The drug "Nice" (tablets). Instructions for use

Naise is produced by Indian pharmacists, it became popular in our country due to its numerous positive sides, and the main one is the ability to quickly reduce or completely suppress the pain syndrome of a variety of origin. The drug "Nice" (tablets) instructions for use refers to anti-inflammatory non-steroidal agents that are capable of showing analgesic, antipyretic and anti-inflammatory effects.

The pharmacokinetics of this drug in the instructions are described as follows:

After ingestion, this medicine is well absorbed. Since in the blood it circulates in a condition associated with blood proteins, then in case of its use together with other medicines, nimesulide is able to displace them from the bonds with proteins and, accordingly, to increase the concentration of their free fractions in the blood. The fact of sharing with the food intake of the drug "NICE" (tablets) instructions for use describes as a factor that slows the absorption of the active substance, but in no way affects the extent of its absorption.

Indications for its use exist as follows: myalgia, the most diverse etiology of arthritis, arthralgia, various genesis of fever, algodismenorea, bursitis, head and tooth pains, tendonitis, post traumatic and postoperative pain, osteoarthrosis.

Contraindications for the drug "NICE" (tablets) instructions for use calls renal and hepatic insufficiency, increased sensitivity to the components of the drug (especially nimesulide), diseases of the digestive tract, internal bleeding (especially from the digestive tract), pregnancy, the period of breastfeeding. Also contraindication is the age of patients under twelve. With caution, the "Nice" (tablets) preparation recommends that patients with hypertension, diabetes mellitus type II, heart failure should be prescribed.

For the preparation "NICE" (tablets), the composition in the instruction is given as follows: the main active substance of nimesulide is one hundred milligrams, auxiliary substances.

The "Nice" tablets are taken orally twice a day, before meals, with a sufficient volume of liquid. If the patient suffers from the pathology of the digestive tract, the "Nice" (tablets) preparation is recommended for use after eating or at the end of its administration. The maximum allowable dose per day is four hundred milligrams.

For children over the age of twelve and a body weight exceeding forty kilograms, he is appointed based on this calculation: one and a half milligrams per kilogram of body weight. For this age and weight category, the maximum intake of the drug in a dose not exceeding five milligrams per kilogram per day is allowed.

For children aged more than twelve years, but with a body weight that does not reach forty kilograms, the "Nice" (tablets) preparation instruction instruction recommends using one hundred milligrams twice a day. The duration of treatment is ten days.

Side effects, which can provide medicine "Nice", the instruction to him lists the following:

On the part of the digestive tract, nausea, diarrhea, vomiting, heartburn may occur, in the liver - an increase in the activity of transaminases, toxic hepatitis, the mucosa of the digestive tract may also ulcerate. From the side of the nervous system, headaches and dizziness are sometimes noted. On the part of the circulatory system - the development of anemia, agranulocytosis, thrombocytopenia, leukopenia, an increase in the time interval necessary to stop bleeding, hematuria. Also, allergic reactions of varying intensity may develop, fluid retention in the body.