"Reamberin": indications for use, reviews, instructions, analogues

Intoxication is a consequence of various causes. In medical practice, such scenarios often develop in the course of surgical interventions, and as a result of infectious organ / system damage. As a side effect of intoxication, in particular, it is possible and with complex therapy, that is, when long-term wellness measures are carried out on the basis of several potent pharmaceutical products. Alcohol-containing tinctures and balms, if used uncontrolled, are also capable of provoking poisonings of varying severity.

"Reamberin" (indications for use, doctors' comments on the expediency of prescribing this medication, as well as comments of experts on the drugs-synonyms, will be given below) is a desintoxicator, which has undergone laboratory and clinical studies and is made on the basis of succinic acid. The main task of the reagent is to stimulate natural intracellular processes aimed at stabilizing the energy balance and self-purification of the organism.

Information on the chemical composition

In the case of the drug "Reamberin" indications for use (reviews left by users, fully confirm the information contained in the instructions) are determined by the components of the solution. The role of the biochemical "contactor" is played by NN-methyl ammonium succinate sodium; Auxiliary functions are assigned to Cl-derivatives of potassium, magnesium and sodium, as well as specially prepared water. In recalculation for 1 ml of liquid, the share of the ingredients is expressed as follows: 15 mg, 0.3 mg, 0.12 mg, 6 mg, respectively.

The drug belongs to the group of injection reagents and is a clear, odorless solution.

The production form of production - glass bottles in volume of 100 ml, 200 ml and 400 ml and plastic capacities for 250 ml and 500 ml; In drugstore chains the product arrives in original cardboard packages.

More details about the mechanism of pharmacological action

The active component of the drug "Reamberin" - indications for use (reviews about the drug can be easily found on thematic forums) exclude the possibility of appointment in renal / hepatic pathologies - demonstrates its hepatoprotective, antioxidant and detoxification properties through direct intervention in the metabolic processes that occur in the body. What is most interesting: by his presence, he focuses the cells on "accelerated utilization" of not only glucose, but also fatty acids. At the same time, being a stabilizer of membrane membranes, NN-methylammonium sodium succinate possesses a diuretic effect.

Regular intravenous infusions do not entail the accumulation of the reagent - the components are well absorbed, after which they are transformed and completely consumed by the cells during the structural-energy substitutions.

Detecting lesions of hepatocytes, this ingredient initiates the regeneration of the hepatic tissue. This process is well traced by taking clinical blood samples (in the interval from one control point to another, the concentration of enzymes corresponding to cytolysis is markedly reduced). Similarly, the behavior of NN-methyl ammonium succinate sodium and with ischemic disorders. After infusion in the cardiac muscle, multi-stage reparative changes begin, the result of which is the "blockade" of degraded zones and the gradual "reincarnation" of cells.

Reamberin: indications for use

With allergies to the previously listed components of the solution (even when atypical reactions are unstable and poorly expressed), therapeutic measures based on this drug are not used. And this is the first thing that needs to be understood, because if the symptomatology of the disease meets the indications stated in the instructions, but the patient is found to be intolerant of the substances that make up the described pharmacological product, then instead of the healing effect, the injection may well lead to serious complications in the work of organs And systems.

Regarding the conditions of use in the official manual, the following information is provided:

• The reagent is expedient for prescribing both under hypoxic conditions provoked by various factors and for the purpose of achieving detoxification of the organism (including during the postoperative period, with significant blood loss, impairment of respiratory function, ischemic destruction, uncritical occlusion of vessels, poisoning with xenobiotic compounds, );
• The introduction of NN-methylamonium sodium succinate is justified if the patient has to undergo a complete therapeutic course aimed at eliminating cholestasis or hepatitis (regardless of etiology);
• The patient has a hemorrhagic shock, there is a polytrauma;
• Infectious intoxication is diagnosed.

Optimal daily dosage

"Reamberin" - indications for use (reviews about the solution among practitioners are mostly positive, but some experts focus on the inability to use this medication in cases of brain damage) were presented in the previous section of the article - prescribe intravenously, drip. The daily rate and the speed of infusion are calculated individually, based on the current situation and the episodes given in the anamnesis.

