HealthDiseases and Conditions

Hormone FSH, why is it elevated and lowered?

A lot of hormones are produced in the human body. Produce their endocrine glands. Homons affect virtually all processes occurring in the body. Violation of their balance can lead to serious pathologies.

One of them is infertility, which is often endocrine. Basically, the cause of this is the imbalance of sex hormones. And he leads to both female and male infertility.

Even if the amount of only one hormone is increased or decreased, this can be detrimental to fertility. And since all elements of the endocrine system are interrelated, this will eventually lead to a complete imbalance.

Follicle-stimulating hormone (FSH) is produced in the pituitary gland. Its release into the blood occurs in portions after a few hours. In the future, FSH hormone binds in men to Sertoli cells, in which the synthesis of androgen-binding protein is activated. This facilitates transportation to the epididymis of testosterone.

In women, FSH hormone binds to the receptor apparatus of ovarian cells. It stimulates the growth of follicles, preparing them for ovulation.

So, the FSH hormone performs the following functions in the body:

  • Promotes maturation and the formation of sex cells;
  • Affects the synthesis of estrogens (sex hormones of women);
  • Stimulation of the growth of the vas deferens;
  • Increase testosterone levels in the blood, ensure libido and maturation of spermatozoa;
  • Influence on the formation of the follicle, leads to ovulation.

Today, the level of this hormone can be determined in any modern laboratory. The analysis is given on the 5th-7th day of the cycle or within the time frame indicated by the doctor. In men, it can be determined at any time.

Three days before the test, do not physically overexert. One hour before the appearance in the laboratory, do not smoke. Blood surrenders on an empty stomach from a vein, before the analysis it is necessary to calm down and have a rest. More detailed instructions should be obtained from the doctor and the laboratory. A study is being carried out during the day.

If the hormone FSH is elevated, then you can suspect the following:

  • Seminoma;
  • Kidney failure;
  • Exposure to X-rays;
  • Dysfunctional bleeding from the uterus (with follicle persistence) ;
  • Testicular feminization;
  • Shershevsky-Turner syndrome, Swaer, ovarian malnutrition;
  • Primary hypogonadism in men;
  • Adenoma of the pituitary gland (basophilic);
  • Ovarian cysts (endometriosis).

Decrease in its level occurs in the following cases:

  • Contact with lead;
  • obesity;
  • Surgical interventions;
  • starvation;
  • Hyperprolactinemia;
  • Syndrome Shihana, polycystic ovaries;
  • Pituitary fascism;
  • Simmonds disease;
  • Hypogonadotropic hypogonadism;
  • Secondary amenorrhea.

It is recommended to pass the analysis in the following cases:

  • Endometriosis;
  • Growth retardation;
  • Miscarriage of pregnancy;
  • Check the effectiveness of hormone therapy;
  • Polycystic ovary syndrome;
  • Dysfunctional bleeding from the uterus;
  • Decreased potency and libido;
  • Amenorrhea and oligomenorrhea;
  • infertility;
  • Anovulation.

If the hormone FSH is elevated, treatment can not be immediately prescribed, because more research is needed. Most likely, the doctor will conduct a detailed questioning of the patient and advise additional tests.

For example, the relationship with luteinizing hormone (LH) is important . In 2 years after the onset of menstruation, it should be 1.5-2 times greater than FSH. It will be useful to pass other hormones that affect fertility:

  • progesterone;
  • Estradiol;
  • testosterone;
  • Prolactin;
  • DEA-sulfate.

Norms of FSH in MME / ml are as follows:

Children 0,3-6,9;

Males 1-11.9;

Before ovulation 1.8-11.4;

During it 4,9-20,5;

After ovulation 1,2-9,6;

Postmenopause 32-130.

Thus, FSH has a significant effect on the sexual function of both men and women. Its increased and decreased number may indicate serious pathologies.

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