Ointment 'Lokoid'. Instructions

Ointment "Lokoid" belongs to the category of glucocorticosteroid preparations for local use. The active ingredient is hydrocortisone 17-butyrate. The drug has a sufficiently rapid anti-inflammatory, antipruritic and anti-edematous action.

Therapeutic dosages of the drug do not exert a depressing effect on the hypothalamic-pituitary-adrenal system. The use of the drug "Lokoid" in large quantities for a long time can contribute to an increase in the concentration of cortisol in the plasma.

After application, the drug begins to accumulate in the epidermis, especially in the granular layer. Systemic absorption of the drug is negligible.

Metabolism of the active substance occurs in the epidermis, and then in the liver.

Hydrocortisone and other decay products, as well as a small amount of unchanged active ingredient, are excreted by the kidneys and intestines.

Ointment "Lokoid" instruction recommends for psoriasis, eczema, dermatitis (seborrheic, atopic and contact, including).

It was found that hydrocortisone 17-butyrate penetrates through the placenta. Negative effects can be more pronounced when using the remedy in large areas. In this regard, the drug "Lokoid" during pregnancy is used with extreme caution (on the advice of a doctor and under strict control of it).

It is not established whether the active ingredient is able to penetrate into the milk. Thus, the expediency of using the drug during lactation is determined by the doctor.

Ointment "Lokoid" instruction does not allow for the appointment in viral, fungal, parasitic, bacterial skin infections. Contraindications include shingles, gram-negative folliculitis, chicken pox, streptoderma, herpes simplex, staphyloderma. Ointment "Lokoid" instruction does not recommend for syphilitic and tuberculous skin lesions, neoplastic changes in the cover (benign or malignant neoplasms). Do not prescribe medicine for perioral dermatitis, rosacea, acne. Ointment "Lokoid" instruction does not recommend applying to areas with damaged integrity of the cover (wounds or ulcers). Do not prescribe the remedy in the post-vaccination period.

The drug is used externally.

Ointment "Lokoid" is especially recommended in the presence of dryness, infiltration (accumulation of liquid) and lichenification (skin tightening).

Apply the medicine no more than three times a day. The agent is applied to the problem areas with a thin layer. With a decrease in the severity of manifestations, the frequency of use may be reduced to two to three times within a week.

Strengthen the penetration of the drug can be light massaging movements.

On dense psoriatic plaques on the knees, ulnar areas after ointment treatment, occlusive dressings are allowed.

The dosage of the drug per week is no more than thirty to sixty grams.

The "Lokoid" agent can cause local reactions in the form of irritation.

With prolonged use in areas of large area or the application of occlusion, the development of manifestations characteristic of the effects of systemic glucocorticosteroids is likely.

It is not recommended to apply the medicine to the periorbital zone, in connection with the likelihood of the occurrence of glaucoma. Regular penetration of ointment "Lokoid" in a conjunctiva provokes an increase in intraocular pressure.

It is not recommended to use the medicine on the scalp, as well as for acute inflammation on the skin.

About the drug "Lokoid" reviews are different. Some patients report a lack of results after the therapy. There is evidence that the drug has only a temporary effect, reducing the intensity of symptoms for the period of treatment. Some patients talk about the effectiveness of the medication.

Use of the drug "Lokoid" should be agreed with the doctor. Before using, it is recommended that you read the annotation.