extremely rare. In some cases, the patient develops tachycardia, dizziness, nausea and pale skin. In addition to the above, there may be reactions of an allergic nature.

Overdose and drug interaction

When an overdose in the patient appears shortness of breath, hyperkinesia, blocking, cramps and lethargy. In this case, symptomatic therapy is performed.

This drug is pharmacologically incompatible with drugs that include heavy metals, as well as with alkalis. He is also not appointed with "Acizol".

Reviews

Consumer feedback on the drug in question is extremely rare. This is connected with the fact that this medication is used mainly in stationary practice.

As for experienced doctors, they respond to the solution of Uniothiol as a very effective and effective remedy, which evacuates toxins, including alcohol poisoning.