The drug "Ceftriaxone": indications for use

The drug "Ceftriaxone" refers to the pharmacological group of cephalosporin antibiotics, has bactericidal and antibacterial properties. The medicine has a wide range of action, it destroys the biosynthesis of the mucopeptide of the cell walls of bacteria, inhibits transpeptidase.

The preparation is made in the form of white or yellowish-orange powder for the preparation of injections in 0.5, 1 and 2 grams of vials. The substance is easily soluble in water, the color of the injection varies from yellow to amber depending on the shelf life.

The drug "Ceftriaxone": indications for use

The medication is prescribed for the therapy of infectious manifestations, which are caused by microorganisms sensitive to the antibiotic. The list of indications includes infections of the ENT organs, lower and upper respiratory tract, any forms of bronchitis, empyema of the pleura, abscess of the lungs.

Effective is the drug "Ceftriaxone" for pneumonia, infectious pathologies of soft tissues and skin infections, streptoderma. Antibiotics are used to treat the genitourinary system, pyelonephritis, pyelitis, prostatitis, cystitis, epididymitis, gynecological infections, uncomplicated forms of gonorrhea.

The medicine is used to destroy microorganisms that damage the organs of the abdominal cavity, gastrointestinal system, bile ducts.

It is worth using the drug "Ceftriaxone" for sinusitis, for the treatment of peritonitis, sepsis and bacterial septicemia, endocarditis and meningitis, osteomyelitis, syphilis, soft chancre and spirochetosis.

In some cases , injection solution is prescribed for the treatment of salmonellosis, typhoid fever, as well as for the prevention of purulent, septic complications after operations.

"Ceftriaxone" preparation: indications for use and method of application

Antibiotic is administered intravenously and intramuscularly. Only fresh solutions can be used for treatment.

When administered intramuscularly, the powder is dissolved in sterile water for injection. To use half and 1 gram of the drug, take 2 and 3.5 ml of water, respectively. Injections are inserted deep enough into the outer upper part of the gluteus muscle (no more than 1 g per site). To eliminate soreness, one-percent solution of the drug "Lidocaine" can be used.

With intravenous treatment, the antibiotic is dissolved in sterile water for injection in a ratio of 0.5 g to 5 ml. Enter the solution into the vein slowly for three to four minutes.

The drug "Ceftriaxone": indications for use and side effects

In general, the antibiotic is well tolerated. However, in some cases, vomiting, nausea, diarrhea, cholestatic jaundice, hepatitis, pseudomembranous colitis may occur . When using the drug, allergies are possible, manifested in the form of pruritus and rash, eosinophilia. From the side of the urinary system, a reaction is possible in the form of interstitial nephritis, and on the part of the circulatory system, hypoprothrombinemia can be observed.

The drug "Ceftriaxone": indications for use, contraindications and overdose

The agent is not prescribed for hypersensitivity to the drug, penicillin and other cephalosporins. It is inadmissible to use the medication in the first trimester of pregnancy, with breastfeeding, with renal or hepatic insufficiency.

With long-term treatment with "Ceftriaxone" with the use of high doses, the blood picture can change (thrombocytopenia, hemolytic anemia, neutropenia, leukopenia). High excess plasma concentrations can not be reduced by peritoneal or hemodialysis, so treatment in such cases is symptomatic.