The manufacturer of the drug recommended to adhere to the following dosage:

• In normal conditions, adults from 400 ml to 800 ml of fluid are administered to adults (permissible norm is 2000 ml / day);
• In case of shock conditions, adults are placed with a dropper in such a way that within a minute, 1,0-1,5 ml of the solution enters the body (the same limit is 2000 ml);
• With progressive viral hepatitis - 200/400 ml (with mandatory daily monitoring of the concentration of cytolysis enzymes);
• Newborns and babies who have not yet turned a year are prescribed a daily volume of the reagent, based on body weight - from two to five milliliters of detoxifier for every thousand grams of the child's weight (infusion regimen: 1 procedure / 24 hours);
• For preterm there is a rule of "+1 ml to the established rate";
• For children over 12 months, another formula is applicable: 10 ml per 1 kg of body weight, but not more than 400 ml / day at a rate of 3-4 ml per minute (with a portion of the solution divided in half and injected at intervals of 7-10 hours).

Total length of the course:

• For patients of the age category "18+" - 7-11 days;
• For patients of younger group - 3-5 days.

Side effects

Cases of an atypical reaction of an organism, confirmed experimentally:

• The appearance of a stable metallic taste in the mouth;
• Skin rashes and hives;
• Sharp reddening of the trunk (lasts 5-10 minutes and usually occurs when the recommendations regarding the speed of infusion are not observed).

It should be understood that if using the "Reamberin" drug indications for use (reviews with psoriasis, and this form of skin inflammation affects about 3% of the world's population, are extremely positive, on average, after one week you can achieve remission) will be deliberately ignored, then The likelihood of developing side effects will increase manyfold.

Limitations and contraindications

As already noted, the reagent is not prescribed in the presence of individual hypersensitivity to the composition. In addition, the presence of NN-methylamonium sodium succinate in the patient's medication chart is extremely undesirable in case of craniocerebral trauma (when there is a suspicion of cerebral edema).

Among other things, the manufacturer warns against the ill-considered use of the solution in complex pathologies of filtering organs (primarily the liver and kidneys).

Special Instructions

Important nuances, which should be remembered, adapting the health course to the pharmacological properties of the drug "Reamberin":

• Indications for use (reviews similar, I must say, were not so flattering, so it is difficult to determine a direct competitor) lose their relevance if the requirements set out in other sections of the original instruction are not met when prescribing a therapeutic dose;
• Infusion is able to lower the concentration of glucose in the blood;
• It is impossible to exclude alkalization of urine.

Incompatibility with other compounds is a rare phenomenon, but possible.

Reamberin: indications for use in pregnancy and lactation

There were no large-scale studies in this direction. The decision to prescribe the reagent during fetal / breastfeeding remains with the attending physician (the dominant opinion is that there is no direct threat of infusion).

There are a lot of scenarios where an intentional departure from the rules for using the drug "Reamberin" is permissible.

Indications for use in psoriasis developing during pregnancy, in particular, are that the injection is absolutely justified, if the expected benefit from it significantly exceeds the potential risk.

Biochemical contact with other pharmaceutical products

Among other things, the manufacturer reports that the described drug is well combined with antimicrobial medicines and water-soluble vitamins. In addition, the "Reamberin" - indications for use (the instruction only outlines the framework of biochemical alliances - it is the specialized specialist who must calculate the interaction algorithm, but do not take into account particular cases, and this must always be remembered) - enhances the action of glucose and simultaneously acts as an antagonist of the group Barbiturates.

The most popular analogues: the point of view of independent experts

"Reamberin" (indications for use in hepatitis C, which are given in the official manual, make it clear that the total length of the course should not exceed 10 days, but some substitutes may be present in the patient's medication chart for 3-4 weeks, and this fact is the reason for the discussions Around the issue of the safety of the described detoxifier) is a fairly popular and effective antioxidant with cardio, nephro- and hepatoprotective properties.

Nevertheless, some experts advise periodically to "expand the horizon," because the pharmaceutical market is continuously developing. Among the samples worthy of attention, they are particularly distinguished:

• "Glucksyl."
• "Xylat".
• "Sorbilact".