The preparation "Stugeron" instructions for use.

Preparation "Stugeron": Form of release, packaging and composition

Tablets of white color, flat, round, with one facet, practically do not have a smell, on one side there is an inscription "STUGERON", twenty-five milligrams of active substance - cinnarizine, on blisters for twenty five and fifty tablets. The composition includes, in addition to cinnarizine, also auxiliary substances: colloidal silicon dioxide, potato starch, magnesium stearate, talcum, povidone, corn starch, lactose monohydrate.

Pharmacological effects of the drug "Stugeron", the instruction for use describes as follows.

It reduces the flow of calcium ions into cells, the tone of smooth muscle fibers in the walls of arterioles, contributes to the enhancement of the relaxing vessels of the effect of carbon dioxide and much more. Since the drug "Stugeron" has an effect directly on the smooth muscle of the vessels, it can reduce their response to the effects of nutrients (adrenaline, angiotensin, dopamine, vasopressin). Has a vasodilating effect (especially concerning the vessels of the brain), but it does not have a serious effect on blood pressure. It shows antihistamine activity, affects the vestibular apparatus, reducing its excitability, and the sympathetic nervous system, reducing its tone. It also causes an increase in the elasticity of membranes in erythrocytes, their ability to deform, and reduces the viscosity of the blood. In addition, it increases the resistance of the muscles of the body to hypoxia.

Pharmacokinetics of the preparation "Stugeron" instructions for use describes this.

Resorption of the drug occurs in the intestine and stomach. The maximum concentration in the plasma after taking the drug inside is reached after one to three hours. Plasma proteins bind ninety-one percent of cinnarizine. It metabolizes the drug (through glucuronation) completely in the liver. The half-life period is four hours. Metabolites of cinnarizine are excreted by one third of the kidneys and two-thirds by the intestines.

The dosage of the preparation "Stugeron" is given in the instruction manual.

You need to take it in after eating. With cerebral circulatory disorders, twenty-five to fifty milligrams (one to two tablets) three times a day. With peripheral circulatory disorders, fifty to seventy-five milligrams (two to three tablets), three times a day. And in the case of vestibular disorders - twenty-five milligrams (one tablet), three times a day. In the case of road disease (kinetosis), the dosage for adults is twenty-five milligrams, half an hour before the road (if necessary, you still need to take the same after six hours), Stugeron's children in such cases are given half the dose recommended For adults. In the case of the presence of hypersensitivity to one of the components of the preparation "Stugeron", the instructions for use recommend starting treatment with half the dose, gradually increasing it. The course of treatment usually lasts from weeks to months. The maximum allowable daily dose of the drug "Stugeron" instruction for use gives in two hundred and twenty five milligrams or nine tablets.

In case of an overdose, the victim is washed with a stomach to clean water, and activated charcoal is given.

Do you prescribe Stugeron to children?

The responses in the network relate mainly to his appointment with perinatal encephalopathy, which arises from fetal hypoxia, as well as with perinatal CNS damage and the syndrome of neural-reflex excitability. There is a definite positive effect. According to the doctor's order, give him a quarter tablet twice a day after meals, ground in a spoon with a mixture for feeding or at the end of feeding. In the end - give a drink with the rest of the mixture or water.