The medicine 'Metoclopramide'. Instructions for use

The drug "Metoclopramide" (tablets) is considered to be quite effective (according to reviews) means, which helps to reduce emetic pressure on the background of intestinal infections. The medication is shown to both adults and children. As a rule, the drug is transferred well enough.

The agent "Metoclopramide" instructions for use refers to antiemetic, prokinetic, anti-icic medicines.

The drug helps to stimulate the motor activity and normalize the motor function of the upper part in the digestive system, regulate the tone of the lower esophageal closure (sphincter) at rest. The medication increases the amplitude and tone of the contractions of the stomach (especially the antrum), relaxing the sphincter of the bulb of the duodenum and pylorus, enhances peristalsis and accelerates gastric emptying. When taking the drug "Metoclopramide" normalizes bile secretion (due to increased pressure in the bile duct and bladder), eliminates dyskinesia of the gallbladder, and reduces the spasm of the sphincter of Oddi.

As an antiemetic, the drug is effective for vomiting and nausea of a variety of origins. Such conditions can be associated with chemotherapy prevention of cancer, violation of diet, pregnancy ("vomiting of pregnant women"), traumatic brain injury, kidney and liver pathologies, side effects of drugs, anesthesia.

The medicine is used for hiccup of a different nature of origin, functional disorders in digestion, gastro-esophageal reflux disease, exacerbations of peptic ulcer.

The agent "Metoclopramide" instructions for use also characterizes as an effective medication for migraine (to prevent nausea, to stimulate the absorption of anti-migraine drugs for oral administration).

Use the drug and in preparation for diagnostic measures for the gastrointestinal tract.

It should be noted that the drug is ineffective in vomiting vestibular nature.

Characterizing the drug "Metoclopramide", the instruction for use indicates the presence of its properties to suppress the peripheral and central effects of apomorphine, to increase the production of prolactin, to provoke a transient increase in the level of aldosterone (probable short fluid retention). When taking medication, there is also an increase in sensitivity to acetylcholine.

Solution of the drug "Metoclopramide" (in ampoules) with intravenous administration begins to act after one to three minutes, after intramuscular injection - after ten to fifteen minutes. With oral intake (inside), the effect is noted after thirty to sixty minutes. The duration of the action is of the order of one or two hours.

Contraindications to the drug "Metoclopramide" instructions for use include stenosis of the pylorus, bleeding in the gastrointestinal tract, hypersensitivity, perforation of the intestinal or gastric wall. Do not prescribe medication for glaucoma, epilepsy (in connection with the probability of increasing frequency and severity of seizures), pheochromocytoma, Parkinson's disease and other extrapyramidal disorders . Not recommended drug "Metoclopramide" in the case of prolactin-dependent neoplasms, and also at the age of up to two years.

Dosing regimen

The drug "Metoclopramide" is prescribed orally three times a day for 5-10 milligrams before meals. Intravenous or intramuscular administration is recommended in an amount of 10 milligrams. Dosage for one dose should not be more than twenty milligrams, per day - sixty milligrams.

For children older than two years, the dose is set by the doctor according to age.

Before using the drug "Metoclopramide" you need a doctor's consultation.